PH-responsive...

1: Wang J, Xu W, Guo H, Ding J, Chen J, Guan J, Wang C. Selective intracellular

drug delivery from pH-responsive polyion complex micelle for enhanced malignancy

suppression in vivo. Colloids Surf B Biointerfaces. 2015 Jul 26;135:283-290. doi:

10.1016/j.colsurfb.2015.07.065. [Epub ahead of print] PubMed PMID: 26277711.

2: Colombo S, Brisander M, Haglöf J, Sjövall P, Andersson P, Østergaard J,

Malmsten M. Matrix effects in nilotinib formulations with pH-responsive polymer

produced by carbon dioxide-mediated precipitation. Int J Pharm. 2015 Aug 11. pii:

S0378-5173(15)30129-0. doi: 10.1016/j.ijpharm.2015.08.031. [Epub ahead of print]

PubMed PMID: 26276256.

3: Hebeish A, Farag S, Sharaf S, Shaheen TI. Radically new cellulose

nanocomposite hydrogels: Temperature and pH responsive characters. Int J Biol

Macromol. 2015 Aug 11. pii: S0141-8130(15)00549-8. doi:

10.1016/j.ijbiomac.2015.08.014. [Epub ahead of print] PubMed PMID: 26275463.

4: Meng LB, Zhang W, Li D, Li Y, Hu XY, Wang L, Li G. pH-Responsive

supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY

photosensitizer for chemo-photodynamic dual therapy. Chem Commun (Camb). 2015 Aug

13. [Epub ahead of print] PubMed PMID: 26270623.

5: Shrestha N, Shahbazi MA, Araújo F, Mäkilä E, Raula J, Kauppinen EI, Salonen J,

Sarmento B, Hirvonen J, Santos HA. Multistage pH-responsive mucoadhesive

nanocarriers prepared by aerosol flow reactor technology: A controlled dual

protein-drug delivery system. Biomaterials. 2015 Jul 26;68:9-20. doi:

10.1016/j.biomaterials.2015.07.045. [Epub ahead of print] PubMed PMID: 26253804.

6: Zhao H, Li Z, Yang B, Wang J, Li Y. Synthesis of Dual-functional Targeting

Probes for Cancer Theranostics Based on Iron Oxide Nanoparticles Coated by

Centipede-like Polymer Connected with pH-Responsive Anticancer Drug. J Biomater

Sci Polym Ed. 2015 Aug 7:1-30. [Epub ahead of print] PubMed PMID: 26249213.

7: Qi C, Zhu YJ, Sun TW, Wu J, Chen F. Microwave-assisted hydrothermal rapid

synthesis of amorphous calcium phosphate mesoporous microspheres using adenosine

5'-diphosphate and application in pH-responsive drug delivery. Chem Asian J. 2015

Aug 7. doi: 10.1002/asia.201500667. [Epub ahead of print] PubMed PMID: 26248600.

8: Eyley S, Vandamme D, Lama S, Van den Mooter G, Muylaert K, Thielemans W. CO(2)

controlled flocculation of microalgae using pH responsive cellulose nanocrystals.

Nanoscale. 2015 Aug 7. [Epub ahead of print] PubMed PMID: 26248574.

9: Yu M, Guo F, Wang J, Tan F, Li N. Photosensitizer-Loaded pH-Responsive Hollow

Gold Nanospheres for Single Light-Induced Photothermal/Photodynamic Therapy. ACS

Appl Mater Interfaces. 2015 Aug 19;7(32):17592-7. doi: 10.1021/acsami.5b05763.

Epub 2015 Aug 10. PubMed PMID: 26248033.

10: Ding Z, Li S, Cao X. Microbial Transglutaminase Separation by pH-Responsive

Affinity Precipitation with Crocein Orange G as the Ligand. Appl Biochem

Biotechnol. 2015 Aug 6. [Epub ahead of print] PubMed PMID: 26245259.

11: Pramod PS, Deshpande NU, Jayakannan M. Real-Time Drug Release Analysis of

Enzyme and pH Responsive Polysaccharide Nanovesicles. J Phys Chem B. 2015 Aug 12.

[Epub ahead of print] PubMed PMID: 26237375.

12: Peng T, Lee H, Lim S. Design of a reversible inversed pH-responsive caged

protein. Biomater Sci. 2015 Apr 17;3(4):627-35. doi: 10.1039/c4bm00313f. Epub

2015 Feb 9. PubMed PMID: 26222423.

13: Narambuena CF, Longo GS, Szleifer I. Lysozyme adsorption in pH-responsive

hydrogel thin-films: the non-trivial role of acid-base equilibrium. Soft Matter.

2015 Aug 12;11(33):6669-79. doi: 10.1039/c5sm00980d. PubMed PMID: 26219383.

14: Shi Q, Zhang L, Liu M, Zhang X, Zhang X, Xu X, Chen S, Li X, Zhang J.

Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived

nanomedicine in drug resistant cancer cells. Biomaterials. 2015 Jul

14;67:169-182. doi: 10.1016/j.biomaterials.2015.07.023. [Epub ahead of print]

PubMed PMID: 26218743.

15: Zhang S, Bellinger AM, Glettig DL, Barman R, Lee YL, Zhu J, Cleveland C,

Montgomery VA, Gu L, Nash LD, Maitland DJ, Langer R, Traverso G. A pH-responsive

supramolecular polymer gel as an enteric elastomer for use in gastric devices.

Nat Mater. 2015 Jul 27. doi: 10.1038/nmat4355. [Epub ahead of print] PubMed PMID:

26213897.

16: Arnould A, Gaillard C, Fameau AL. pH-responsive fatty acid self-assembly

transition induced by UV light. J Colloid Interface Sci. 2015 Nov 15;458:147-54.

doi: 10.1016/j.jcis.2015.07.043. Epub 2015 Jul 21. PubMed PMID: 26210918.

17: Guha A, Biswas N, Bhattacharjee K, Das P, Kuotsu K. In vitro evaluation of pH

responsive doxazosin loaded mesoporous silica nanoparticles: A smart approach in

drug delivery. Curr Drug Deliv. 2015 Jul 22. [Epub ahead of print] PubMed PMID:

26201344.

18: de León AS, Muñoz-Bonilla A, Gallardo A, Fernandez-Mayoralas A, Bernard J,

Rodríguez-Hernández J. Straightforward functionalization of breath figures:

Simultaneous orthogonal host-guest and pH-responsive interfaces. J Colloid

Interface Sci. 2015 Nov 1;457:272-80. doi: 10.1016/j.jcis.2015.06.039. Epub 2015

Jun 29. PubMed PMID: 26196710.

19: Hwang AA, Lee BY, Clemens DL, Dillon BJ, Zink JI, Horwitz MA. pH-Responsive

Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice.

Small. 2015 Jul 20. doi: 10.1002/smll.201500937. [Epub ahead of print] PubMed

PMID: 26193431.

20: Yao X, Chen L, Chen X, Xie Z, Ding J, He C, Zhang J, Chen X. pH-responsive

metallo-supramolecular nanogel for synergistic chemo-photodynamic therapy. Acta

Biomater. 2015 Jul 16. pii: S1742-7061(15)30022-2. doi:

10.1016/j.actbio.2015.07.024. [Epub ahead of print] PubMed PMID: 26190797.

21: Monzel C, Veschgini M, Madsen J, Lewis AL, Armes SP, Tanaka M. Fine

Adjustment of Interfacial Potential between pH-Responsive Hydrogels and

Cell-Sized Particles. Langmuir. 2015 Aug 11;31(31):8689-96. doi:

10.1021/acs.langmuir.5b01896. Epub 2015 Jul 31. PubMed PMID: 26190346.

22: Davaran S, Lotfipour F, Sedghipour N, Sedghipour MR, Alimohammadi S, Salehi

R. Preparation and in vivo evaluation of in situ gel system as dual

thermo-/pH-responsive nanocarriers for sustained ocular drug delivery. J

Microencapsul. 2015;32(5):511-9. doi: 10.3109/02652048.2015.1065915. Epub 2015

Jul 20. PubMed PMID: 26190215.

23: Solanki A, Thakore S. Cellulose crosslinked pH-responsive polyurethanes for

drug delivery: α-hydroxy acids as drug release modifiers. Int J Biol Macromol.

2015 Jul 16;80:683-691. doi: 10.1016/j.ijbiomac.2015.07.003. [Epub ahead of

print] PubMed PMID: 26188306.

24: Li J, Jia Y, Dong W, Wang A, Li J. pH responsive ATP carriers to drive

kinesin movement. Chem Commun (Camb). 2015 Jul 30;51(65):13044-6. doi:

10.1039/c5cc05251c. PubMed PMID: 26186258.

25: Li Z, Li J, Huang J, Zhang J, Cheng D, Shuai X. Synthesis and

Characterization of pH-Responsive Copolypeptides Vesicles for siRNA and

Chemotherapeutic Drug Co-Delivery. Macromol Biosci. 2015 Jul 17. doi:

10.1002/mabi.201500161. [Epub ahead of print] PubMed PMID: 26184375.

26: Yan L, Crayton SH, Thawani JP, Amirshaghaghi A, Tsourkas A, Cheng Z. A

pH-Responsive Drug-Delivery Platform Based on Glycol Chitosan-Coated Liposomes.

Small. 2015 Jul 16. doi: 10.1002/smll.201501412. [Epub ahead of print] PubMed

PMID: 26183232.

27: Bhuiyan MP, Aryal MP, Janic B, Karki K, Varma NR, Ewing JR, Arbab AS, Ali MM.

Concentration-independent MRI of pH with a dendrimer-based pH-responsive

nanoprobe. Contrast Media Mol Imaging. 2015 Jul 14. doi: 10.1002/cmmi.1651. [Epub

ahead of print] PubMed PMID: 26173742.

28: Bhaskar U, Hickey AM, Li G, Mundra RV, Zhang F, Fu L, Cai C, Ou Z, Dordick

JS, Linhardt RJ. A purification process for heparin and precursor polysaccharides

using the pH responsive behavior of chitosan. Biotechnol Prog. 2015 Jul 3. doi:

10.1002/btpr.2144. [Epub ahead of print] PubMed PMID: 26147064.

29: Chung MF, Liu HY, Lin KJ, Chia WT, Sung HW. A pH-Responsive Carrier System

that Generates NO Bubbles to Trigger Drug Release and Reverse

P-Glycoprotein-Mediated Multidrug Resistance. Angew Chem Int Ed Engl. 2015 Aug

17;54(34):9890-3. doi: 10.1002/anie.201504444. Epub 2015 Jul 1. PubMed PMID:

26136242.

30: Chen R, Jiang H, Gu H, Zhou Q, Wu J, Chen D, Zhang J. A pH-responsive

fluorescent [5]pseudorotaxane formed by self-assembly of cationic water-soluble

pillar[5]arenes and a tetraphenylethene derivative. Chem Commun (Camb). 2015 Jul

16;51(61):12220-3. doi: 10.1039/c5cc04720j. PubMed PMID: 26134923.

31: Wang C, Cheng H, Huang Y, Xu Z, Lin H, Zhang C. Facile sonochemical synthesis

of pH-responsive copper nanoclusters for selective and sensitive detection of

Pb(2+) in living cells. Analyst. 2015 Jul 27;140(16):5634-9. doi:

10.1039/c5an00741k. PubMed PMID: 26133700.

32: Qian J, Sullivan BP, Berkland C. pH-Responsive Micelle Sequestrant Polymers

Inhibit Fat Absorption. Biomacromolecules. 2015 Aug 10;16(8):2340-6. doi:

10.1021/acs.biomac.5b00560. Epub 2015 Jul 17. PubMed PMID: 26133544.

33: Kondo S, Asano Y, Koizumi N, Tatematsu K, Sawama Y, Sasai Y, Yamauchi Y,

Kuzuya M, Kurosawa S. Novel pH-Responsive Polymeric Micelles Prepared through

Self-assembly of Amphiphilic Block Copolymer with Poly-4-vinylpyridine Block

Synthesized by Mechanochemical Solid-State Polymerization. Chem Pharm Bull

(Tokyo). 2015;63(7):489-94. doi: 10.1248/cpb.c14-00869. PubMed PMID: 26133065.

34: Zhou Z, Gu F, Peng L, Hu Y, Wang Q. Spectroscopic analysis and in vitro

imaging applications of a pH responsive AIE sensor with a two-input inhibit

function. Chem Commun (Camb). 2015 Jul 14;51(60):12060-3. doi:

10.1039/c5cc03788c. PubMed PMID: 26121058.

35: Rossi B, Venuti V, D'Amico F, Gessini A, Mele A, Punta C, Melone L, Crupi V,

Majolino D, Trotta F, Masciovecchio C. Toward an understanding of the

thermosensitive behaviour of pH-responsive hydrogels based on cyclodextrins. Soft

Matter. 2015 Jul 15;11(29):5862-71. doi: 10.1039/c5sm01093d. PubMed PMID:

26107102.

36: Heinzelman P, Krais J, Ruben E, Pantazes R. Engineering pH responsive

fibronectin domains for biomedical applications. J Biol Eng. 2015 May 15;9:6.

doi: 10.1186/s13036-015-0004-1. eCollection 2015. PubMed PMID: 26106447; PubMed

Central PMCID: PMC4477602.

37: Lane DD, Su FY, Chiu DY, Srinivasan S, Wilson JT, Ratner DM, Stayton PS,

Convertine AJ. Dynamic intracellular delivery of antibiotics via pH-responsive

polymersomes. Polym Chem. 2015 Feb 28;6(8):1255-1266. PubMed PMID: 26097513;

PubMed Central PMCID: PMC4470576.

38: Luo YL, Han M, Xu F, Chen YS, Zhang YQ. pH-Responsive H-Type PMAA(2)

-b-HTPBN-b-PMAA(2) Four-Arm Star Block Copolymer Micelles for PTX Drug Release.

Macromol Biosci. 2015 Jun 11. doi: 10.1002/mabi.201500103. [Epub ahead of print]

PubMed PMID: 26096959.

39: Li L, Knickelbein K, Zhang L, Wang J, Obrinske M, Ma GZ, Zhang LM, Bitterman

L, Du W. Amphiphilic sugar poly(orthoesters) as pH-responsive nanoscopic

assemblies for acidity-enhanced drug delivery and cell killing. Chem Commun

(Camb). 2015 Aug 4;51(66):13078-81. doi: 10.1039/c5cc04078g. PubMed PMID:

26096366.

40: Wang X, Wu Y, Soesbe TC, Yu J, Zhao P, Kiefer GE, Sherry AD. A pH-Responsive

MRI Agent that Can Be Activated Beyond the Tissue Magnetization Transfer Window.

Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8662-4. doi: 10.1002/anie.201502497.

Epub 2015 Jun 11. PubMed PMID: 26096197.

41: Hu J, Xie L, Zhao W, Sun M, Liu X, Gao W. Design of tumor-homing and

pH-responsive polypeptide-doxorubicin nanoparticles with enhanced anticancer

efficacy and reduced side effects. Chem Commun (Camb). 2015 Jul 2;51(57):11405-8.

doi: 10.1039/c5cc04035c. PubMed PMID: 26086450.

42: Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA,

Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND,

Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H,

Bignell EM. Correction: The pH-Responsive PacC Transcription Factor of

Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during

Pulmonary Aspergillosis. PLoS Pathog. 2015 Jun 18;11(6):e1004943. doi:

10.1371/journal.ppat.1004943. eCollection 2015 Jun. PubMed PMID: 26086393; PubMed

Central PMCID: PMC4472839.

43: Tang X, Dai J, Xie J, Zhu Y, Zhu M, Wang Z, Xie C, Yao A, Liu T, Wang X, Chen

L, Jiang Q, Wang S, Liang Y, Xu C. Enhanced Antifungal Activity by Ab-Modified

Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer.

Nanoscale Res Lett. 2015 Dec;10(1):969. doi: 10.1186/s11671-015-0969-1. Epub 2015

Jun 10. PubMed PMID: 26061446; PubMed Central PMCID: PMC4486495.

44: Das S, Subuddhi U. pH-Responsive guar gum hydrogels for controlled delivery

of dexamethasone to the intestine. Int J Biol Macromol. 2015 Aug;79:856-63. doi:

10.1016/j.ijbiomac.2015.06.008. Epub 2015 Jun 7. PubMed PMID: 26056988.

45: Yamamura M, Takizawa H, Nabeshima T. Zwitterionic N2O2-Type Protonated

Dipyrrin Bearing a Phosphate Anionic Moiety as a pH-Responsive Fluorescence

Indicator. Org Lett. 2015 Jun 19;17(12):3114-7. doi: 10.1021/acs.orglett.5b01414.

Epub 2015 Jun 4. PubMed PMID: 26042936.

46: Gao Y, Zhou Y, Zhao L, Zhang C, Li Y, Li J, Li X, Liu Y. Enhanced antitumor

efficacy by cyclic RGDyK-conjugated and paclitaxel-loaded pH-responsive polymeric

micelles. Acta Biomater. 2015 Sep 1;23:127-35. doi: 10.1016/j.actbio.2015.05.021.

Epub 2015 May 23. PubMed PMID: 26013038.

47: Li Y, Chen H, Liu D, Wang W, Liu Y, Zhou S. pH-Responsive Shape Memory

Poly(ethylene glycol)-Poly(ε-caprolactone)-based Polyurethane/Cellulose

Nanocrystals Nanocomposite. ACS Appl Mater Interfaces. 2015 Jun

17;7(23):12988-99. doi: 10.1021/acsami.5b02940. Epub 2015 Jun 2. PubMed PMID:

26011859.

48: Mahdavinia GR, Etemadi H, Soleymani F. Magnetic/pH-responsive beads based on

caboxymethyl chitosan and κ-carrageenan and controlled drug release. Carbohydr

Polym. 2015 Sep 5;128:112-21. doi: 10.1016/j.carbpol.2015.04.022. Epub 2015 Apr

21. PubMed PMID: 26005146.

49: Gallon E, Matini T, Sasso L, Mantovani G, Armiñan de Benito A, Sanchis J,

Caliceti P, Alexander C, Vicent MJ, Salmaso S. Triblock Copolymer Nanovesicles

for pH-Responsive Targeted Delivery and Controlled Release of siRNA to Cancer

Cells. Biomacromolecules. 2015 Jul 13;16(7):1924-37. doi:

10.1021/acs.biomac.5b00286. Epub 2015 Jun 2. PubMed PMID: 25988940.

50: Chen Y, Ai K, Liu J, Sun G, Yin Q, Lu L. Multifunctional envelope-type

mesoporous silica nanoparticles for pH-responsive drug delivery and magnetic

resonance imaging. Biomaterials. 2015 Aug;60:111-20. doi:

10.1016/j.biomaterials.2015.05.003. Epub 2015 May 15. PubMed PMID: 25988726.

51: Zhang QM, Berg D, Mugo SM, Serpe MJ. Lipase-modified pH-responsive

microgel-based optical device for triglyceride sensing. Chem Commun (Camb). 2015

Jun 14;51(47):9726-8. doi: 10.1039/c5cc02853a. PubMed PMID: 25983030.

52: Buchner S, Schlundt A, Lassak J, Sattler M, Jung K. Structural and Functional

Analysis of the Signal-Transducing Linker in the pH-Responsive One-Component

System CadC of Escherichia coli. J Mol Biol. 2015 Jul 31;427(15):2548-61. doi:

10.1016/j.jmb.2015.05.001. Epub 2015 May 12. PubMed PMID: 25979249.

53: Kim BJ, Cheong H, Hwang BH, Cha HJ. Mussel-Inspired Protein Nanoparticles

Containing Iron(III)-DOPA Complexes for pH-Responsive Drug Delivery. Angew Chem

Int Ed Engl. 2015 Jun 15;54(25):7318-22. doi: 10.1002/anie.201501748. Epub 2015

May 12. PubMed PMID: 25968933.

54: Kim JY, Yang JH, Lee JH, Choi G, Park DH, Jo MR, Choi SJ, Choy JH. 2D

Inorganic-Antimalarial Drug-Polymer Hybrid with pH-Responsive Solubility. Chem

Asian J. 2015 May 12. doi: 10.1002/asia.201500347. [Epub ahead of print] PubMed

PMID: 25965188.

55: Ujjwal RR, Purohit MP, Patnaik S, Ojha U. General Reagent Free Route to pH

Responsive Polyacryloyl Hydrazide Capped Metal Nanogels for Synergistic

Anticancer Therapeutics. ACS Appl Mater Interfaces. 2015 Jun 3;7(21):11497-507.

doi: 10.1021/acsami.5b02452. Epub 2015 May 20. PubMed PMID: 25961335.

56: Kim HW, Kim JW, Jo SH, Lee CL, Lee WK, Park SS, Chung B, Yoo SI.

pH-Responsive assembly of metal nanoparticles and fluorescent dyes by diblock

copolymer micelles. Soft Matter. 2015 Jun 14;11(22):4402-7. doi:

10.1039/c5sm00824g. PubMed PMID: 25959746.

57: You JO, Rafat M, Almeda D, Maldonado N, Guo P, Nabzdyk CS, Chun M, LoGerfo

FW, Hutchinson JW, Pradhan-Nabzdyk LK, Auguste DT. pH-responsive scaffolds

generate a pro-healing response. Biomaterials. 2015 Jul;57:22-32. doi:

10.1016/j.biomaterials.2015.04.011. Epub 2015 Apr 21. PubMed PMID: 25956194.

58: Hsieh CJ, Chen YC, Hsieh PY, Liu SR, Wu SP, Hsieh YZ, Hsu HY. Graphene Oxide

Based Nanocarrier Combined with a pH-Sensitive Tracer: A Vehicle for Concurrent

pH Sensing and pH-Responsive Oligonucleotide Delivery. ACS Appl Mater Interfaces.

2015 Jun 3;7(21):11467-75. doi: 10.1021/acsami.5b02397. Epub 2015 May 18. PubMed

PMID: 25945595.

59: Manchun S, Dass CR, Cheewatanakornkool K, Sriamornsak P. Enhanced anti-tumor

effect of pH-responsive dextrin nanogels delivering doxorubicin on colorectal

cancer. Carbohydr Polym. 2015 Aug 1;126:222-30. doi:

10.1016/j.carbpol.2015.03.018. Epub 2015 Mar 18. PubMed PMID: 25933543.

60: Wang X, Li Z, Yang Y, Gong X, Liao Y, Xie X. Photomechanically Controlled

Encapsulation and Release from pH-Responsive and Photoresponsive Microcapsules.

Langmuir. 2015 May 19;31(19):5456-63. doi: 10.1021/acs.langmuir.5b01180. Epub

2015 May 7. PubMed PMID: 25924083.

61: Liu Q, Chen X, Jia J, Zhang W, Yang T, Wang L, Ma G. pH-Responsive

Poly(D,L-lactic-co-glycolic acid) Nanoparticles with Rapid Antigen Release

Behavior Promote Immune Response. ACS Nano. 2015 May 26;9(5):4925-38. doi:

10.1021/nn5066793. Epub 2015 Apr 24. PubMed PMID: 25898266.

62: Salehi R, Rasouli S, Hamishehkar H. Smart thermo/pH responsive magnetic

nanogels for the simultaneous delivery of doxorubicin and methotrexate. Int J

Pharm. 2015 Jun 20;487(1-2):274-84. doi: 10.1016/j.ijpharm.2015.04.051. Epub 2015

Apr 17. PubMed PMID: 25895723.

63: Bellingeri RV, Picco NY, Alustiza FE, Canova JV, Molina MA, Acevedo DF,

Barbero C, Vivas AB. pH-responsive hydrogels to protect IgY from gastric

conditions: in vitro evaluation. J Food Sci Technol. 2015 May;52(5):3117-22. doi:

10.1007/s13197-014-1337-3. Epub 2014 Apr 10. PubMed PMID: 25892818; PubMed

Central PMCID: PMC4397343.

64: Wang X, Niu D, Wu Q, Bao S, Su T, Liu X, Zhang S, Wang Q. Iron

oxide/manganese oxide co-loaded hybrid nanogels as pH-responsive magnetic

resonance contrast agents. Biomaterials. 2015 Jun;53:349-57. doi:

10.1016/j.biomaterials.2015.02.101. Epub 2015 Mar 17. PubMed PMID: 25890733.

65: Xu H, Zhang H, Wang D, Wu L, Liu X, Jiao Z. A facile route for rapid

synthesis of hollow mesoporous silica nanoparticles as pH-responsive delivery

carrier. J Colloid Interface Sci. 2015 Aug 1;451:101-7. doi:

10.1016/j.jcis.2015.03.057. Epub 2015 Apr 11. PubMed PMID: 25890118.

66: Heinzelman P, Schoborg JA, Jewett MC. pH responsive granulocyte

colony-stimulating factor variants with implications for treating Alzheimer's

disease and other central nervous system disorders. Protein Eng Des Sel. 2015 Apr

15. pii: gzv022. [Epub ahead of print] PubMed PMID: 25877663.

67: Niedermayer S, Weiss V, Herrmann A, Schmidt A, Datz S, Müller K, Wagner E,

Bein T, Bräuchle C. Multifunctional polymer-capped mesoporous silica

nanoparticles for pH-responsive targeted drug delivery. Nanoscale. 2015 May

7;7(17):7953-64. doi: 10.1039/c4nr07245f. PubMed PMID: 25865957.

68: Zhang Z, Lv Q, Gao X, Chen L, Cao Y, Yu S, He C, Chen X. pH-Responsive

Poly(ethylene glycol)/Poly(L-lactide) Supramolecular Micelles Based on Host-Guest

Interaction. ACS Appl Mater Interfaces. 2015 Apr 29;7(16):8404-11. doi:

10.1021/acsami.5b01213. Epub 2015 Apr 17. PubMed PMID: 25856564.

69: PLOS Pathogens Staff. Correction: The pH-responsive PacC transcription factor

of Aspergillus fumigatus governs epithelial entry and tissue invasion during

pulmonary aspergillosis. PLoS Pathog. 2015 Apr 8;11(4):e1004802. doi:

10.1371/journal.ppat.1004802. eCollection 2015 Apr. PubMed PMID: 25853727; PubMed

Central PMCID: PMC4390368.

70: Wang H, Zhao S, Agarwal P, Dumbleton J, Yu J, Lu X, He X. Multi-layered

polymeric nanoparticles for pH-responsive and sequenced release of theranostic

agents. Chem Commun (Camb). 2015 May 4;51(36):7733-6. doi: 10.1039/c5cc01833a.

PubMed PMID: 25850616.

71: Haldar U, Bauri K, Li R, Faust R, De P. Polyisobutylene-Based pH-Responsive

Self-Healing Polymeric Gels. ACS Appl Mater Interfaces. 2015 Apr

29;7(16):8779-88. doi: 10.1021/acsami.5b01272. Epub 2015 Apr 14. PubMed PMID:

25844579.

72: Li L, Gu J, Zhang J, Xie Z, Lu Y, Shen L, Dong Q, Wang Y. Injectable and

Biodegradable pH-Responsive Hydrogels for Localized and Sustained Treatment of

Human Fibrosarcoma. ACS Appl Mater Interfaces. 2015 Apr 22;7(15):8033-40. doi:

10.1021/acsami.5b00389. Epub 2015 Apr 10. PubMed PMID: 25838258.

73: Adachi N, Kaneko Y, Sekiguchi K, Sugiyama H, Sugeno M. pH-responsive

fluorescence chemical sensor constituted by conjugated polymers containing

pyridine rings. Luminescence. 2015 Mar 31. doi: 10.1002/bio.2898. [Epub ahead of

print] PubMed PMID: 25828634.

74: Bai L, Zhao Q, Wang J, Gao Y, Sha Z, Di D, Han N, Wang Y, Zhang J, Wang S.

Mechanism study on pH-responsive cyclodextrin capped mesoporous silica: effect of

different stalk densities and the type of cyclodextrin. Nanotechnology. 2015 Apr

24;26(16):165704. doi: 10.1088/0957-4484/26/16/165704. Epub 2015 Apr 1. PubMed

PMID: 25827241.

75: Fernando IR, Ferris DP, Frasconi M, Malin D, Strekalova E, Yilmaz MD,

Ambrogio MW, Algaradah MM, Hong MP, Chen X, Nassar MS, Botros YY, Cryns VL,

Stoddart JF. Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous

silica nanoparticles for drug delivery. Nanoscale. 2015 Apr 28;7(16):7178-83.

doi: 10.1039/c4nr07443b. PubMed PMID: 25820516.

76: Fu J, Shao Y, Wang L, Zhu Y. Lysosome-controlled efficient ROS overproduction

against cancer cells with a high pH-responsive catalytic nanosystem. Nanoscale.

2015 Apr 28;7(16):7275-83. doi: 10.1039/c5nr00706b. PubMed PMID: 25813671.

77: Chen L, Cao W, Grishkewich N, Berry RM, Tam KC. Synthesis and

characterization of pH-responsive and fluorescent poly (amidoamine)

dendrimer-grafted cellulose nanocrystals. J Colloid Interface Sci. 2015 Jul

15;450:101-8. doi: 10.1016/j.jcis.2015.03.002. Epub 2015 Mar 10. PubMed PMID:

25801138.

78: Zhang W, Xing L, Wang H, Liu X, Feng Y, Gao C. Preparation of novel porphyrin

nanomaterials based on the pH-responsive shape evolution of porphyrin

microspheres. Langmuir. 2015 Apr 14;31(14):4330-40. doi:

10.1021/acs.langmuir.5b00322. Epub 2015 Apr 2. PubMed PMID: 25798879.

79: Wu X, Li Y, Lin C, Hu XY, Wang L. GSH- and pH-responsive drug delivery system

constructed by water-soluble pillar[5]arene and lysine derivative for

controllable drug release. Chem Commun (Camb). 2015 Apr 21;51(31):6832-5. doi:

10.1039/c5cc01393c. PubMed PMID: 25790033.

80: Zhang S, Qian X, Zhang L, Peng W, Chen Y. Composition-property relationships

in multifunctional hollow mesoporous carbon nanosystems for PH-responsive

magnetic resonance imaging and on-demand drug release. Nanoscale. 2015 May

7;7(17):7632-43. doi: 10.1039/c5nr00451a. PubMed PMID: 25785502.

81: Negrini R, Fong WK, Boyd BJ, Mezzenga R. pH-responsive lyotropic liquid

crystals and their potential therapeutic role in cancer treatment. Chem Commun

(Camb). 2015 Apr 18;51(30):6671-4. doi: 10.1039/c4cc10274f. PubMed PMID:

25783035.

82: Mac Kenna N, Calvert P, Morrin A. Impedimetric transduction of swelling in

pH-responsive hydrogels. Analyst. 2015 May 7;140(9):3003-11. doi:

10.1039/c4an02252a. Epub 2015 Mar 13. PubMed PMID: 25768307.

83: Ohta S, Yamura K, Inasawa S, Yamaguchi Y. Aggregates of silicon quantum dots

as a drug carrier: selective intracellular drug release based on pH-responsive

aggregation/dispersion. Chem Commun (Camb). 2015 Apr 14;51(29):6422-5. doi:

10.1039/c5cc00925a. PubMed PMID: 25765844.

84: Dai L, Zhang Q, Li J, Shen X, Mu C, Cai K. Dendrimerlike mesoporous silica

nanoparticles as pH-responsive nanocontainers for targeted drug delivery and

bioimaging. ACS Appl Mater Interfaces. 2015 Apr 8;7(13):7357-72. doi:

10.1021/acsami.5b00746. Epub 2015 Mar 24. PubMed PMID: 25765172.

85: Tang C, Amin D, Messersmith PB, Anthony JE, Prud'homme RK. Polymer directed

self-assembly of pH-responsive antioxidant nanoparticles. Langmuir. 2015 Mar

31;31(12):3612-20. doi: 10.1021/acs.langmuir.5b00213. Epub 2015 Mar 20. PubMed

PMID: 25760226.

86: Chen P, Qiu M, Deng C, Meng F, Zhang J, Cheng R, Zhong Z. pH-Responsive

chimaeric pepsomes based on asymmetric poly(ethylene

glycol)-b-poly(l-leucine)-b-poly(l-glutamic acid) triblock copolymer for

efficient loading and active intracellular delivery of doxorubicin hydrochloride.

Biomacromolecules. 2015 Apr 13;16(4):1322-30. doi: 10.1021/acs.biomac.5b00113.

Epub 2015 Mar 19. PubMed PMID: 25759951.

87: Xu Z, Liu S, Kang Y, Wang M. Glutathione- and pH-responsive nonporous silica

prodrug nanoparticles for controlled release and cancer therapy. Nanoscale. 2015

Mar 19;7(13):5859-68. doi: 10.1039/c5nr00297d. PubMed PMID: 25757484.

88: Hill MR, MacKrell EJ, Forsthoefel CP, Jensen SP, Chen M, Moore GA, He ZL,

Sumerlin BS. Biodegradable and pH-responsive nanoparticles designed for

site-specific delivery in agriculture. Biomacromolecules. 2015 Apr

13;16(4):1276-82. doi: 10.1021/acs.biomac.5b00069. Epub 2015 Mar 10. PubMed PMID:

25756603.

89: Zhang YJ, Zhan X, Wang L, Ho RJ, Sasaki T. pH-responsive artemisinin dimer in

lipid nanoparticles are effective against human breast cancer in a xenograft

model. J Pharm Sci. 2015 May;104(5):1815-24. doi: 10.1002/jps.24407. Epub 2015

Mar 9. PubMed PMID: 25753991.

90: Shao W, Liu H, Liu X, Sun H, Wang S, Zhang R. pH-responsive release behavior

and anti-bacterial activity of bacterial cellulose-silver nanocomposites. Int J

Biol Macromol. 2015 May;76:209-17. doi: 10.1016/j.ijbiomac.2015.02.048. Epub 2015

Mar 5. PubMed PMID: 25748842.

91: Nguyen BT, Wang W, Saunders BR, Benyahia L, Nicolai T. pH-responsive

water-in-water Pickering emulsions. Langmuir. 2015 Mar 31;31(12):3605-11. doi:

10.1021/la5049024. Epub 2015 Mar 17. PubMed PMID: 25743065.

92: Tan L, Yang MY, Wu HX, Tang ZW, Xiao JY, Liu CJ, Zhuo RX. Glucose- and

pH-responsive nanogated ensemble based on polymeric network capped mesoporous

silica. ACS Appl Mater Interfaces. 2015 Mar 25;7(11):6310-6. doi:

10.1021/acsami.5b00631. Epub 2015 Mar 10. PubMed PMID: 25735191.

93: Wang M, Sun J, Zhai Y, Lian H, Luo C, Li L, Du Y, Zhang D, Ding W, Qiu S, Liu

Y, Kou L, Han X, Xiang R, Wang Y, He Z. Enteric polymer based on pH-responsive

aliphatic polycarbonate functionalized with vitamin E to facilitate oral delivery

of tacrolimus. Biomacromolecules. 2015 Apr 13;16(4):1179-90. doi:

10.1021/bm501847u. Epub 2015 Mar 18. PubMed PMID: 25714622.

94: Butt AM, Mohd Amin MC, Katas H. Synergistic effect of pH-responsive

folate-functionalized poloxamer 407-TPGS-mixed micelles on targeted delivery of

anticancer drugs. Int J Nanomedicine. 2015 Feb 13;10:1321-34. doi:

10.2147/IJN.S78438. eCollection 2015. PubMed PMID: 25709451; PubMed Central

PMCID: PMC4335624.

95: Zhang Q, Tang J, Ran R, Liu Y, Zhang Z, Gao H, He Q. Development of an

anti-microbial peptide-mediated liposomal delivery system: a novel approach

towards pH-responsive anti-microbial peptides. Drug Deliv. 2015 Feb 19:1-8. [Epub

ahead of print] PubMed PMID: 25693639.

96: Zhao D, Li B, Han J, Yang Y, Zhang X, Wu G. PH responsive polypeptide based

polymeric micelles for anticancer drug delivery. J Biomed Mater Res A. 2015

Sep;103(9):3045-53. doi: 10.1002/jbm.a.35434. Epub 2015 Mar 14. PubMed PMID:

25689362.

97: Chen J, Zhang WJ, Guo Z, Wang HB, Wang DD, Zhou JJ, Chen QW. pH-responsive

iron manganese silicate nanoparticles as T1-T2* dual-modal imaging probes for

tumor diagnosis. ACS Appl Mater Interfaces. 2015 Mar 11;7(9):5373-83. doi:

10.1021/acsami.5b00727. Epub 2015 Feb 27. PubMed PMID: 25685956.

98: Milani AH, Bramhill J, Freemont AJ, Saunders BR. Swelling and mechanical

properties of hydrogels composed of binary blends of inter-linked pH-responsive

microgel particles. Soft Matter. 2015 Apr 7;11(13):2586-95. doi:

10.1039/c4sm02432j. PubMed PMID: 25683792.

99: Wang Y, Ma X, Ding C, Jia L. pH-responsive deoxyribonucleic acid

capture/release by polydopamine functionalized magnetic nanoparticles. Anal Chim

Acta. 2015 Mar 3;862:33-40. doi: 10.1016/j.aca.2015.01.009. Epub 2015 Jan 8.

PubMed PMID: 25682426.

100: Liu J, Deng H, Liu Q, Chu L, Zhang Y, Yang C, Zhao X, Huang P, Deng L, Dong

A, Liu J. Integrin-targeted pH-responsive micelles for enhanced efficiency of

anticancer treatment in vitro and in vivo. Nanoscale. 2015 Mar 14;7(10):4451-60.

doi: 10.1039/c4nr07435a. PubMed PMID: 25679795.

101: Gao Y, Zhang C, Zhou Y, Li J, Zhao L, Li Y, Liu Y, Li X. Endosomal

pH-Responsive Polymer-Based Dual-Ligand-Modified Micellar Nanoparticles for Tumor

Targeted Delivery and Facilitated Intracellular Release of Paclitaxel. Pharm Res.

2015 Aug;32(8):2649-62. doi: 10.1007/s11095-015-1650-1. Epub 2015 Feb 13. PubMed

PMID: 25676595.

102: Zhang Y, An P, Liu X. Bell-shaped sol-gel-sol conversions in pH-responsive

worm-based nanostructured fluid. Soft Matter. 2015 Mar 21;11(11):2080-4. doi:

10.1039/c4sm02845g. PubMed PMID: 25675411.

103: Goyal N, Mangunuru HP, Parikh B, Shrestha S, Wang G. Synthesis and

characterization of pH responsive D-glucosamine based molecular gelators.

Beilstein J Org Chem. 2014 Dec 23;10:3111-21. doi: 10.3762/bjoc.10.328.

eCollection 2014. PubMed PMID: 25670980; PubMed Central PMCID: PMC4311663.

104: Woraphatphadung T, Sajomsang W, Gonil P, Saesoo S, Opanasopit P. Synthesis

and characterization of pH-responsive N-naphthyl-N,O-succinyl chitosan micelles

for oral meloxicam delivery. Carbohydr Polym. 2015 May 5;121:99-106. doi:

10.1016/j.carbpol.2014.12.039. Epub 2015 Jan 2. PubMed PMID: 25659677.

105: Wang W, Milani AH, Carney L, Yan J, Cui Z, Thaiboonrod S, Saunders BR.

Doubly crosslinked microgel-colloidosomes: a versatile method for pH-responsive

capsule assembly using microgels as macro-crosslinkers. Chem Commun (Camb). 2015

Mar 4;51(18):3854-7. doi: 10.1039/c4cc10169c. PubMed PMID: 25655036.

106: Danilovtseva EN, Aseyev V, Belozerova OY, Zelinskiy SN, Annenkov VV.

Bioinspired thermo- and pH-responsive polymeric amines: multimolecular aggregates

in aqueous media and matrices for silica/polymer nanocomposites. J Colloid

Interface Sci. 2015 May 15;446:1-10. doi: 10.1016/j.jcis.2015.01.021. Epub 2015

Jan 20. PubMed PMID: 25646785.

107: Sun D, Ding J, Xiao C, Chen J, Zhuang X, Chen X. pH-Responsive Reversible

PEGylation Improves Performance of Antineoplastic Agent. Adv Healthc Mater. 2015

Apr 22;4(6):844-55. doi: 10.1002/adhm.201400736. Epub 2015 Feb 2. PubMed PMID:

25645303.

108: Li XS, Ke MR, Huang W, Ye CH, Huang JD. A pH-responsive layered double

hydroxide (LDH)-phthalocyanine nanohybrid for efficient photodynamic therapy.

Chemistry. 2015 Feb 16;21(8):3310-7. doi: 10.1002/chem.201404514. Epub 2015 Jan

9. PubMed PMID: 25639348.

109: Zhou J, Zhang W, Hong C, Pan C. Silica nanotubes decorated by pH-responsive

diblock copolymers for controlled drug release. ACS Appl Mater Interfaces. 2015

Feb 18;7(6):3618-25. doi: 10.1021/am507832n. Epub 2015 Feb 6. PubMed PMID:

25625307.

110: Sun J, Wei W, Zhao D, Hu Q, Liu X. Liquid marbles prepared from

pH-responsive self-assembled micelles. Soft Matter. 2015 Mar 14;11(10):1954-61.

doi: 10.1039/c4sm02832e. PubMed PMID: 25621854.

111: Zhang P, Kong J. Doxorubicin-tethered fluorescent silica nanoparticles for

pH-responsive anticancer drug delivery. Talanta. 2015 Mar;134:501-7. doi:

10.1016/j.talanta.2014.09.041. Epub 2014 Oct 29. PubMed PMID: 25618700.

112: Chen D, Sun J, Sun K, Liu W, Wu Z. In vivo evaluation of novel ketal-based

oligosaccharides of hyaluronan micelles as multifunctional CD44

receptor-targeting and tumor pH-responsive carriers. Artif Cells Nanomed

Biotechnol. 2015 Jan 23:1-5. [Epub ahead of print] PubMed PMID: 25613026.

113: Zhao Y, Zhou Y, Wang D, Gao Y, Li J, Ma S, Zhao L, Zhang C, Liu Y, Li X.

pH-responsive polymeric micelles based on

poly(2-ethyl-2-oxazoline)-poly(D,L-lactide) for tumor-targeting and controlled

delivery of doxorubicin and P-glycoprotein inhibitor. Acta Biomater. 2015

Apr;17:182-92. doi: 10.1016/j.actbio.2015.01.010. Epub 2015 Jan 19. PubMed PMID:

25612838.

114: Yan Y, Sun Y, Yu H, Xu H, Lu JR. Self-assembly and nanoaggregation of a pH

responsive DNA hybrid amphiphile. Soft Matter. 2015 Mar 7;11(9):1748-54. doi:

10.1039/c4sm02499k. PubMed PMID: 25603356.

115: Boas M, Gradys A, Vasilyev G, Burman M, Zussman E. Electrospinning

polyelectrolyte complexes: pH-responsive fibers. Soft Matter. 2015 Mar

7;11(9):1739-47. doi: 10.1039/c4sm02618g. PubMed PMID: 25601204.

116: Liang W, Chow MY, Lau PN, Zhou QT, Kwok PC, Leung GP, Mason AJ, Chan HK,

Poon LL, Lam JK. Inhalable dry powder formulations of siRNA and pH-responsive

peptides with antiviral activity against H1N1 influenza virus. Mol Pharm. 2015

Mar 2;12(3):910-21. doi: 10.1021/mp500745v. Epub 2015 Jan 30. PubMed PMID:

25599953.

117: Song F, Hu W, Xiao L, Cao Z, Li X, Zhang C, Liao L, Liu L. Enzymatically

cross-linked hyaluronic acid/graphene oxide nanocomposite hydrogel with

pH-responsive release. J Biomater Sci Polym Ed. 2015;26(6):339-52. doi:

10.1080/09205063.2015.1007413. Epub 2015 Feb 11. PubMed PMID: 25598448.

118: Zhan X, Tran KK, Wang L, Shen H. Controlled Endolysosomal Release of Agents

by pH-responsive Polymer Blend Particles. Pharm Res. 2015 Jul;32(7):2280-91. doi:

10.1007/s11095-015-1619-0. Epub 2015 Jan 16. PubMed PMID: 25592550; PubMed

Central PMCID: PMC4449789.

119: Adhikari C, Das A, Chakraborty A. Controlled release of a sparingly

water-soluble anticancer drug through pH-responsive functionalized

gold-nanoparticle-decorated liposomes. Chemphyschem. 2015 Mar 16;16(4):866-71.

doi: 10.1002/cphc.201402748. Epub 2015 Jan 13. PubMed PMID: 25586408.

120: Lee HS, Dastgheyb SS, Hickok NJ, Eckmann DM, Composto RJ. Targeted release

of tobramycin from a pH-responsive grafted bilayer challenged with S. aureus.

Biomacromolecules. 2015 Feb 9;16(2):650-9. doi: 10.1021/bm501751v. Epub 2015 Jan

27. PubMed PMID: 25585173; PubMed Central PMCID: PMC4323770.

121: Siebler C, Trapp N, Wennemers H. Crystal structure of (4S)-aminoproline:

conformational insight into a pH-responsive proline derivative. J Pept Sci. 2015

Mar;21(3):208-11. doi: 10.1002/psc.2734. Epub 2015 Jan 8. PubMed PMID: 25581874.

122: Fu L, Sun C, Yan L. Galactose targeted pH-responsive copolymer conjugated

with near infrared fluorescence probe for imaging of intelligent drug delivery.

ACS Appl Mater Interfaces. 2015 Jan 28;7(3):2104-15. doi: 10.1021/am508291k. Epub

2015 Jan 16. PubMed PMID: 25569169.

123: Ping Y, Guo J, Ejima H, Chen X, Richardson JJ, Sun H, Caruso F.

pH-Responsive Capsules Engineered from Metal-Phenolic Networks for Anticancer

Drug Delivery. Small. 2015 May 6;11(17):2032-6. doi: 10.1002/smll.201403343. Epub

2015 Jan 3. PubMed PMID: 25556334.

124: Ahn H, Hong J, Kim SY, Choi I, Park MJ. A pH-responsive molecular switch

with tricolor luminescence. ACS Appl Mater Interfaces. 2015 Jan 14;7(1):704-12.

doi: 10.1021/am5070188. Epub 2015 Jan 6. PubMed PMID: 25532587.

125: Smirnova E, Safenkova I, Stein-Margolina V, Shubin V, Polshakov V, Gurvits

B. pH-responsive modulation of insulin aggregation and structural transformation

of the aggregates. Biochimie. 2015 Feb;109:49-59. doi:

10.1016/j.biochi.2014.12.006. Epub 2014 Dec 16. PubMed PMID: 25527324.

126: Wilson JT, Postma A, Keller S, Convertine AJ, Moad G, Rizzardo E, Meagher L,

Chiefari J, Stayton PS. Enhancement of MHC-I antigen presentation via

architectural control of pH-responsive, endosomolytic polymer nanoparticles. AAPS

J. 2015 Mar;17(2):358-69. doi: 10.1208/s12248-014-9697-1. Epub 2014 Dec 12.

PubMed PMID: 25501498; PubMed Central PMCID: PMC4365097.

127: Patel V, Bharatiya B, Ray D, Aswal VK, Bahadur P. Investigations on

microstructural changes in pH responsive mixed micelles of Triton X-100 and bile

salt. J Colloid Interface Sci. 2015 Mar 1;441:106-12. doi:

10.1016/j.jcis.2014.11.027. Epub 2014 Nov 18. PubMed PMID: 25498486.

128: Yu P, Yu H, Guo C, Cui Z, Chen X, Yin Q, Zhang P, Yang X, Cui H, Li Y.

Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted

pH-responsive micelles. Acta Biomater. 2015 Mar;14:115-24. doi:

10.1016/j.actbio.2014.12.001. Epub 2014 Dec 9. PubMed PMID: 25498306.

129: Gui W, Wang W, Jiao X, Chen L, Wen Y, Zhang X. Dual-cargo selectively

controlled release based on a pH-responsive mesoporous silica system.

Chemphyschem. 2015 Feb 23;16(3):607-13. doi: 10.1002/cphc.201402732. Epub 2014

Dec 9. PubMed PMID: 25492672.

130: Amoli-Diva M, Pourghazi K, Mashhadizadeh MH. Magnetic pH-responsive

poly(methacrylic acid-co-acrylic acid)-co-polyvinylpyrrolidone magnetic

nano-carrier for controlled delivery of fluvastatin. Mater Sci Eng C Mater Biol

Appl. 2015 Feb;47:281-9. doi: 10.1016/j.msec.2014.11.050. Epub 2014 Nov 13.

PubMed PMID: 25492199.

131: Tan L, Liu J, Zhou W, Wei J, Peng Z. A novel thermal and pH responsive drug

delivery system based on ZnO@PNIPAM hybrid nanoparticles. Mater Sci Eng C Mater

Biol Appl. 2014 Dec;45:524-9. doi: 10.1016/j.msec.2014.09.031. Epub 2014 Sep 18.

PubMed PMID: 25491860.

132: Watkins KA, Chen R. pH-responsive, lysine-based hydrogels for the oral

delivery of a wide size range of molecules. Int J Pharm. 2015 Jan

30;478(2):496-503. doi: 10.1016/j.ijpharm.2014.12.005. Epub 2014 Dec 6. PubMed

PMID: 25490181.

133: Kim AJ, Woodworth GF, Boylan NJ, Suk JS, Hanes J. Highly compacted

pH-responsive DNA nanoparticles mediate transgene silencing in experimental

glioma. J Mater Chem B Mater Biol Med. 2014 Dec 14;2(46):8165-8173. PubMed PMID:

25485114; PubMed Central PMCID: PMC4254827.

134: Ast S, Rutledge PJ, Todd MH. The properties and performance of a

pH-responsive functionalised nanoparticle. Faraday Discuss. 2014;175:171-87. doi:

10.1039/c4fd00110a. PubMed PMID: 25483149.

135: Duan LN, Dang QQ, Han CY, Zhang XM. An interpenetrated bioactive nonlinear

optical MOF containing a coordinated quinolone-like drug and Zn(II) for

pH-responsive release. Dalton Trans. 2015 Jan 28;44(4):1800-4. doi:

10.1039/c4dt02672a. PubMed PMID: 25473930.

136: Ben Messaoud G, Sánchez-González L, Jacquot A, Probst L, Desobry S.

Alginate/sodium caseinate aqueous-core capsules: a pH-responsive matrix. J

Colloid Interface Sci. 2015 Feb 15;440:1-8. doi: 10.1016/j.jcis.2014.10.042. Epub

2014 Nov 1. PubMed PMID: 25460682.

137: Sajomsang W, Gonil P, Saesoo S, Ruktanonchai UR, Srinuanchai W,

Puttipipatkhachorn S. Synthesis and anticervical cancer activity of novel pH

responsive micelles for oral curcumin delivery. Int J Pharm. 2014 Dec

30;477(1-2):261-72. doi: 10.1016/j.ijpharm.2014.10.042. Epub 2014 Oct 18. PubMed

PMID: 25455774.

138: Zhang Q, Ran R, Zhang L, Liu Y, Mei L, Zhang Z, Gao H, He Q. Simultaneous

delivery of therapeutic antagomirs with paclitaxel for the management of

metastatic tumors by a pH-responsive anti-microbial peptide-mediated liposomal

delivery system. J Control Release. 2015 Jan 10;197:208-18. doi:

10.1016/j.jconrel.2014.11.010. Epub 2014 Nov 15. PubMed PMID: 25445692.

139: Hao M, Liu C, Peng L, Li J, Lu W, Jiang L. Shape separation of gold

nanoparticles using a pH-responsive amphiphilic dendrimer according to their

shape anisotropy distinction. J Colloid Interface Sci. 2015 Jan 1;437:311-5. doi:

10.1016/j.jcis.2014.09.052. Epub 2014 Sep 30. PubMed PMID: 25441366.

140: Longo GS, de la Cruz MO, Szleifer I. Equilibrium adsorption of hexahistidine

on pH-responsive hydrogel nanofilms. Langmuir. 2014 Dec 23;30(50):15335-44. doi:

10.1021/la5040382. Epub 2014 Dec 12. PubMed PMID: 25434993.

141: Sun J, Yi C, Wei W, Zhao D, Hu Q, Liu X. Nanohybrids from direct chemical

self-assembly of poly(styrene-alt-maleic anhydride) as pH-responsive particulate

emulsifiers. Langmuir. 2014 Dec 16;30(49):14757-64. doi: 10.1021/la504281b. Epub

2014 Dec 5. PubMed PMID: 25423487.

142: Zhao Y, Luo Z, Li M, Qu Q, Ma X, Yu SH, Zhao Y. A preloaded amorphous

calcium carbonate/doxorubicin@silica nanoreactor for pH-responsive delivery of an

anticancer drug. Angew Chem Int Ed Engl. 2015 Jan 12;54(3):919-22. doi:

10.1002/anie.201408510. Epub 2014 Nov 24. PubMed PMID: 25422068.

143: Lovett JR, Warren NJ, Ratcliffe LP, Kocik MK, Armes SP. pH-responsive

non-ionic diblock copolymers: ionization of carboxylic acid end-groups induces an

order-order morphological transition. Angew Chem Int Ed Engl. 2015 Jan

19;54(4):1279-83. doi: 10.1002/anie.201409799. Epub 2014 Nov 21. PubMed PMID:

25418214; PubMed Central PMCID: PMC4312895.

144: Frohm B, DeNizio JE, Lee DS, Gentile L, Olsson U, Malm J, Akerfeldt KS,

Linse S. A peptide from human semenogelin I self-assembles into a pH-responsive

hydrogel. Soft Matter. 2015 Jan 14;11(2):414-21. doi: 10.1039/c4sm01793e. PubMed

PMID: 25408475.

145: Wang S, Zhang L, Dong C, Su L, Wang H, Chang J. Smart pH-responsive

upconversion nanoparticles for enhanced tumor cellular internalization and

near-infrared light-triggered photodynamic therapy. Chem Commun (Camb).

2015;51(2):406-8. doi: 10.1039/c4cc08178a. Epub 2014 Nov 18. PubMed PMID:

25406644.

146: Joshi N, Shirsath N, Singh A, Joshi KS, Banerjee R. Endogenous lung

surfactant inspired pH responsive nanovesicle aerosols: pulmonary compatible and

site-specific drug delivery in lung metastases. Sci Rep. 2014 Nov 18;4:7085. doi:

10.1038/srep07085. PubMed PMID: 25403950; PubMed Central PMCID: PMC4235800.

147: Zhang X, Achazi K, Haag R. Boronate cross-linked ATP- and pH-responsive

nanogels for intracellular delivery of anticancer drugs. Adv Healthc Mater. 2015

Mar 11;4(4):585-92. doi: 10.1002/adhm.201400550. Epub 2014 Nov 12. PubMed PMID:

25388994.

148: Zhou C, Chen T, Wu C, Zhu G, Qiu L, Cui C, Hou W, Tan W. Aptamer CaCO3

nanostructures: a facile, pH-responsive, specific platform for targeted

anticancer theranostics. Chem Asian J. 2015 Jan;10(1):166-71. doi:

10.1002/asia.201403115. Epub 2014 Nov 6. PubMed PMID: 25377905; PubMed Central

PMCID: PMC4323099.

149: Zhou X, Luo S, Tang R, Wang R, Wang J. Diblock copolymers of polyethylene

glycol and a polymethacrylamide with side-chains containing twin ortho ester

rings: synthesis, characterization, and evaluation as potential pH-responsive

micelles. Macromol Biosci. 2015 Mar;15(3):385-94. doi: 10.1002/mabi.201400395.

Epub 2014 Nov 5. PubMed PMID: 25371162.

150: Hu XY, Jia K, Cao Y, Li Y, Qin S, Zhou F, Lin C, Zhang D, Wang L. Dual

photo- and pH-responsive supramolecular nanocarriers based on water-soluble

pillar[6]arene and different azobenzene derivatives for intracellular anticancer

drug delivery. Chemistry. 2015 Jan 12;21(3):1208-20. doi: 10.1002/chem.201405095.

Epub 2014 Nov 4. PubMed PMID: 25370941.

151: Mildner R, Menzel H. Hydrophobic spacers enhance the helicity and lectin

binding of synthetic, pH-responsive glycopolypeptides. Biomacromolecules. 2014

Dec 8;15(12):4528-33. doi: 10.1021/bm501325n. Epub 2014 Nov 21. PubMed PMID:

25365471.

152: Lee ES, Na K, Bae YH. 17. Histidine based pH-responsive polymeric micelle

for tumor: Original research article: Polymeric micelle for tumor pH

folate-mediated targeting, 2003. J Control Release. 2014 Sep 28;190:61-3. PubMed

PMID: 25356490.

153: Guo W, Yang C, Lin H, Qu F. P(EO-co-LLA) functionalized Fe3O4@mSiO2

nanocomposites for thermo/pH responsive drug controlled release and hyperthermia.

Dalton Trans. 2014 Dec 28;43(48):18056-65. doi: 10.1039/c4dt02441a. PubMed PMID:

25353400.

154: Richter M, Steinhilber D, Haag R, von Klitzing R. Visualization of real-time

degradation of pH-responsive polyglycerol nanogels via atomic force microscopy.

Macromol Rapid Commun. 2014 Dec;35(23):2018-22. doi: 10.1002/marc.201400449. Epub

2014 Oct 27. PubMed PMID: 25346236.

155: Ast S, Rutledge PJ, Todd MH. pH-Responsive quantum dots (RQDs) that combine

a fluorescent nanoparticle with a pH-sensitive dye. Phys Chem Chem Phys. 2014 Dec

14;16(46):25255-7. doi: 10.1039/c4cp03914a. Epub 2014 Oct 22. PubMed PMID:

25338264.

156: Lu H, Shi Q, Huang Z. pH-responsive anionic wormlike micelle based on sodium

oleate induced by NaCl. J Phys Chem B. 2014 Oct 30;118(43):12511-7. doi:

10.1021/jp506809m. Epub 2014 Oct 22. PubMed PMID: 25336331.

157: Choi W, Kang S, Mok Y, Park E, Song Y, Choi SJ, Lee Y. Unlocking the

pH-responsive degradability of fumaramic acid derivatives using

photoisomerization. Chemistry. 2014 Nov 24;20(48):15715-8. doi:

10.1002/chem.201405205. Epub 2014 Oct 21. PubMed PMID: 25336298.

158: Jang JH, Orbán M, Wang S, Huh do S. Adsorption-desorption oscillations of

nanoparticles on a honeycomb-patterned pH-responsive hydrogel surface in a closed

reaction system. Phys Chem Chem Phys. 2014 Dec 14;16(46):25296-305. doi:

10.1039/c4cp03083d. Epub 2014 Oct 22. PubMed PMID: 25336297.

159: Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA,

Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND,

Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H,

Bignell EM. The pH-responsive PacC transcription factor of Aspergillus fumigatus

governs epithelial entry and tissue invasion during pulmonary aspergillosis. PLoS

Pathog. 2014 Oct 16;10(10):e1004413. doi: 10.1371/journal.ppat.1004413.

eCollection 2014 Oct. PubMed PMID: 25329394; PubMed Central PMCID: PMC4199764.

160: Park D, Cho Y, Goh SH, Choi Y. Hyaluronic acid-polypyrrole nanoparticles as

pH-responsive theranostics. Chem Commun (Camb). 2014 Dec 11;50(95):15014-7. doi:

10.1039/c4cc06349j. PubMed PMID: 25327482.

161: Gitsov I, Wang L, Vladimirov N, Simonyan A, Kiemle DJ, Schutz A. "Green"

synthesis of unnatural poly(Amino Acid)s with Zwitterionic character and

pH-responsive solution behavior, mediated by linear-dendritic laccase complexes.

Biomacromolecules. 2014 Nov 10;15(11):4082-95. doi: 10.1021/bm501126a. Epub 2014

Oct 28. PubMed PMID: 25325886.

162: Hu J, Liu G, Wang C, Liu T, Zhang G, Liu S. Spatiotemporal monitoring

endocytic and cytosolic pH gradients with endosomal escaping pH-responsive

micellar nanocarriers. Biomacromolecules. 2014 Nov 10;15(11):4293-301. doi:

10.1021/bm501296d. Epub 2014 Oct 28. PubMed PMID: 25317967.

163: Cui Z, Milani AH, Greensmith PJ, Yan J, Adlam DJ, Hoyland JA, Kinloch IA,

Freemont AJ, Saunders BR. A study of physical and covalent hydrogels containing

pH-responsive microgel particles and graphene oxide. Langmuir. 2014 Nov

11;30(44):13384-93. doi: 10.1021/la5032015. Epub 2014 Oct 28. PubMed PMID:

25313805.

164: Wang Z, Rutjes FP, van Hest JC. pH responsive polymersome Pickering emulsion

for simple and efficient Janus polymersome fabrication. Chem Commun (Camb). 2014

Dec 4;50(93):14550-3. doi: 10.1039/c4cc07048h. PubMed PMID: 25308838.

165: Zhu YJ, Chen F. pH-responsive drug-delivery systems. Chem Asian J. 2015

Feb;10(2):284-305. doi: 10.1002/asia.201402715. Epub 2014 Oct 9. PubMed PMID:

25303435.

166: Bagherifam S, Skjeldal FM, Griffiths G, Mælandsmo GM, Engebråten O, Nyström

B, Hasirci V, Hasirci N. pH-responsive nano carriers for doxorubicin delivery.

Pharm Res. 2015 Apr;32(4):1249-63. doi: 10.1007/s11095-014-1530-0. Epub 2014 Oct

7. PubMed PMID: 25288014.

167: Li S, Hu K, Cao W, Sun Y, Sheng W, Li F, Wu Y, Liang XJ. pH-responsive

biocompatible fluorescent polymer nanoparticles based on phenylboronic acid for

intracellular imaging and drug delivery. Nanoscale. 2014 Nov 21;6(22):13701-9.

doi: 10.1039/c4nr04054f. PubMed PMID: 25278283.

168: Hu W, Cheng L, Cheng L, Zheng M, Lei Q, Hu Z, Xu M, Qiu L, Chen D. Redox and

pH-responsive poly (amidoamine) dendrimer-poly (ethylene glycol) conjugates with

disulfide linkages for efficient intracellular drug release. Colloids Surf B

Biointerfaces. 2014 Nov 1;123:254-63. doi: 10.1016/j.colsurfb.2014.09.024. Epub

2014 Sep 22. PubMed PMID: 25277289.

169: Morse AJ, Madsen J, Growney DJ, Armes SP, Mills P, Swart R. Microgel

colloidosomes based on pH-responsive poly(tert-butylaminoethyl methacrylate)

latexes. Langmuir. 2014 Oct 28;30(42):12509-19. doi: 10.1021/la5033674. Epub 2014

Oct 14. PubMed PMID: 25264579.

170: Manchun S, Cheewatanakornkool K, Dass CR, Sriamornsak P. Novel pH-responsive

dextrin nanogels for doxorubicin delivery to cancer cells with reduced

cytotoxicity to cardiomyocytes and stem cells. Carbohydr Polym. 2014 Dec

19;114:78-86. doi: 10.1016/j.carbpol.2014.08.002. Epub 2014 Aug 10. PubMed PMID:

25263867.

171: Xu Y, Wang L, Li YK, Wang CQ. Oxidation and pH responsive nanoparticles

based on ferrocene-modified chitosan oligosaccharide for 5-fluorouracil delivery.

Carbohydr Polym. 2014 Dec 19;114:27-35. doi: 10.1016/j.carbpol.2014.08.003. Epub

2014 Aug 10. PubMed PMID: 25263860.

172: Pan D, She W, Guo C, Luo K, Yi Q, Gu Z. PEGylated dendritic

diaminocyclohexyl-platinum (II) conjugates as pH-responsive drug delivery

vehicles with enhanced tumor accumulation and antitumor efficacy. Biomaterials.

2014 Dec;35(38):10080-92. doi: 10.1016/j.biomaterials.2014.09.006. Epub 2014 Sep

26. PubMed PMID: 25263685.

173: Lu KY, Lin CW, Hsu CH, Ho YC, Chuang EY, Sung HW, Mi FL. FRET-based

dual-emission and pH-responsive nanocarriers for enhanced delivery of protein

across intestinal epithelial cell barrier. ACS Appl Mater Interfaces. 2014 Oct

22;6(20):18275-89. doi: 10.1021/am505441p. Epub 2014 Oct 13. PubMed PMID:

25260022.

174: Lee CS, Na K. Photochemically triggered cytosolic drug delivery using

pH-responsive hyaluronic acid nanoparticles for light-induced cancer therapy.

Biomacromolecules. 2014 Nov 10;15(11):4228-38. doi: 10.1021/bm501258s. Epub 2014

Oct 7. PubMed PMID: 25251731.

175: Joseph D, Tyagi N, Geckeler C, E Geckeler K. Protein-coated pH-responsive

gold nanoparticles: Microwave-assisted synthesis and surface charge-dependent

anticancer activity. Beilstein J Nanotechnol. 2014 Sep 4;5:1452-62. doi:

10.3762/bjnano.5.158. eCollection 2014. PubMed PMID: 25247128; PubMed Central

PMCID: PMC4168932.

176: Cevik O, Gidon D, Kizilel S. Visible-light-induced synthesis of

pH-responsive composite hydrogels for controlled delivery of the anticonvulsant

drug pregabalin. Acta Biomater. 2015 Jan;11:151-61. doi:

10.1016/j.actbio.2014.09.018. Epub 2014 Sep 19. PubMed PMID: 25242648.

177: Tian Z, Yang C, Wang W, Yuan Z. Shieldable tumor targeting based on pH

responsive self-assembly/disassembly of gold nanoparticles. ACS Appl Mater

Interfaces. 2014 Oct 22;6(20):17865-76. doi: 10.1021/am5045339. Epub 2014 Sep 30.

PubMed PMID: 25233129.

178: Zhang P, Wu T, Kong JL. In situ monitoring of intracellular controlled drug

release from mesoporous silica nanoparticles coated with pH-responsive

charge-reversal polymer. ACS Appl Mater Interfaces. 2014 Oct 22;6(20):17446-53.

doi: 10.1021/am5059519. Epub 2014 Oct 3. PubMed PMID: 25231082.

179: Zhang HY, Sun YF, Sun YL, Zhou M. pH-responsive mesoporous silica

nanocarriers based on layer-by-layer self-assembly. Biomed Mater Eng.

2014;24(6):2211-8. doi: 10.3233/BME-141033. PubMed PMID: 25226920.

180: Alba M, Formentín P, Ferré-Borrull J, Pallarès J, Marsal LF. pH-responsive

drug delivery system based on hollow silicon dioxide micropillars coated with

polyelectrolyte multilayers. Nanoscale Res Lett. 2014 Aug 21;9(1):411. doi:

10.1186/1556-276X-9-411. eCollection 2014. PubMed PMID: 25221455; PubMed Central

PMCID: PMC4151279.

181: Ghosh M, Brahmachari S, Das PK. pH-Responsive single walled carbon nanotube

dispersion for target specific release of doxorubicin to cancer cells. Macromol

Biosci. 2014 Dec;14(12):1795-806. doi: 10.1002/mabi.201400290. Epub 2014 Sep 11.

PubMed PMID: 25212998.

182: Bogomolova A, Keller S, Klingler J, Sedlak M, Rak D, Sturcova A, Hruby M,

Stepanek P, Filippov SK. Self-assembly thermodynamics of pH-responsive

amino-acid-based polymers with a nonionic surfactant. Langmuir. 2014 Sep

30;30(38):11307-18. doi: 10.1021/la5031262. Epub 2014 Sep 18. PubMed PMID:

25192406.

183: Calcagnile P, Blasi L, Rizzi F, Qualtieri A, Athanassiou A, Gogolides E, De

Vittorio M. Parylene C surface functionalization and patterning with

pH-responsive microgels. ACS Appl Mater Interfaces. 2014 Sep 24;6(18):15708-15.

doi: 10.1021/am502467y. Epub 2014 Sep 3. PubMed PMID: 25184311.

184: Yao X, Chen L, Chen X, He C, Zhang J, Chen X. Metallo-supramolecular

nanogels for intracellular pH-responsive drug release. Macromol Rapid Commun.

2014 Oct;35(19):1697-705. doi: 10.1002/marc.201400291. Epub 2014 Sep 1. PubMed

PMID: 25179405.

185: de Oliveira VM, de Carvalho SJ. Adsorption of pH-responsive polyelectrolyte

chains onto spherical macroions. Eur Phys J E Soft Matter. 2014 Aug;37(8):29.

doi: 10.1140/epje/i2014-14075-4. Epub 2014 Aug 27. PubMed PMID: 25160485.

186: Xiong Q, Zhang M, Zhang Z, Shen W, Liu L, Zhang Q. Anti-tumor drug delivery

system based on cyclodextrin-containing pH-responsive star polymer: in vitro and

in vivo evaluation. Int J Pharm. 2014 Oct 20;474(1-2):232-40. doi:

10.1016/j.ijpharm.2014.08.018. Epub 2014 Aug 19. PubMed PMID: 25149124.

187: Li SY, Liu LH, Jia HZ, Qiu WX, Rong L, Cheng H, Zhang XZ. A pH-responsive

prodrug for real-time drug release monitoring and targeted cancer therapy. Chem

Commun (Camb). 2014 Oct 14;50(80):11852-5. doi: 10.1039/c4cc05008h. PubMed PMID:

25145493.

188: Das D, Pal S. Dextrin/poly (HEMA): pH responsive porous hydrogel for

controlled release of ciprofloxacin. Int J Biol Macromol. 2015 Jan;72:171-8. doi:

10.1016/j.ijbiomac.2014.08.007. Epub 2014 Aug 17. PubMed PMID: 25138539.

189: Beun LH, Storm IM, Werten MW, de Wolf FA, Cohen Stuart MA, de Vries R. From

micelles to fibers: balancing self-assembling and random coiling domains in

pH-responsive silk-collagen-like protein-based polymers. Biomacromolecules. 2014

Sep 8;15(9):3349-57. doi: 10.1021/bm500826y. Epub 2014 Aug 27. PubMed PMID:

25133990; PubMed Central PMCID: PMC4260859.

190: Vazhayal L, Talasila S, Abdul Azeez PM, Solaiappan A. Mesochanneled

hierarchically porous aluminosiloxane aerogel microspheres as a stable support

for pH-responsive controlled drug release. ACS Appl Mater Interfaces. 2014 Sep

10;6(17):15564-74. doi: 10.1021/am504422z. Epub 2014 Aug 22. PubMed PMID:

25130541.

191: Chen YH, Chang SH, Wang IJ, Young TH. The mechanism for keratinocyte

detaching from pH-responsive chitosan. Biomaterials. 2014 Nov;35(34):9247-54.

doi: 10.1016/j.biomaterials.2014.07.025. Epub 2014 Aug 14. PubMed PMID: 25129571.

192: Gao Y, Ahiabu A, Serpe MJ. Controlled drug release from the

aggregation-disaggregation behavior of pH-responsive microgels. ACS Appl Mater

Interfaces. 2014 Aug 27;6(16):13749-56. doi: 10.1021/am503200p. Epub 2014 Aug 13.

PubMed PMID: 25118818.

193: Wen X, Tang L, Li B. Metallogel template fabrication of pH-responsive

copolymer nanowires loaded with silver nanoparticles and their photocatalytic

degradation of methylene blue. Chem Asian J. 2014 Oct;9(10):2975-83. doi:

10.1002/asia.201402575. Epub 2014 Aug 11. PubMed PMID: 25112607.

194: Sedlacek O, Kucka J, Mattova J, Parizek M, Studenovsky M, Zadinova M,

Pouckova P, Hruby M. Multistage-targeted pH-responsive polymer conjugate of Auger

electron emitter: optimized design and in vivo activity. Eur J Pharm Sci. 2014

Oct 15;63:216-25. doi: 10.1016/j.ejps.2014.07.012. Epub 2014 Aug 7. PubMed PMID:

25110352.

195: Lu BQ, Zhu YJ, Chen F, Qi C, Zhao XY, Zhao J. Core-shell hollow microspheres

of magnetic iron oxide@amorphous calcium phosphate: synthesis using adenosine

5'-triphosphate and application in pH-responsive drug delivery. Chem Asian J.

2014 Oct;9(10):2908-14. doi: 10.1002/asia.201402319. Epub 2014 Aug 5. PubMed

PMID: 25100227.

196: Sudre G, Hourdet D, Creton C, Cousin F, Tran Y. Probing pH-responsive

interactions between polymer brushes and hydrogels by neutron reflectivity.

Langmuir. 2014 Aug 19;30(32):9700-6. doi: 10.1021/la501568p. Epub 2014 Aug 6.

PubMed PMID: 25099624.

197: Pennakalathil J, Jahja E, Ozdemir ES, Konu O, Tuncel D. Red emitting,

cucurbituril-capped, pH-responsive conjugated oligomer-based nanoparticles for

drug delivery and cellular imaging. Biomacromolecules. 2014 Sep 8;15(9):3366-74.

doi: 10.1021/bm500839j. Epub 2014 Aug 7. PubMed PMID: 25075758.

198: Kang Y, Ha W, Liu YQ, Ma Y, Fan MM, Ding LS, Zhang S, Li BJ. pH-responsive

polymer-drug conjugates as multifunctional micelles for cancer-drug delivery.

Nanotechnology. 2014 Aug 22;25(33):335101. doi: 10.1088/0957-4484/25/33/335101.

Epub 2014 Jul 30. PubMed PMID: 25073730.

199: Yang C, Guo W, Cui L, An N, Zhang T, Lin H, Qu F. pH-responsive magnetic

core-shell nanocomposites for drug delivery. Langmuir. 2014 Aug

19;30(32):9819-27. doi: 10.1021/la501833u. Epub 2014 Aug 6. PubMed PMID:

25073728.

200: Kurland NE, Ragland RB, Zhang A, Moustafa ME, Kundu SC, Yadavalli VK. pH

responsive poly amino-acid hydrogels formed via silk sericin templating. Int J

Biol Macromol. 2014 Sep;70:565-71. doi: 10.1016/j.ijbiomac.2014.07.036. Epub 2014

Jul 27. PubMed PMID: 25073107.

201: Dunderdale GJ, Urata C, Miranda DF, Hozumi A. Large-scale and

environmentally friendly synthesis of pH-responsive oil-repellent polymer brush

surfaces under ambient conditions. ACS Appl Mater Interfaces. 2014 Aug

13;6(15):11864-8. doi: 10.1021/am503931j. Epub 2014 Aug 1. PubMed PMID: 25072278.

202: Car A, Baumann P, Duskey JT, Chami M, Bruns N, Meier W. pH-responsive

PDMS-b-PDMAEMA micelles for intracellular anticancer drug delivery.

Biomacromolecules. 2014 Sep 8;15(9):3235-45. doi: 10.1021/bm500919z. Epub 2014

Aug 7. PubMed PMID: 25068477.

203: Chen CY, Wang HL. Dual thermo- and pH-responsive zwitterionic sulfobataine

copolymers for oral delivery system. Macromol Rapid Commun. 2014

Sep;35(17):1534-40. doi: 10.1002/marc.201400161. Epub 2014 Jul 19. PubMed PMID:

25042406.

204: Li S, Wu W, Xiu K, Xu F, Li Z, Li J. Doxorubicin loaded pH-responsive

micelles capable of rapid intracellular drug release for potential tumor therapy.

J Biomed Nanotechnol. 2014 Aug;10(8):1480-9. PubMed PMID: 25016648.

205: Wang Y, Li D, Wang H, Chen Y, Han H, Jin Q, Ji J. pH responsive

supramolecular prodrug micelles based on cucurbit[8]uril for intracellular drug

delivery. Chem Commun (Camb). 2014 Aug 25;50(66):9390-2. doi: 10.1039/c4cc03978e.

PubMed PMID: 25005141.

206: Wei H, Shi N, Zhang J, Guan Y, Zhang J, Wan X. pH-responsive

inorganic-organic hybrid supramolecular hydrogels with jellyfish-like switchable

chromic luminescence. Chem Commun (Camb). 2014 Aug 25;50(66):9333-5. doi:

10.1039/c4cc04000g. PubMed PMID: 25001843.

207: Song E, Han W, Li C, Cheng D, Li L, Liu L, Zhu G, Song Y, Tan W. Hyaluronic

acid-decorated graphene oxide nanohybrids as nanocarriers for targeted and

pH-responsive anticancer drug delivery. ACS Appl Mater Interfaces. 2014 Aug

13;6(15):11882-90. doi: 10.1021/am502423r. Epub 2014 Jul 16. PubMed PMID:

25000539.

208: Jang SW, Lee JW, Ryu DS, Son M, Kang MJ. Design of pH-responsive alginate

raft formulation of risedronate for reduced esophageal irritation. Int J Biol

Macromol. 2014 Sep;70:174-8. doi: 10.1016/j.ijbiomac.2014.06.048. Epub 2014 Jul

1. PubMed PMID: 24995633.

209: Chiang WL, Hu YC, Liu HY, Hsiao CW, Sureshbabu R, Yang CM, Chung MF, Chia

WT, Sung HW. Injectable microbeads with a thermo-responsive shell and a

pH-responsive core as a dual-switch-controlled release system. Small. 2014 Oct

29;10(20):4100-5. doi: 10.1002/smll.201400842. Epub 2014 Jun 30. PubMed PMID:

24976002.

210: Setty CM, Deshmukh AS, Badiger AM. Hydrolyzed polyacrylamide grafted maize

starch based microbeads: application in pH responsive drug delivery. Int J Biol

Macromol. 2014 Sep;70:1-9. doi: 10.1016/j.ijbiomac.2014.06.027. Epub 2014 Jun 24.

PubMed PMID: 24971555.

211: Krieg A, Arici E, Windhab N, Schattka JH, Schubert S, Schubert US. Toward

pH-responsive coating materials--high-throughput study of (meth)acrylic

copolymers. ACS Comb Sci. 2014 Aug 11;16(8):386-92. doi: 10.1021/co500011c. Epub

2014 Jul 10. PubMed PMID: 24964068.

212: Mohammed AA, Burger SK, Ayers PW. Drug release by pH-responsive molecular

tweezers: atomistic details from molecular modeling. J Comput Chem. 2014 Aug

5;35(21):1545-51. doi: 10.1002/jcc.23652. Epub 2014 Jun 25. PubMed PMID:

24962869.

213: Mooney R, Weng Y, Garcia E, Bhojane S, Smith-Powell L, Kim SU, Annala AJ,

Aboody KS, Berlin JM. Conjugation of pH-responsive nanoparticles to neural stem

cells improves intratumoral therapy. J Control Release. 2014 Oct 10;191:82-9.

doi: 10.1016/j.jconrel.2014.06.015. Epub 2014 Jun 18. PubMed PMID: 24952368;

PubMed Central PMCID: PMC4156897.

214: Duan J, Freeling JP, Koehn J, Shu C, Ho RJ. Evaluation of atazanavir and

darunavir interactions with lipids for developing pH-responsive anti-HIV drug

combination nanoparticles. J Pharm Sci. 2014 Aug;103(8):2520-9. doi:

10.1002/jps.24046. Epub 2014 Jun 19. PubMed PMID: 24948204; PubMed Central PMCID:

PMC4349556.

215: Xiao L, Isner A, Waldrop K, Saad A, Takigawa D, Bhattacharyya D. Development

of Bench and Full-Scale Temperature and pH Responsive Functionalized PVDF

Membranes with Tunable Properties. J Memb Sci. 2014 May 1;457:39-49. PubMed PMID:

24944434; PubMed Central PMCID: PMC4058347.

216: FitzGerald PA, Gupta S, Wood K, Perrier S, Warr GG. Temperature- and

pH-responsive micelles with collapsible poly(N-isopropylacrylamide) headgroups.

Langmuir. 2014 Jul 15;30(27):7986-92. doi: 10.1021/la501861t. Epub 2014 Jul 1.

PubMed PMID: 24941305.

217: Lin W, Nie S, Xiong D, Guo X, Wang J, Zhang L. pH-responsive micelles based

on (PCL)2(PDEA-b-PPEGMA)2 miktoarm polymer: controlled synthesis,

characterization, and application as anticancer drug carrier. Nanoscale Res Lett.

2014 May 18;9(1):243. doi: 10.1186/1556-276X-9-243. eCollection 2014. PubMed

PMID: 24936159; PubMed Central PMCID: PMC4046072.

218: Unsoy G, Khodadust R, Yalcin S, Mutlu P, Gunduz U. Synthesis of Doxorubicin

loaded magnetic chitosan nanoparticles for pH responsive targeted drug delivery.

Eur J Pharm Sci. 2014 Oct 1;62:243-50. doi: 10.1016/j.ejps.2014.05.021. Epub 2014

Jun 12. PubMed PMID: 24931189.

219: Yao X, Chen L, Chen X, He C, Zheng H, Chen X. Intercellular pH-responsive

histidine modified dextran-g-cholesterol micelle for anticancer drug delivery.

Colloids Surf B Biointerfaces. 2014 Sep 1;121:36-43. doi:

10.1016/j.colsurfb.2014.05.032. Epub 2014 May 28. PubMed PMID: 24929531.

220: Yang CH, Wang CY, Grumezescu AM, Wang AH, Hsiao CJ, Chen ZY, Huang KS.

Core-shell structure microcapsules with dual pH-responsive drug release function.

Electrophoresis. 2014 Sep;35(18):2673-80. doi: 10.1002/elps.201400210. Epub 2014

Jul 29. PubMed PMID: 24917513.

221: Ngwuluka NC, Choonara YE, Kumar P, du Toit LC, Khan RA, Pillay V. A novel

pH-responsive interpolyelectrolyte hydrogel complex for the oral delivery of

levodopa. Part I. IPEC modeling and synthesis. J Biomed Mater Res A. 2015

Mar;103(3):1077-84. doi: 10.1002/jbm.a.35259. Epub 2014 Jun 25. PubMed PMID:

24909427.

222: Ngwuluka NC, Choonara YE, Kumar P, du Toit LC, Khan RA, Pillay V. A novel

pH-responsive interpolyelectrolyte hydrogel complex for the oral delivery of

levodopa. Part II: characterization and formulation of an IPEC-based tablet

matrix. J Biomed Mater Res A. 2015 Mar;103(3):1085-94. doi: 10.1002/jbm.a.35258.

Epub 2014 Jun 17. PubMed PMID: 24909309.

223: Salentinig S, Phan S, Darwish TA, Kirby N, Boyd BJ, Gilbert EP.

pH-responsive micelles based on caprylic acid. Langmuir. 2014 Jul

1;30(25):7296-303. doi: 10.1021/la500835e. Epub 2014 Jun 20. PubMed PMID:

24905895.

224: Zhang J, You S, Yan S, Müllen K, Yang W, Yin M. pH-responsive self-assembly

of fluorophore-ended homopolymers. Chem Commun (Camb). 2014 Jul 18;50(56):7511-3.

doi: 10.1039/c4cc02448f. PubMed PMID: 24887322.

225: Unsoy G, Yalcin S, Khodadust R, Mutlu P, Onguru O, Gunduz U. Chitosan

magnetic nanoparticles for pH responsive Bortezomib release in cancer therapy.

Biomed Pharmacother. 2014 Jun;68(5):641-8. doi: 10.1016/j.biopha.2014.04.003.

Epub 2014 Apr 26. PubMed PMID: 24880680.

226: Shi B, Zhang H, Bi J, Dai S. Endosomal pH responsive polymers for efficient

cancer targeted gene therapy. Colloids Surf B Biointerfaces. 2014 Jul

1;119:55-65. doi: 10.1016/j.colsurfb.2014.04.005. Epub 2014 Apr 21. PubMed PMID:

24880229.

227: Yang B, Lv Y, Zhu JY, Han YT, Jia HZ, Chen WH, Feng J, Zhang XZ, Zhuo RX. A

pH-responsive drug nanovehicle constructed by reversible attachment of

cholesterol to PEGylated poly(l-lysine) via catechol-boronic acid ester

formation. Acta Biomater. 2014 Aug;10(8):3686-95. doi:

10.1016/j.actbio.2014.05.018. Epub 2014 May 27. PubMed PMID: 24879311.

228: Shahin M, Safaei-Nikouei N, Lavasanifar A. Polymeric micelles for

pH-responsive delivery of cisplatin. J Drug Target. 2014 Aug;22(7):629-37. doi:

10.3109/1061186X.2014.921925. Epub 2014 May 30. PubMed PMID: 24878378.

229: Wang QM, Gao Z, Liu S, Fan B, Kang L, Huang W, Jin M. Hybrid polymeric

micelles based on bioactive polypeptides as pH-responsive delivery systems

against melanoma. Biomaterials. 2014 Aug;35(25):7008-21. doi:

10.1016/j.biomaterials.2014.04.117. Epub 2014 May 27. PubMed PMID: 24875757.

230: Fan B, Xing Y, Zheng Y, Sun C, Liang G. pH-responsive thiolated chitosan

nanoparticles for oral low-molecular weight heparin delivery: in vitro and in

vivo evaluation. Drug Deliv. 2014 May 28:1-10. [Epub ahead of print] PubMed PMID:

24865290.

231: Rafiee E, Eavani S. pH-responsive controlled release of epirubicin from

Fe@Si-PW hybrid nanoparticles. Mater Sci Eng C Mater Biol Appl. 2014 Jun

1;39:340-3. doi: 10.1016/j.msec.2014.03.020. Epub 2014 Mar 16. PubMed PMID:

24863234.

232: Koetting MC, Peppas NA. pH-Responsive poly(itaconic

acid-co-N-vinylpyrrolidone) hydrogels with reduced ionic strength loading

solutions offer improved oral delivery potential for high isoelectric

point-exhibiting therapeutic proteins. Int J Pharm. 2014 Aug 25;471(1-2):83-91.

doi: 10.1016/j.ijpharm.2014.05.023. Epub 2014 May 20. PubMed PMID: 24853463;

PubMed Central PMCID: PMC4096305.

233: Du Z, Xiang S, Zang Y, Zhou Y, Wang C, Tang H, Jin T, Zhang X. Polyspermine

imine, a pH responsive polycationic siRNA carrier degradable to endogenous

metabolites. Mol Pharm. 2014 Oct 6;11(10):3300-6. doi: 10.1021/mp500169p. Epub

2014 Jun 2. PubMed PMID: 24846641.

234: Wu Y, Liu Z, Liang Y, Pei X, Zhou F, Xue Q. Switching fluid slippage on

pH-responsive superhydrophobic surfaces. Langmuir. 2014 Jun 10;30(22):6463-8.

doi: 10.1021/la500999k. Epub 2014 May 30. PubMed PMID: 24845303.

235: Oh NM, Oh KT, Lee ES. Development of pH-responsive poly(γ-cyclodextrin)

derivative nanoparticles. Colloids Surf B Biointerfaces. 2014 Jul 1;119:14-21.

doi: 10.1016/j.colsurfb.2014.04.017. Epub 2014 May 2. PubMed PMID: 24840748.

236: Quadir MA, Morton SW, Deng ZJ, Shopsowitz KE, Murphy RP, Epps TH 3rd,

Hammond PT. PEG-polypeptide block copolymers as pH-responsive

endosome-solubilizing drug nanocarriers. Mol Pharm. 2014 Jul 7;11(7):2420-30.

doi: 10.1021/mp500162w. Epub 2014 Jun 12. PubMed PMID: 24813025; PubMed Central

PMCID: PMC4096223.

237: Curthoys NP, Gstraunthaler G. pH-responsive, gluconeogenic renal epithelial

LLC-PK1-FBPase+cells: a versatile in vitro model to study renal proximal tubule

metabolism and function. Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F1-F11.

doi: 10.1152/ajprenal.00067.2014. Epub 2014 May 7. Review. PubMed PMID: 24808535;

PubMed Central PMCID: PMC4080158.

238: Chen J, Guo Z, Wang HB, Zhou JJ, Zhang WJ, Chen QW. Multifunctional

mesoporous nanoparticles as pH-responsive Fe(2+) reservoirs and artemisinin

vehicles for synergistic inhibition of tumor growth. Biomaterials. 2014

Aug;35(24):6498-507. doi: 10.1016/j.biomaterials.2014.04.028. Epub 2014 May 5.

PubMed PMID: 24797880.

239: Tu F, Lee D. Shape-changing and amphiphilicity-reversing Janus particles

with pH-responsive surfactant properties. J Am Chem Soc. 2014 Jul

16;136(28):9999-10006. doi: 10.1021/ja503189r. Epub 2014 Jul 1. PubMed PMID:

24791976.

240: Chung MF, Chia WT, Liu HY, Hsiao CW, Hsiao HC, Yang CM, Sung HW.

Inflammation-induced drug release by using a pH-responsive gas-generating

hollow-microsphere system for the treatment of osteomyelitis. Adv Healthc Mater.

2014 Nov;3(11):1854-61. doi: 10.1002/adhm.201400158. Epub 2014 May 2. PubMed

PMID: 24789379.

241: Tabatabaei Rezaei SJ, Abandansari HS, Nabid MR, Niknejad H. pH-responsive

unimolecular micelles self-assembled from amphiphilic hyperbranched block

copolymer for efficient intracellular release of poorly water-soluble anticancer

drugs. J Colloid Interface Sci. 2014 Jul 1;425:27-35. doi:

10.1016/j.jcis.2014.03.034. Epub 2014 Mar 25. PubMed PMID: 24776660.

242: Kumar BV, Salikolimi K, Eswaramoorthy M. Glucose- and pH-responsive

charge-reversal surfaces. Langmuir. 2014 Apr 29;30(16):4540-4. doi:

10.1021/la500407r. Epub 2014 Apr 15. PubMed PMID: 24773560.

243: Fleige E, Achazi K, Schaletzki K, Triemer T, Haag R. pH-responsive dendritic

core-multishell nanocarriers. J Control Release. 2014 Jul 10;185:99-108. doi:

10.1016/j.jconrel.2014.04.019. Epub 2014 Apr 22. PubMed PMID: 24768791.

244: Araújo M, Viveiros R, Correia TR, Correia IJ, Bonifácio VD, Casimiro T,

Aguiar-Ricardo A. Natural melanin: a potential pH-responsive drug release device.

Int J Pharm. 2014 Jul 20;469(1):140-5. doi: 10.1016/j.ijpharm.2014.04.051. Epub

2014 Apr 23. PubMed PMID: 24768404.

245: Ipuy M, Billon C, Micouin G, Samarut J, Andraud C, Bretonnière Y.

Fluorescent push-pull pH-responsive probes for ratiometric detection of

intracellular pH. Org Biomol Chem. 2014 Jun 14;12(22):3641-8. doi:

10.1039/c4ob00147h. Epub 2014 Apr 23. PubMed PMID: 24756609.

246: Ding X, Liu Y, Li J, Luo Z, Hu Y, Zhang B, Liu J, Zhou J, Cai K.

Hydrazone-bearing PMMA-functionalized magnetic nanocubes as pH-responsive drug

carriers for remotely targeted cancer therapy in vitro and in vivo. ACS Appl

Mater Interfaces. 2014 May 28;6(10):7395-407. doi: 10.1021/am500818m. Epub 2014

May 1. PubMed PMID: 24749476.

247: Feng W, Nie W, He C, Zhou X, Chen L, Qiu K, Wang W, Yin Z. Effect of

pH-responsive alginate/chitosan multilayers coating on delivery efficiency,

cellular uptake and biodistribution of mesoporous silica nanoparticles based

nanocarriers. ACS Appl Mater Interfaces. 2014 Jun 11;6(11):8447-60. doi:

10.1021/am501337s. Epub 2014 Apr 30. PubMed PMID: 24745551.

248: Yang KN, Zhang CQ, Wang W, Wang PC, Zhou JP, Liang XJ. pH-responsive

mesoporous silica nanoparticles employed in controlled drug delivery systems for

cancer treatment. Cancer Biol Med. 2014 Mar;11(1):34-43. doi:

10.7497/j.issn.2095-3941.2014.01.003. Review. PubMed PMID: 24738037; PubMed

Central PMCID: PMC3969802.

249: Chiang YT, Lo CL. pH-responsive polymer-liposomes for intracellular drug

delivery and tumor extracellular matrix switched-on targeted cancer therapy.

Biomaterials. 2014 Jul;35(20):5414-24. doi: 10.1016/j.biomaterials.2014.03.046.

Epub 2014 Apr 4. PubMed PMID: 24709521.

250: Keller S, Wilson JT, Patilea GI, Kern HB, Convertine AJ, Stayton PS. Neutral

polymer micelle carriers with pH-responsive, endosome-releasing activity modulate

antigen trafficking to enhance CD8(+) T cell responses. J Control Release. 2014

Oct 10;191:24-33. doi: 10.1016/j.jconrel.2014.03.041. Epub 2014 Mar 31. PubMed

PMID: 24698946; PubMed Central PMCID: PMC4156909.

251: Lale SV, R G A, Aravind A, Kumar DS, Koul V. AS1411 aptamer and folic acid

functionalized pH-responsive ATRP fabricated pPEGMA-PCL-pPEGMA polymeric

nanoparticles for targeted drug delivery in cancer therapy. Biomacromolecules.

2014 May 12;15(5):1737-52. doi: 10.1021/bm5001263. Epub 2014 Apr 15. PubMed PMID:

24689987.

252: Halacheva SS, Adlam DJ, Hendow EK, Freemont TJ, Hoyland J, Saunders BR.

Injectable biocompatible and biodegradable pH-responsive hollow particle gels

containing poly(acrylic acid): the effect of copolymer composition on gel

properties. Biomacromolecules. 2014 May 12;15(5):1814-27. doi: 10.1021/bm5002069.

Epub 2014 Apr 14. PubMed PMID: 24684558.

253: Mei L, He F, Zhou RQ, Wu CD, Liang R, Xie R, Ju XJ, Wang W, Chu LY. Novel

intestinal-targeted Ca-alginate-based carrier for pH-responsive protection and

release of lactic acid bacteria. ACS Appl Mater Interfaces. 2014 Apr

23;6(8):5962-70. doi: 10.1021/am501011j. Epub 2014 Apr 9. PubMed PMID: 24684476.

254: Malik B, Gupta RK, Rath G, Goyal AK. Development of pH responsive novel

emulsion adjuvant for oral immunization and in vivo evaluation. Eur J Pharm

Biopharm. 2014 Aug;87(3):589-97. doi: 10.1016/j.ejpb.2014.03.014. Epub 2014 Mar

27. PubMed PMID: 24681295.

255: Araujo JV, Davidenko N, Danner M, Cameron RE, Best SM. Novel porous

scaffolds of pH responsive chitosan/carrageenan-based polyelectrolyte complexes

for tissue engineering. J Biomed Mater Res A. 2014 Dec;102(12):4415-26. doi:

10.1002/jbm.a.35128. Epub 2014 Feb 25. PubMed PMID: 24677767.

256: Wang H, Tan B, Wang J, Li Z, Zhang S. Anion-based pH responsive ionic

liquids: design, synthesis, and reversible self-assembling structural changes in

aqueous solution. Langmuir. 2014 Apr 15;30(14):3971-8. doi: 10.1021/la500030k.

Epub 2014 Apr 4. PubMed PMID: 24673329.

257: Yu JC, Chen YL, Zhang YQ, Yao XK, Qian CG, Huang J, Zhu S, Jiang XQ, Shen

QD, Gu Z. pH-Responsive and near-infrared-emissive polymer nanoparticles for

simultaneous delivery, release, and fluorescence tracking of doxorubicin in vivo.

Chem Commun (Camb). 2014 May 11;50(36):4699-702. doi: 10.1039/c3cc49870k. PubMed

PMID: 24671329.

258: Chen CK, Wang Q, Jones CH, Yu Y, Zhang H, Law WC, Lai CK, Zeng Q, Prasad PN,

Pfeifer BA, Cheng C. Synthesis of pH-responsive chitosan nanocapsules for the

controlled delivery of doxorubicin. Langmuir. 2014 Apr 15;30(14):4111-9. doi:

10.1021/la4040485. Epub 2014 Apr 4. PubMed PMID: 24665861.

259: Feng L, Li K, Shi X, Gao M, Liu J, Liu Z. Smart pH-responsive nanocarriers

based on nano-graphene oxide for combined chemo- and photothermal therapy

overcoming drug resistance. Adv Healthc Mater. 2014 Aug;3(8):1261-71. doi:

10.1002/adhm.201300549. Epub 2014 Mar 20. PubMed PMID: 24652715.

260: Ramírez-Rodríguez GB, Iafisco M, Tampieri A, Gómez-Morales J, Delgado-López

JM. pH-responsive collagen fibrillogenesis in confined droplets induced by vapour

diffusion. J Mater Sci Mater Med. 2014 Oct;25(10):2305-12. doi:

10.1007/s10856-014-5189-1. Epub 2014 Mar 21. PubMed PMID: 24652593.

261: Hwang GH, Min KH, Lee HJ, Nam HY, Choi GH, Kim BJ, Jeong SY, Lee SC.

pH-responsive robust polymer micelles with metal-ligand coordinated core

cross-links. Chem Commun (Camb). 2014 Apr 28;50(33):4351-3. doi:

10.1039/c4cc01584c. PubMed PMID: 24643304.

262: Setty CM, Deshmukh AS, Badiger AM. Hydrolyzed polyacrylamide grafted

carboxymethylxyloglucan based microbeads for pH responsive drug delivery. Int J

Biol Macromol. 2014 Jun;67:28-36. doi: 10.1016/j.ijbiomac.2014.03.005. Epub 2014

Mar 12. PubMed PMID: 24632345.

263: Liu D, Zhang H, Herranz-Blanco B, Mäkilä E, Lehto VP, Salonen J, Hirvonen J,

Santos HA. Microfluidic assembly of monodisperse multistage pH-responsive

polymer/porous silicon composites for precisely controlled multi-drug delivery.

Small. 2014 May 28;10(10):2029-38. doi: 10.1002/smll.201303740. Epub 2014 Feb 25.

PubMed PMID: 24616278.

264: Feng N, Han G, Dong J, Wu H, Zheng Y, Wang G. Nanoparticle assembly of a

photo- and pH-responsive random azobenzene copolymer. J Colloid Interface Sci.

2014 May 1;421:15-21. doi: 10.1016/j.jcis.2014.01.036. Epub 2014 Feb 4. PubMed

PMID: 24594026.

265: Baranyai Z, Rolla GA, Negri R, Forgács A, Giovenzana GB, Tei L.

Comprehensive evaluation of the physicochemical properties of Ln(III) complexes

of aminoethyl-DO3A as pH-responsive T(1) -MRI contrast agents. Chemistry. 2014

Mar 3;20(10):2933-44. doi: 10.1002/chem.201304063. Epub 2014 Feb 7. PubMed PMID:

24590497.

266: Liu F, Lin S, Zhang Z, Hu J, Liu G, Tu Y, Yang Y, Zou H, Mo Y, Miao L.

pH-responsive nanoemulsions for controlled drug release. Biomacromolecules. 2014

Mar 10;15(3):968-77. doi: 10.1021/bm4018484. Epub 2014 Feb 26. PubMed PMID:

24527876.

267: Hong BJ, Swindell EP, Macrenaris KW, Hankins PL, Chipre AJ, Mastarone DJ,

Ahn RW, Meade TJ, O'Halloran TV, Nguyen ST. pH-Responsive Theranostic

Polymer-Caged Nanobins (PCNs): Enhanced Cytotoxicity and T (1) MRI Contrast by

Her2-Targeting. Part Part Syst Charact. 2013 Sep;30(9):770-774. PubMed PMID:

24516291; PubMed Central PMCID: PMC3916701.

268: Li Z, Yang J, Yu G, He J, Abliz Z, Huang F. Synthesis of a water-soluble

pillar[9]arene and its pH-responsive binding to paraquat. Chem Commun (Camb).

2014 Mar 18;50(22):2841-3. doi: 10.1039/c3cc49535c. Epub 2014 Feb 6. PubMed PMID:

24501738.

269: Jun C, Joo JC, Lee JH, Kim YH. Thermostabilization of glutamate

decarboxylase B from Escherichia coli by structure-guided design of its

pH-responsive N-terminal interdomain. J Biotechnol. 2014 Mar 20;174:22-8. doi:

10.1016/j.jbiotec.2014.01.020. Epub 2014 Jan 27. PubMed PMID: 24480573.

270: Pourjavadi A, Hosseini SH, Alizadeh M, Bennett C. Magnetic pH-responsive

nanocarrier with long spacer length and high colloidal stability for controlled

delivery of doxorubicin. Colloids Surf B Biointerfaces. 2014 Apr 1;116:49-54.

doi: 10.1016/j.colsurfb.2013.12.048. Epub 2013 Dec 30. PubMed PMID: 24441180.

271: Yu J, Deng H, Xie F, Chen W, Zhu B, Xu Q. The potential of pH-responsive

PEG-hyperbranched polyacylhydrazone micelles for cancer therapy. Biomaterials.

2014 Mar;35(9):3132-44. doi: 10.1016/j.biomaterials.2013.12.074. Epub 2014 Jan

15. PubMed PMID: 24439411.

272: Yang C, Guo W, Cui L, Xiang D, Cai K, Lin H, Qu F. pH-responsive

controlled-release system based on mesoporous bioglass materials capped with

mineralized hydroxyapatite. Mater Sci Eng C Mater Biol Appl. 2014 Mar

1;36:237-43. doi: 10.1016/j.msec.2013.12.006. Epub 2013 Dec 16. PubMed PMID:

24433909.

273: Alswieleh AM, Cheng N, Leggett GJ, Armes SP. Spatial control over

cross-linking dictates the pH-responsive behavior of

poly(2-(tert-butylamino)ethyl methacrylate) brushes. Langmuir. 2014 Feb

11;30(5):1391-400. doi: 10.1021/la403666y. Epub 2014 Jan 28. PubMed PMID:

24417283; PubMed Central PMCID: PMC4190050.

274: Sanchez-Sanchez A, Fulton DA, Pomposo JA. pH-responsive single-chain polymer

nanoparticles utilising dynamic covalent enamine bonds. Chem Commun (Camb). 2014

Feb 21;50(15):1871-4. doi: 10.1039/c3cc48733d. Epub 2014 Jan 9. PubMed PMID:

24401844.

275: Zhang X, Liu B, Yang Z, Zhang C, Li H, Luo X, Luo H, Gao D, Jiang Q, Liu J,

Jiang Z. Micelles of enzymatically synthesized PEG-poly(amine-co-ester) block

copolymers as pH-responsive nanocarriers for docetaxel delivery. Colloids Surf B

Biointerfaces. 2014 Mar 1;115:349-58. doi: 10.1016/j.colsurfb.2013.12.029. Epub

2013 Dec 24. PubMed PMID: 24398083.

276: Zhang Q, Zhang L, Wang P, Du S. Coordinate bonding strategy for molecularly

imprinted hydrogels: toward pH-responsive doxorubicin delivery. J Pharm Sci. 2014

Feb;103(2):643-51. doi: 10.1002/jps.23838. Epub 2014 Jan 6. PubMed PMID:

24395706.

277: Liang S, Zhao Y, Adronov A. Selective and reversible noncovalent

functionalization of single-walled carbon nanotubes by a pH-responsive vinylogous

tetrathiafulvalene-fluorene copolymer. J Am Chem Soc. 2014 Jan 22;136(3):970-7.

doi: 10.1021/ja409918n. Epub 2014 Jan 9. PubMed PMID: 24369733.

278: Hong W, Chen D, Jia L, Gu J, Hu H, Zhao X, Qiao M. Thermo- and pH-responsive

copolymers based on PLGA-PEG-PLGA and poly(L-histidine): synthesis and in vitro

characterization of copolymer micelles. Acta Biomater. 2014 Mar;10(3):1259-71.

doi: 10.1016/j.actbio.2013.12.033. Epub 2013 Dec 21. PubMed PMID: 24365708.

279: Qiu L, Li Z, Qiao M, Long M, Wang M, Zhang X, Tian C, Chen D. Self-assembled

pH-responsive hyaluronic acid-g-poly((L)-histidine) copolymer micelles for

targeted intracellular delivery of doxorubicin. Acta Biomater. 2014

May;10(5):2024-35. doi: 10.1016/j.actbio.2013.12.025. Epub 2013 Dec 21. PubMed

PMID: 24365705.

280: Gao X, Cao Y, Song X, Zhang Z, Zhuang X, He C, Chen X. Biodegradable,

pH-responsive carboxymethyl cellulose/poly(acrylic acid) hydrogels for oral

insulin delivery. Macromol Biosci. 2014 Apr;14(4):565-75. doi:

10.1002/mabi.201300384. Epub 2013 Dec 19. PubMed PMID: 24357554.

281: Wang C, Wang C, Xu L, Cheng H, Lin Q, Zhang C. Protein-directed synthesis of

pH-responsive red fluorescent copper nanoclusters and their applications in

cellular imaging and catalysis. Nanoscale. 2014;6(3):1775-81. doi:

10.1039/c3nr04835g. PubMed PMID: 24352741.

282: Nakagawa A, Hisamatsu Y, Moromizato S, Kohno M, Aoki S. Synthesis and

photochemical properties of pH responsive tris-cyclometalated iridium(III)

complexes that contain a pyridine ring on the 2-phenylpyridine ligand. Inorg

Chem. 2014 Jan 6;53(1):409-22. doi: 10.1021/ic402387b. Epub 2013 Dec 16. PubMed

PMID: 24341415.

283: Chen Y, Ai K, Liu Y, Lu L. Tailor-made charge-conversional nanocomposite for

pH-responsive drug delivery and cell imaging. ACS Appl Mater Interfaces. 2014 Jan

8;6(1):655-63. doi: 10.1021/am404761h. Epub 2013 Dec 12. PubMed PMID: 24308443.

284: Nowag S, Haag R. pH-responsive micro- and nanocarrier systems. Angew Chem

Int Ed Engl. 2014 Jan 3;53(1):49-51. doi: 10.1002/anie.201308619. Epub 2013 Dec

4. PubMed PMID: 24306995.

285: Giardiello M, Botta M, Lowe MP. pH-responsive lanthanide complexes based on

reversible ligation of a diphenylphosphinamide. Inorg Chem. 2013 Dec

16;52(24):14264-9. doi: 10.1021/ic402205j. Epub 2013 Dec 4. PubMed PMID:

24304151.

286: Singh B, Sharma V. Influence of polymer network parameters of tragacanth

gum-based pH responsive hydrogels on drug delivery. Carbohydr Polym. 2014 Jan

30;101:928-40. doi: 10.1016/j.carbpol.2013.10.022. Epub 2013 Oct 16. PubMed PMID:

24299858.

287: Spizzirri UG, Cirillo G, Curcio M, Picci N, Iemma F. Flavonoid-based

pH-responsive hydrogels as carrier of unstable drugs in oxidative conditions.

Pharm Dev Technol. 2015 May;20(3):288-96. doi: 10.3109/10837450.2013.862261. Epub

2013 Dec 2. PubMed PMID: 24289106.

288: Li L, Xu Y, Milligan I, Fu L, Franckowiak EA, Du W. Synthesis of highly

pH-responsive glucose poly(orthoester). Angew Chem Int Ed Engl. 2013 Dec

16;52(51):13699-702. doi: 10.1002/anie.201306391. Epub 2013 Nov 29. PubMed PMID:

24288204.

289: Jiang J, Xie J, Ma B, Bartlett DE, Xu A, Wang CH. Mussel-inspired

protein-mediated surface functionalization of electrospun nanofibers for

pH-responsive drug delivery. Acta Biomater. 2014 Mar;10(3):1324-32. doi:

10.1016/j.actbio.2013.11.012. Epub 2013 Nov 25. PubMed PMID: 24287161; PubMed

Central PMCID: PMC3946753.

290: Kumar S, Acharya R, Chatterji U, De P. Side-chain amino-acid-based

pH-responsive self-assembled block copolymers for drug delivery and gene

transfer. Langmuir. 2013 Dec 10;29(49):15375-85. doi: 10.1021/la403819g. Epub

2013 Dec 2. PubMed PMID: 24274731.

291: Cheng Z, Du M, Lai H, Du Y, Zhang N, Sun K. Selective transportation of

microdroplets assisted by a superhydrophobic surface with pH-responsive adhesion.

Chem Asian J. 2013 Dec;8(12):3200-6. doi: 10.1002/asia.201300941. Epub 2013 Sep

20. PubMed PMID: 24273121.

292: Zhao G, Wang J, Peng X, Li Y, Yuan X, Ma Y. Facile solvothermal synthesis of

mesostructured Fe3O4/chitosan nanoparticles as delivery vehicles for

pH-responsive drug delivery and magnetic resonance imaging contrast agents. Chem

Asian J. 2014 Feb;9(2):546-53. doi: 10.1002/asia.201301072. Epub 2013 Nov 20.

PubMed PMID: 24259489.

293: Liang J, Wu WL, Xu XD, Zhuo RX, Zhang XZ. pH responsive micelle

self-assembled from a new amphiphilic peptide as anti-tumor drug carrier.

Colloids Surf B Biointerfaces. 2014 Feb 1;114:398-403. doi:

10.1016/j.colsurfb.2013.10.037. Epub 2013 Nov 1. PubMed PMID: 24257687.

294: Morse AJ, Armes SP, Mills P, Swart R. Stopped-flow kinetics of pH-responsive

polyamine latexes: how fast is the latex-to-microgel transition? Langmuir. 2013

Dec 10;29(49):15209-16. doi: 10.1021/la403626s. Epub 2013 Nov 22. PubMed PMID:

24251539.

295: Tian H, Guo Z, Lin L, Jiao Z, Chen J, Gao S, Zhu X, Chen X. pH-responsive

zwitterionic copolypeptides as charge conversional shielding system for gene

carriers. J Control Release. 2014 Jan 28;174:117-25. doi:

10.1016/j.jconrel.2013.11.008. Epub 2013 Nov 14. PubMed PMID: 24240012.

296: Chen L, Chen T, Fang W, Wen Y, Lin S, Lin J, Cai C. Synthesis and

pH-responsive "schizophrenic" aggregation of a linear-dendron-like polyampholyte

based on oppositely charged polypeptides. Biomacromolecules. 2013 Dec

9;14(12):4320-30. doi: 10.1021/bm401215w. Epub 2013 Nov 20. PubMed PMID:

24219355.

297: Shi J, Liu Y, Wang L, Gao J, Zhang J, Yu X, Ma R, Liu R, Zhang Z. A tumoral

acidic pH-responsive drug delivery system based on a novel photosensitizer

(fullerene) for in vitro and in vivo chemo-photodynamic therapy. Acta Biomater.

2014 Mar;10(3):1280-91. doi: 10.1016/j.actbio.2013.10.037. Epub 2013 Nov 6.

PubMed PMID: 24211343.

298: Koyamatsu Y, Hirano T, Kakizawa Y, Okano F, Takarada T, Maeda M.

pH-responsive release of proteins from biocompatible and biodegradable reverse

polymer micelles. J Control Release. 2014 Jan 10;173:89-95. doi:

10.1016/j.jconrel.2013.10.035. Epub 2013 Nov 4. PubMed PMID: 24200745.

299: Liu Y, Gao FP, Zhang D, Fan YS, Chen XG, Wang H. Molecular structural

transformation regulated dynamic disordering of supramolecular vesicles as

pH-responsive drug release systems. J Control Release. 2014 Jan 10;173:140-7.

doi: 10.1016/j.jconrel.2013.10.033. Epub 2013 Nov 1. PubMed PMID: 24188958.

300: Xiao M, Guo X, Cheng M, Ju G, Zhang Y, Shi F. pH-responsive on-off motion of

a superhydrophobic boat: towards the design of a minirobot. Small. 2014 Mar

12;10(5):859-65. doi: 10.1002/smll.201302132. Epub 2013 Oct 29. PubMed PMID:

24170424.

301: Kuan SL, Ng DY, Wu Y, Förtsch C, Barth H, Doroshenko M, Koynov K, Meier C,

Weil T. pH responsive Janus-like supramolecular fusion proteins for functional

protein delivery. J Am Chem Soc. 2013 Nov 20;135(46):17254-7. doi:

10.1021/ja4084122. Epub 2013 Nov 7. PubMed PMID: 24156787.

302: Kim KS, Park W, Hu J, Bae YH, Na K. A cancer-recognizable MRI contrast

agents using pH-responsive polymeric micelle. Biomaterials. 2014

Jan;35(1):337-43. doi: 10.1016/j.biomaterials.2013.10.004. Epub 2013 Oct 15.

PubMed PMID: 24139764.

303: Cheng M, Liu Q, Ju G, Zhang Y, Jiang L, Shi F. Bell-shaped

superhydrophilic-superhydrophobic-superhydrophilic double transformation on a

pH-responsive smart surface. Adv Mater. 2014 Jan 15;26(2):306-10. doi:

10.1002/adma.201302187. Epub 2013 Oct 7. PubMed PMID: 24123523.

304: Hu X, Wang Y, Peng B. Chitosan-capped mesoporous silica nanoparticles as

pH-responsive nanocarriers for controlled drug release. Chem Asian J. 2014

Jan;9(1):319-27. doi: 10.1002/asia.201301105. Epub 2013 Oct 2. PubMed PMID:

24115568.

305: Wang H, Yang L, Rempel GL. Preparation of pH-responsive polymer core-shell

nanospheres for delivery of hydrophobic antineoplastic drug ellipticine. Macromol

Biosci. 2014 Feb;14(2):166-72. doi: 10.1002/mabi.201300333. Epub 2013 Sep 16.

PubMed PMID: 24106137.

306: Chen D, Yu H, Sun K, Liu W, Wang H. Dual thermoresponsive and pH-responsive

self-assembled micellar nanogel for anticancer drug delivery. Drug Deliv. 2014

Jun;21(4):258-64. doi: 10.3109/10717544.2013.838717. Epub 2013 Oct 9. PubMed

PMID: 24102086.

307: Sharma S, Kaur J, Sharma G, Thakur KK, Chauhan GS, Chauhan K. Preparation

and characterization of pH-responsive guar gum microspheres. Int J Biol Macromol.

2013 Nov;62:636-41. doi: 10.1016/j.ijbiomac.2013.09.045. Epub 2013 Oct 4. PubMed

PMID: 24099940.

308: Chang S, Wu X, Li Y, Niu D, Gao Y, Ma Z, Gu J, Zhao W, Zhu W, Tian H, Shi J.

A pH-responsive hybrid fluorescent nanoprober for real time cell labeling and

endocytosis tracking. Biomaterials. 2013 Dec;34(38):10182-90. doi:

10.1016/j.biomaterials.2013.09.044. Epub 2013 Oct 1. PubMed PMID: 24095249.

309: Zhou C, Gao W, Yang K, Xu L, Ding J, Chen J, Liu M, Huang X, Wang S, Wu H. A

novel glucose/pH responsive low-molecular-weight organogel of easy recycling.

Langmuir. 2013 Nov 5;29(44):13568-75. doi: 10.1021/la4033578. Epub 2013 Oct 23.

PubMed PMID: 24093805.

310: Swiech O, Dutkiewicz P, Wójciuk K, Chmurski K, Kruszewski M, Bilewicz R.

Cyclodextrin derivatives conjugated with aromatic moieties as pH-responsive drug

carriers for anthracycline. J Phys Chem B. 2013 Oct 31;117(43):13444-50. doi:

10.1021/jp4060632. Epub 2013 Oct 18. PubMed PMID: 24079546.

311: Nechooshtan G, Elgrably-Weiss M, Altuvia S. Changes in transcriptional

pausing modify the folding dynamics of the pH-responsive RNA element. Nucleic

Acids Res. 2014 Jan;42(1):622-30. doi: 10.1093/nar/gkt868. Epub 2013 Sep 26.

PubMed PMID: 24078087; PubMed Central PMCID: PMC3874183.

312: Kotsuchibashi Y, Wang Y, Kim YJ, Ebara M, Aoyagi T, Narain R. Simple coating

with pH-responsive polymer-functionalized silica nanoparticles of mixed sizes for

controlled surface properties. ACS Appl Mater Interfaces. 2013 Oct

23;5(20):10004-10. doi: 10.1021/am403007f. Epub 2013 Oct 8. PubMed PMID:

24059283.

313: Nam J, Ha YS, Hwang S, Lee W, Song J, Yoo J, Kim S. pH-responsive gold

nanoparticles-in-liposome hybrid nanostructures for enhanced systemic tumor

delivery. Nanoscale. 2013 Nov 7;5(21):10175-8. doi: 10.1039/c3nr03698g. Epub 2013

Sep 13. PubMed PMID: 24057056.

314: Yun JM, Ganesan R, Choi JH, Kim JB. Local pH-responsive

diazoketo-functionalized photoresist for multicomponent protein patterning. ACS

Appl Mater Interfaces. 2013 Oct 23;5(20):10253-9. doi: 10.1021/am403053x. Epub

2013 Oct 7. PubMed PMID: 24053579.

315: Holley AC, Ray JG, Wan W, Savin DA, McCormick CL. Endolytic, pH-responsive

HPMA-b-(L-Glu) copolymers synthesized via sequential aqueous RAFT and

ring-opening polymerizations. Biomacromolecules. 2013 Oct 14;14(10):3793-9. doi:

10.1021/bm401205y. Epub 2013 Oct 2. PubMed PMID: 24044682.

316: Nwe K, Huang CH, Tsourkas A. Gd-labeled glycol chitosan as a pH-responsive

magnetic resonance imaging agent for detecting acidic tumor microenvironments. J

Med Chem. 2013 Oct 24;56(20):7862-9. doi: 10.1021/jm4012565. Epub 2013 Oct 3.

PubMed PMID: 24044414; PubMed Central PMCID: PMC3880625.

317: Abbaspourrad A, Datta SS, Weitz DA. Controlling release from pH-responsive

microcapsules. Langmuir. 2013 Oct 15;29(41):12697-702. doi: 10.1021/la403064f.

Epub 2013 Oct 2. PubMed PMID: 24041287.

318: Zhan P, Wang J, Wang ZG, Ding B. Engineering the pH-responsive catalytic

behavior of AuNPs by DNA. Small. 2014 Jan 29;10(2):399-406. doi:

10.1002/smll.201301931. Epub 2013 Aug 27. PubMed PMID: 24039035.

319: Gun WJ, Routh AF. Formation and characterization of pH-responsive liquid

core microcapsules. Langmuir. 2013 Oct 8;29(40):12541-8. doi: 10.1021/la403175w.

Epub 2013 Sep 23. PubMed PMID: 24003958.

320: Wang B, Guo Z. pH-responsive bidirectional oil-water separation material.

Chem Commun (Camb). 2013 Oct 21;49(82):9416-8. doi: 10.1039/c3cc45566a. PubMed

PMID: 24002324.

321: Lay CL, Kumar JN, Liu CK, Lu X, Liu Y. A rocket-like encapsulation and

delivery system with two-stage booster layers: pH-responsive poly(methacrylic

acid)/poly(ethylene glycol) complex-coated hollow silica vesicles. Macromol Rapid

Commun. 2013 Oct;34(19):1563-8. doi: 10.1002/marc.201300529. Epub 2013 Aug 29.

PubMed PMID: 23996916.

322: Thamphiwatana S, Fu V, Zhu J, Lu D, Gao W, Zhang L. Nanoparticle-stabilized

liposomes for pH-responsive gastric drug delivery. Langmuir. 2013 Oct

1;29(39):12228-33. doi: 10.1021/la402695c. Epub 2013 Sep 16. PubMed PMID:

23987129; PubMed Central PMCID: PMC4059759.

323: Hwang JH, Choi CW, Kim HW, Kim do H, Kwak TW, Lee HM, Kim CH, Chung CW,

Jeong YI, Kang DH. Dextran-b-poly(L-histidine) copolymer nanoparticles for

ph-responsive drug delivery to tumor cells. Int J Nanomedicine. 2013;8:3197-207.

doi: 10.2147/IJN.S49459. Epub 2013 Aug 21. PubMed PMID: 23986636; PubMed Central

PMCID: PMC3754766.

324: Yang B, Jia H, Wang X, Chen S, Zhang X, Zhuo R, Feng J. Self-assembled

vehicle construction via boronic acid coupling and host-guest interaction for

serum-tolerant DNA transport and pH-responsive drug delivery. Adv Healthc Mater.

2014 Apr;3(4):596-608. doi: 10.1002/adhm.201300162. Epub 2013 Aug 26. PubMed

PMID: 23983152.

325: Yu H, Xu Z, Chen X, Xu L, Yin Q, Zhang Z, Li Y. Reversal of lung cancer

multidrug resistance by pH-responsive micelleplexes mediating co-delivery of

siRNA and paclitaxel. Macromol Biosci. 2014 Jan;14(1):100-9. doi:

10.1002/mabi.201300282. Epub 2013 Aug 21. PubMed PMID: 23966347.

326: Hu J, Miura S, Na K, Bae YH. pH-responsive and charge shielded cationic

micelle of poly(L-histidine)-block-short branched PEI for acidic cancer

treatment. J Control Release. 2013 Nov 28;172(1):69-76. doi:

10.1016/j.jconrel.2013.08.007. Epub 2013 Aug 14. PubMed PMID: 23954370.

327: Zhang G, Jia X, Liu Z, Hu J, Ma Z, Zhou F. Protein resistance and

pH-responsive controlled release from the modification of single-walled carbon

nanotubes with a double polymer layer. Macromol Biosci. 2013 Sep;13(9):1259-66.

doi: 10.1002/mabi.201300157. Epub 2013 Jul 31. PubMed PMID: 23904214.

328: Zhang Q, Tang J, Fu L, Ran R, Liu Y, Yuan M, He Q. A pH-responsive α-helical

cell penetrating peptide-mediated liposomal delivery system. Biomaterials. 2013

Oct;34(32):7980-93. doi: 10.1016/j.biomaterials.2013.07.014. Epub 2013 Jul 24.

PubMed PMID: 23891517.

329: Best JP, Neubauer MP, Javed S, Dam HH, Fery A, Caruso F. Mechanics of

pH-responsive hydrogel capsules. Langmuir. 2013 Aug 6;29(31):9814-23. doi:

10.1021/la402111v. Epub 2013 Jul 25. PubMed PMID: 23886008.

330: Kan KH, Li J, Wijesekera K, Cranston ED. Polymer-grafted cellulose

nanocrystals as pH-responsive reversible flocculants. Biomacromolecules. 2013 Sep

9;14(9):3130-9. doi: 10.1021/bm400752k. Epub 2013 Aug 2. PubMed PMID: 23865631.

331: Jin N, Morin EA, Henn DM, Cao Y, Woodcock JW, Tang S, He W, Zhao B. Agarose

hydrogels embedded with pH-responsive diblock copolymer micelles for triggered

release of substances. Biomacromolecules. 2013 Aug 12;14(8):2713-23. doi:

10.1021/bm4005639. Epub 2013 Jul 12. PubMed PMID: 23815070; PubMed Central PMCID:

PMC3773184.

332: Rauch S, Uhlmann P, Eichhorn KJ. In situ spectroscopic ellipsometry of

pH-responsive polymer brushes on gold substrates. Anal Bioanal Chem. 2013

Nov;405(28):9061-9. doi: 10.1007/s00216-013-7090-z. Epub 2013 Jun 28. PubMed

PMID: 23812852.

333: Chen L, Li L, Zhang L, Xing S, Wang T, Wang YA, Wang C, Su Z. Designed

fabrication of unique eccentric mesoporous silica nanocluster-based core-shell

nanostructures for pH-responsive drug delivery. ACS Appl Mater Interfaces. 2013

Aug 14;5(15):7282-90. doi: 10.1021/am401627u. Epub 2013 Jul 17. PubMed PMID:

23808730.

334: Duan Q, Cao Y, Li Y, Hu X, Xiao T, Lin C, Pan Y, Wang L. pH-responsive

supramolecular vesicles based on water-soluble pillar[6]arene and ferrocene

derivative for drug delivery. J Am Chem Soc. 2013 Jul 17;135(28):10542-9. doi:

10.1021/ja405014r. Epub 2013 Jul 9. PubMed PMID: 23795864.

335: Vivek R, Nipun Babu V, Thangam R, Subramanian KS, Kannan S. pH-responsive

drug delivery of chitosan nanoparticles as Tamoxifen carriers for effective

anti-tumor activity in breast cancer cells. Colloids Surf B Biointerfaces. 2013

Nov 1;111:117-23. doi: 10.1016/j.colsurfb.2013.05.018. Epub 2013 May 22. PubMed

PMID: 23787278.

336: Kim HK, Thompson DH, Jang HS, Chung YJ, Van den Bossche J. pH-responsive

biodegradable assemblies containing tunable phenyl-substituted vinyl ethers for

use as efficient gene delivery vehicles. ACS Appl Mater Interfaces. 2013 Jun

26;5(12):5648-58. doi: 10.1021/am400977t. Epub 2013 Jun 17. PubMed PMID:

23772824; PubMed Central PMCID: PMC3740352.

337: Wang L, Shi J, Jia X, Liu R, Wang H, Wang Z, Li L, Zhang J, Zhang C, Zhang

Z. NIR-/pH-Responsive drug delivery of functionalized single-walled carbon

nanotubes for potential application in cancer chemo-photothermal therapy. Pharm

Res. 2013 Nov;30(11):2757-71. doi: 10.1007/s11095-013-1095-3. Epub 2013 Jun 14.

PubMed PMID: 23765399.

338: Gaspar VM, Marques JG, Sousa F, Louro RO, Queiroz JA, Correia IJ.

Biofunctionalized nanoparticles with pH-responsive and cell penetrating blocks

for gene delivery. Nanotechnology. 2013 Jul 12;24(27):275101. doi:

10.1088/0957-4484/24/27/275101. Epub 2013 Jun 13. PubMed PMID: 23759860.

339: Jiang P, Li D, Liu Y, Zhang X, Lai D. Remarkable pH-responsive polypropylene

microfiltration membrane through surface entrapment of poly(2-(diethylamino)

ethyl methacrylate)-containing macromolecules by ATRP method. J Nanosci

Nanotechnol. 2013 Mar;13(3):2339-47. PubMed PMID: 23755689.

340: Zhang S, Zhou K, Huang G, Takahashi M, Sherry AD, Gao J. A novel class of

polymeric pH-responsive MRI CEST agents. Chem Commun (Camb). 2013 Jul

21;49(57):6418-20. doi: 10.1039/c3cc42452a. PubMed PMID: 23752496; PubMed Central

PMCID: PMC3712501.

341: Dan K, Ghosh S. One-pot synthesis of an acid-labile amphiphilic triblock

copolymer and its pH-responsive vesicular assembly. Angew Chem Int Ed Engl. 2013

Jul 8;52(28):7300-5. doi: 10.1002/anie.201302722. Epub 2013 Jun 4. PubMed PMID:

23737257.

342: Rodríguez-Ruiz I, Delgado-López JM, Durán-Olivencia MA, Iafisco M, Tampieri

A, Colangelo D, Prat M, Gómez-Morales J. pH-responsive delivery of doxorubicin

from citrate-apatite nanocrystals with tailored carbonate content. Langmuir. 2013

Jul 2;29(26):8213-21. doi: 10.1021/la4008334. Epub 2013 Jun 18. PubMed PMID:

23735159.

343: Zheng Y, Hashidzume A, Harada A. pH-responsive self-assembly by molecular

recognition on a macroscopic scale. Macromol Rapid Commun. 2013 Jul

12;34(13):1062-6. doi: 10.1002/marc.201300324. Epub 2013 May 31. PubMed PMID:

23723096.

344: Liu T, Hu J, Jin Z, Jin F, Liu S. Two-photon ratiometric fluorescent mapping

of intracellular transport pathways of pH-responsive block copolymer micellar

nanocarriers. Adv Healthc Mater. 2013 Dec;2(12):1576-81. doi:

10.1002/adhm.201200436. Epub 2013 May 24. PubMed PMID: 23703785.

345: Liang W, Kwok PC, Chow MY, Tang P, Mason AJ, Chan HK, Lam JK. Formulation of

pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic

acids. Eur J Pharm Biopharm. 2014 Jan;86(1):64-73. doi:

10.1016/j.ejpb.2013.05.006. Epub 2013 May 20. PubMed PMID: 23702276; PubMed

Central PMCID: PMC3948054.

346: Li W, Wang J, Ren J, Qu X. Near-infrared- and pH-responsive system for

reversible cell adhesion using graphene/gold nanorods functionalized with i-motif

DNA. Angew Chem Int Ed Engl. 2013 Jun 24;52(26):6726-30. doi:

10.1002/anie.201302048. Epub 2013 May 21. PubMed PMID: 23696220.

347: Ma ZY, Jia X, Zhang GX, Hu JM, Zhang XL, Liu ZY, Wang HY, Zhou F.

pH-responsive controlled-release fertilizer with water retention via atom

transfer radical polymerization of acrylic acid on mussel-inspired initiator. J

Agric Food Chem. 2013 Jun 12;61(23):5474-82. doi: 10.1021/jf401102a. Epub 2013

Jun 3. PubMed PMID: 23692274.

348: Schoener CA, Peppas NA. pH-responsive hydrogels containing PMMA

nanoparticles: an analysis of controlled release of a chemotherapeutic conjugate

and transport properties. J Biomater Sci Polym Ed. 2013;24(9):1027-40. doi:

10.1080/09205063.2012.731376. Epub 2012 Oct 15. PubMed PMID: 23683036; PubMed

Central PMCID: PMC3662499.

349: Nouri FS, Wang X, Dorrani M, Karjoo Z, Hatefi A. A recombinant biopolymeric

platform for reliable evaluation of the activity of pH-responsive amphiphile

fusogenic peptides. Biomacromolecules. 2013 Jun 10;14(6):2033-40. doi:

10.1021/bm400380s. Epub 2013 May 30. PubMed PMID: 23682625.

350: Zabara A, Negrini R, Onaca-Fischer O, Mezzenga R. Perforated bicontinuous

cubic phases with pH-responsive topological channel interconnectivity. Small.

2013 Nov 11;9(21):3602-9. doi: 10.1002/smll.201300348. Epub 2013 May 16. PubMed

PMID: 23677679.

351: Takemoto H, Miyata K, Hattori S, Ishii T, Suma T, Uchida S, Nishiyama N,

Kataoka K. Acidic pH-responsive siRNA conjugate for reversible carrier stability

and accelerated endosomal escape with reduced IFNα-associated immune response.

Angew Chem Int Ed Engl. 2013 Jun 10;52(24):6218-21. doi: 10.1002/anie.201300178.

Epub 2013 Apr 29. PubMed PMID: 23630117.

352: Cheesman BT, Neilson AJ, Willott JD, Webber GB, Edmondson S, Wanless EJ.

Effect of colloidal substrate curvature on pH-responsive polyelectrolyte brush

growth. Langmuir. 2013 May 21;29(20):6131-40. doi: 10.1021/la4004092. Epub 2013

May 7. PubMed PMID: 23617419.

353: Niu J, Huang A, Xiao Y, Su Z, Li H, Ping Q, Bao X, Li S, Chen Y, Sun M.

Octreotide-mediated tumor cell uptake and intracellular pH-responsive drug

delivery of the self-assembly supramolecular nanocarrier. J Drug Target. 2013

May;21(5):415-26. doi: 10.3109/1061186X.2012.757771. Epub 2013 Apr 18. PubMed

PMID: 23597028.

354: He H, Chen S, Zhou J, Dou Y, Song L, Che L, Zhou X, Chen X, Jia Y, Zhang J,

Li S, Li X. Cyclodextrin-derived pH-responsive nanoparticles for delivery of

paclitaxel. Biomaterials. 2013 Jul;34(21):5344-58. doi:

10.1016/j.biomaterials.2013.03.068. Epub 2013 Apr 13. PubMed PMID: 23591391.

355: Singh J, Ranganathan R, Angayarkanny S, Baskar G, Mandal AB. pH-responsive

aggregation states of chiral polymerizable amphiphiles from L-tyrosine and

L-phenyl alanine in water. Langmuir. 2013 May 14;29(19):5734-41. doi:

10.1021/la4008922. Epub 2013 Apr 29. PubMed PMID: 23590729; PubMed Central PMCID:

PMC3695830.

356: Wilson JT, Keller S, Manganiello MJ, Cheng C, Lee CC, Opara C, Convertine A,

Stayton PS. pH-Responsive nanoparticle vaccines for dual-delivery of antigens and

immunostimulatory oligonucleotides. ACS Nano. 2013 May 28;7(5):3912-25. doi:

10.1021/nn305466z. Epub 2013 Apr 30. PubMed PMID: 23590591; PubMed Central PMCID:

PMC4042837.

357: Wu S, Huang X, Du X. Glucose- and pH-responsive controlled release of cargo

from protein-gated carbohydrate-functionalized mesoporous silica nanocontainers.

Angew Chem Int Ed Engl. 2013 May 17;52(21):5580-4. doi: 10.1002/anie.201300958.

Epub 2013 Apr 15. PubMed PMID: 23589488.

358: Morse AJ, Armes SP, Thompson KL, Dupin D, Fielding LA, Mills P, Swart R.

Novel Pickering emulsifiers based on pH-responsive poly(2-(diethylamino)ethyl

methacrylate) latexes. Langmuir. 2013 May 7;29(18):5466-75. doi:

10.1021/la400786a. Epub 2013 Apr 23. PubMed PMID: 23570375.

359: Victor SP, Sharma CP. Poly methacrylic acid modified CDHA nanocomposites as

potential pH responsive drug delivery vehicles. Colloids Surf B Biointerfaces.

2013 Aug 1;108:219-28. doi: 10.1016/j.colsurfb.2013.02.025. Epub 2013 Mar 6.

PubMed PMID: 23563287.

360: Gu X, Wang J, Wang Y, Wang Y, Gao H, Wu G. Layer-by-layer assembled

polyaspartamide nanocapsules for pH-responsive protein delivery. Colloids Surf B

Biointerfaces. 2013 Aug 1;108:205-11. doi: 10.1016/j.colsurfb.2013.03.007. Epub

2013 Mar 16. PubMed PMID: 23563286.

361: Sahoo B, Devi KS, Banerjee R, Maiti TK, Pramanik P, Dhara D. Thermal and pH

responsive polymer-tethered multifunctional magnetic nanoparticles for targeted

delivery of anticancer drug. ACS Appl Mater Interfaces. 2013 May;5(9):3884-93.

doi: 10.1021/am400572b. Epub 2013 Apr 23. PubMed PMID: 23551195.

362: Shi X, Wang W, Wang A. pH-responsive sodium alginate-based superporous

hydrogel generated by an anionic surfactant micelle templating. Carbohydr Polym.

2013 Apr 15;94(1):449-55. doi: 10.1016/j.carbpol.2013.01.019. Epub 2013 Jan 21.

PubMed PMID: 23544562.

363: Lu L, Zhang C, Li L, Zhou C. Reversible pH-responsive aggregates based on

the self-assembly of functionalized POSS and hyaluronic acid. Carbohydr Polym.

2013 Apr 15;94(1):444-8. doi: 10.1016/j.carbpol.2013.01.061. Epub 2013 Jan 28.

PubMed PMID: 23544561.

364: Dong DW, Xiang B, Gao W, Yang ZZ, Li JQ, Qi XR. pH-responsive complexes

using prefunctionalized polymers for synchronous delivery of doxorubicin and

siRNA to cancer cells. Biomaterials. 2013 Jul;34(20):4849-59. doi:

10.1016/j.biomaterials.2013.03.018. Epub 2013 Mar 27. PubMed PMID: 23541420.

365: Delatouche R, Denis I, Grinda M, El Bahhaj F, Baucher E, Collette F,

Héroguez V, Grégoire M, Blanquart C, Bertrand P. Design of pH responsive

clickable prodrugs applied to histone deacetylase inhibitors: a new strategy for

anticancer therapy. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt B):862-72. doi:

10.1016/j.ejpb.2013.03.006. Epub 2013 Mar 26. PubMed PMID: 23537575.

366: Nam J, La WG, Hwang S, Ha YS, Park N, Won N, Jung S, Bhang SH, Ma YJ, Cho

YM, Jin M, Han J, Shin JY, Wang EK, Kim SG, Cho SH, Yoo J, Kim BS, Kim S.

pH-responsive assembly of gold nanoparticles and "spatiotemporally concerted"

drug release for synergistic cancer therapy. ACS Nano. 2013 Apr 23;7(4):3388-402.

doi: 10.1021/nn400223a. Epub 2013 Apr 8. PubMed PMID: 23530622.

367: Evans BC, Nelson CE, Yu SS, Beavers KR, Kim AJ, Li H, Nelson HM, Giorgio TD,

Duvall CL. Ex vivo red blood cell hemolysis assay for the evaluation of

pH-responsive endosomolytic agents for cytosolic delivery of biomacromolecular

drugs. J Vis Exp. 2013 Mar 9;(73):e50166. doi: 10.3791/50166. PubMed PMID:

23524982; PubMed Central PMCID: PMC3626231.

368: Zhang YJ, Gallis B, Taya M, Wang S, Ho RJ, Sasaki T. pH-responsive

artemisinin derivatives and lipid nanoparticle formulations inhibit growth of

breast cancer cells in vitro and induce down-regulation of HER family members.

PLoS One. 2013;8(3):e59086. doi: 10.1371/journal.pone.0059086. Epub 2013 Mar 14.

PubMed PMID: 23516601; PubMed Central PMCID: PMC3597601.

369: Gyarmati B, Vajna B, Némethy Á, László K, Szilágyi A. Redox- and

pH-responsive cysteamine-modified poly(aspartic acid) showing a reversible

sol-gel transition. Macromol Biosci. 2013 May;13(5):633-40. doi:

10.1002/mabi.201200420. Epub 2013 Mar 19. PubMed PMID: 23512318.

370: Colby AH, Colson YL, Grinstaff MW. Microscopy and tunable resistive pulse

sensing characterization of the swelling of pH-responsive, polymeric expansile

nanoparticles. Nanoscale. 2013 Apr 21;5(8):3496-504. doi: 10.1039/c3nr00114h.

Epub 2013 Mar 13. PubMed PMID: 23487041; PubMed Central PMCID: PMC3878811.

371: Tang DL, Song F, Chen C, Wang XL, Wang YZ. A pH-responsive

chitosan-b-poly(p-dioxanone) nanocarrier: formation and efficient antitumor drug

delivery. Nanotechnology. 2013 Apr 12;24(14):145101. doi:

10.1088/0957-4484/24/14/145101. Epub 2013 Mar 12. PubMed PMID: 23481178.

372: Chen H, Liu X, Dou Y, He B, Liu L, Wei Z, Li J, Wang C, Mao C, Zhang J, Wang

G. A pH-responsive cyclodextrin-based hybrid nanosystem as a nonviral vector for

gene delivery. Biomaterials. 2013 May;34(16):4159-72. doi:

10.1016/j.biomaterials.2013.02.035. Epub 2013 Mar 5. PubMed PMID: 23480956.

373: Tang Y, Liu L, Wu J, Duan J. Synthesis and self-assembly of

thermo/pH-responsive double hydrophilic brush-coil copolymer with poly(L-glutamic

acid) side chains. J Colloid Interface Sci. 2013 May 1;397:24-31. doi:

10.1016/j.jcis.2013.01.018. Epub 2013 Feb 8. PubMed PMID: 23452517.

374: Xiao M, Cheng M, Zhang Y, Shi F. Combining the Marangoni effect and the

pH-responsive superhydrophobicity-superhydrophilicity transition to biomimic the

locomotion process of the beetles of genus Stenus. Small. 2013 Aug

12;9(15):2509-14. doi: 10.1002/smll.201203105. Epub 2013 Mar 1. PubMed PMID:

23450523.

375: Wen S, Liu H, Cai H, Shen M, Shi X. Targeted and pH-responsive delivery of

doxorubicin to cancer cells using multifunctional dendrimer-modified multi-walled

carbon nanotubes. Adv Healthc Mater. 2013 Sep;2(9):1267-76. doi:

10.1002/adhm.201200389. Epub 2013 Feb 28. PubMed PMID: 23447549.

376: Dunderdale GJ, Fairclough JP. Coupling pH-responsive polymer brushes to

electricity: switching thickness and creating waves of swelling or collapse.

Langmuir. 2013 Mar 19;29(11):3628-35. doi: 10.1021/la3049949. Epub 2013 Mar 7.

PubMed PMID: 23441938.

377: Liu JX, Zhao MZ, Deng Y, Tie C, Chen HX, Zhou YL, Zhang XX. The coating of

smart pH-responsive polyelectrolyte brushes in capillary and its application in

CE. Electrophoresis. 2013 May;34(9-10):1352-8. doi: 10.1002/elps.201200518. Epub

2013 Apr 2. PubMed PMID: 23436557.

378: Liang W, Mason AJ, Lam JK. Western blot evaluation of siRNA delivery by

pH-responsive peptides. Methods Mol Biol. 2013;986:73-87. doi:

10.1007/978-1-62703-311-4_5. PubMed PMID: 23436406; PubMed Central PMCID:

PMC3631761.

379: Tseng SJ, Zeng YF, Deng YF, Yang PC, Liu JR, Kempson IM. Switchable delivery

of small interfering RNA using a negatively charged pH-responsive

polyethylenimine-based polyelectrolyte complex. Chem Commun (Camb). 2013 Apr

4;49(26):2670-2. doi: 10.1039/c3cc00134b. PubMed PMID: 23435386.

380: Mecca T, Messina GM, Marletta G, Cunsolo F. Novel pH responsive

calix[8]arene hydrogelators: self-organization processes at a nanometric scale.

Chem Commun (Camb). 2013 Mar 28;49(25):2530-2. doi: 10.1039/c3cc40374b. PubMed

PMID: 23423164.

381: Pawar RR, Kevadiya BD, Brahmbhatt H, Bajaj HC. Template free synthesis of

mesoporous hectorites: efficient host for pH responsive drug delivery. Int J

Pharm. 2013 Mar 25;446(1-2):145-52. doi: 10.1016/j.ijpharm.2013.02.021. Epub 2013

Feb 16. PubMed PMID: 23419664.

382: Li M, Song W, Tang Z, Lv S, Lin L, Sun H, Li Q, Yang Y, Hong H, Chen X.

Nanoscaled poly(L-glutamic acid)/doxorubicin-amphiphile complex as pH-responsive

drug delivery system for effective treatment of nonsmall cell lung cancer. ACS

Appl Mater Interfaces. 2013 Mar 13;5(5):1781-92. doi: 10.1021/am303073u. Epub

2013 Feb 27. PubMed PMID: 23410916.

383: Li L, Liu C, Zhang L, Wang T, Yu H, Wang C, Su Z. Multifunctional

magnetic-fluorescent eccentric-(concentric-Fe₃O₄@SiO₂@polyacrylic acid core-shell

nanocomposites for cell imaging and pH-responsive drug delivery. Nanoscale. 2013

Mar 21;5(6):2249-53. doi: 10.1039/c3nr33695f. PubMed PMID: 23396548.

384: Peng H, Dong R, Wang S, Zhang Z, Luo M, Bai C, Zhao Q, Li J, Chen L, Xiong

H. A pH-responsive nano-carrier with mesoporous silica nanoparticles cores and

poly(acrylic acid) shell-layers: fabrication, characterization and properties for

controlled release of salidroside. Int J Pharm. 2013 Mar 25;446(1-2):153-9. doi:

10.1016/j.ijpharm.2013.01.071. Epub 2013 Feb 7. PubMed PMID: 23395877.

385: Tarn D, Xue M, Zink JI. pH-responsive dual cargo delivery from mesoporous

silica nanoparticles with a metal-latched nanogate. Inorg Chem. 2013 Feb

18;52(4):2044-9. doi: 10.1021/ic3024265. Epub 2013 Feb 7. PubMed PMID: 23391170;

PubMed Central PMCID: PMC3800181.

386: Akita H, Ishiba R, Hatakeyama H, Tanaka H, Sato Y, Tange K, Arai M, Kubo K,

Harashima H. A neutral envelope-type nanoparticle containing pH-responsive and

SS-cleavable lipid-like material as a carrier for plasmid DNA. Adv Healthc Mater.

2013 Aug;2(8):1120-5. doi: 10.1002/adhm.201200431. Epub 2013 Feb 6. PubMed PMID:

23386367.

387: de Groot GW, Santonicola MG, Sugihara K, Zambelli T, Reimhult E, Vörös J,

Vancso GJ. Switching transport through nanopores with pH-responsive polymer

brushes for controlled ion permeability. ACS Appl Mater Interfaces. 2013

Feb;5(4):1400-7. doi: 10.1021/am302820y. Epub 2013 Feb 11. PubMed PMID: 23360664.

388: Yu H, Zou Y, Jiang L, Yin Q, He X, Chen L, Zhang Z, Gu W, Li Y. Induction of

apoptosis in non-small cell lung cancer by downregulation of MDM2 using

pH-responsive PMPC-b-PDPA/siRNA complex nanoparticles. Biomaterials. 2013

Apr;34(11):2738-47. doi: 10.1016/j.biomaterials.2012.12.042. Epub 2013 Jan 24.

PubMed PMID: 23352573.

389: Krogsgaard M, Behrens MA, Pedersen JS, Birkedal H. Self-healing

mussel-inspired multi-pH-responsive hydrogels. Biomacromolecules. 2013 Feb

11;14(2):297-301. doi: 10.1021/bm301844u. Epub 2013 Jan 28. PubMed PMID:

23347052.

390: Bauri K, Roy SG, Pant S, De P. Controlled synthesis of amino acid-based

pH-responsive chiral polymers and self-assembly of their block copolymers.

Langmuir. 2013 Feb 26;29(8):2764-74. doi: 10.1021/la304918s. Epub 2013 Feb 11.

PubMed PMID: 23346856.

391: Thomas MB, Radhakrishnan K, Gnanadhas DP, Chakravortty D, Raichur AM.

Intracellular delivery of doxorubicin encapsulated in novel pH-responsive

chitosan/heparin nanocapsules. Int J Nanomedicine. 2013;8:267-73. doi:

10.2147/IJN.S37737. Epub 2013 Jan 11. PubMed PMID: 23345974; PubMed Central

PMCID: PMC3548417.

392: Ali SA, Al Hamouz OC, Hassan NM. Novel cross-linked polymers having

pH-responsive amino acid residues for the removal of Cu2+ from aqueous solution

at low concentrations. J Hazard Mater. 2013 Mar 15;248-249:47-58. doi:

10.1016/j.jhazmat.2012.12.052. Epub 2013 Jan 4. PubMed PMID: 23337624.

393: Guillet-Nicolas R, Popat A, Bridot JL, Monteith G, Qiao SZ, Kleitz F.

pH-responsive nutraceutical-mesoporous silica nanoconjugates with enhanced

colloidal stability. Angew Chem Int Ed Engl. 2013 Feb 18;52(8):2318-22. doi:

10.1002/anie.201208840. Epub 2013 Jan 15. PubMed PMID: 23322708.

394: Chen D, Song P, Jiang F, Meng X, Sui W, Shu C, Wan LJ. pH-responsive

mechanism of a deoxycholic acid and folate comodified chitosan micelle under

cancerous environment. J Phys Chem B. 2013 Feb 7;117(5):1261-8. doi:

10.1021/jp310677p. Epub 2013 Jan 23. PubMed PMID: 23311609.

395: Chen W, Zhong P, Meng F, Cheng R, Deng C, Feijen J, Zhong Z. Redox and

pH-responsive degradable micelles for dually activated intracellular anticancer

drug release. J Control Release. 2013 Aug 10;169(3):171-9. doi:

10.1016/j.jconrel.2013.01.001. Epub 2013 Jan 8. PubMed PMID: 23306022.

396: She W, Li N, Luo K, Guo C, Wang G, Geng Y, Gu Z. Dendronized

heparin-doxorubicin conjugate based nanoparticle as pH-responsive drug delivery

system for cancer therapy. Biomaterials. 2013 Mar;34(9):2252-64. doi:

10.1016/j.biomaterials.2012.12.017. Epub 2013 Jan 5. PubMed PMID: 23298778.

397: Chapman R, Warr GG, Perrier S, Jolliffe KA. Water-soluble and pH-responsive

polymeric nanotubes from cyclic peptide templates. Chemistry. 2013 Feb

4;19(6):1955-61. doi: 10.1002/chem.201203602. Epub 2013 Jan 7. PubMed PMID:

23297172.

398: Ji X, Zhang M, Yan X, Li J, Huang F. Synthesis of a water-soluble

bis(m-phenylene)-32-crown-10-based cryptand and its pH-responsive binding to a

paraquat derivative. Chem Commun (Camb). 2013 Feb 11;49(12):1178-80. doi:

10.1039/c2cc38472h. Epub 2013 Jan 4. PubMed PMID: 23288042.

399: Schoener CA, Hutson HN, Peppas NA. pH-responsive hydrogels with dispersed

hydrophobic nanoparticles for the oral delivery of chemotherapeutics. J Biomed

Mater Res A. 2013 Aug;101(8):2229-36. doi: 10.1002/jbm.a.34532. Epub 2012 Dec 28.

PubMed PMID: 23281185; PubMed Central PMCID: PMC3619027.

400: Lee A, Lundberg P, Klinger D, Lee BF, Hawker CJ, Lynd NA. Physiologically

relevant, pH-responsive PEG-based block and statistical copolymers with

N,N-diisopropylamine units. Polym Chem. 2013;4(24):5735-5742. PubMed PMID:

25484931; PubMed Central PMCID: PMC4257845.

401: Al-Obeidi A, Ge C, Orosz KS, Saavedra SS. ITO/poly(aniline)/sol-gel glass:

An optically transparent, pH-responsive substrate for supported lipid bilayers. J

Mater. 2013;2013. pii: 676920. PubMed PMID: 25328882; PubMed Central PMCID:

PMC4201389.

402: Wang A, Gao H, Sun Y, Sun YL, Yang YW, Wu G, Wang Y, Fan Y, Ma J.

Temperature- and pH-responsive nanoparticles of biocompatible polyurethanes for

doxorubicin delivery. Int J Pharm. 2013 Jan 30;441(1-2):30-9. doi:

10.1016/j.ijpharm.2012.12.021. Epub 2012 Dec 20. PubMed PMID: 23262421.

403: Wen H, Guo J, Chang B, Yang W. pH-responsive composite microspheres based on

magnetic mesoporous silica nanoparticle for drug delivery. Eur J Pharm Biopharm.

2013 May;84(1):91-8. doi: 10.1016/j.ejpb.2012.11.019. Epub 2012 Nov 30. PubMed

PMID: 23207322.

404: Ravazzolo E, Salmaso S, Mastrotto F, Bersani S, Gallon E, Caliceti P.

pH-responsive lipid core micelles for tumour targeting. Eur J Pharm Biopharm.

2013 Apr;83(3):346-57. doi: 10.1016/j.ejpb.2012.11.002. Epub 2012 Nov 29. PubMed

PMID: 23201051.

405: Morita C, Kawai C, Kikuchi A, Imura Y, Kawai T. Effect of amide moieties for

hydrogelators on gelation property and heating-free pH responsive gel-sol phase

transition. J Oleo Sci. 2012;61(12):707-13. PubMed PMID: 23196871.

406: She W, Luo K, Zhang C, Wang G, Geng Y, Li L, He B, Gu Z. The potential of

self-assembled, pH-responsive nanoparticles of mPEGylated peptide

dendron-doxorubicin conjugates for cancer therapy. Biomaterials. 2013

Feb;34(5):1613-23. doi: 10.1016/j.biomaterials.2012.11.007. Epub 2012 Nov 26.

PubMed PMID: 23195490.

407: Wu J, Jia W, Lu W, Jiang L. Shape homogenization and long-range arrangement

of gold nanorods using a pH-responsive multiamine surfactant. ACS Appl Mater

Interfaces. 2012 Dec;4(12):6560-4. doi: 10.1021/am302507u. Epub 2012 Dec 7.

PubMed PMID: 23186139.

408: Song L, Ho VH, Chen C, Yang Z, Liu D, Chen R, Zhou D. Efficient,

pH-triggered drug delivery using a pH-responsive DNA-conjugated gold

nanoparticle. Adv Healthc Mater. 2013 Feb;2(2):275-80. doi:

10.1002/adhm.201200112. Epub 2012 Oct 4. PubMed PMID: 23184521.

409: Xue M, Findenegg GH. Lysozyme as a pH-responsive valve for the controlled

release of guest molecules from mesoporous silica. Langmuir. 2012 Dec

18;28(50):17578-84. doi: 10.1021/la304152j. Epub 2012 Dec 5. PubMed PMID:

23173551.

410: Tseng WC, Su LY, Fang TY. pH responsive PEGylation through metal affinity

for gene delivery mediated by histidine-grafted polyethylenimine. J Biomed Mater

Res B Appl Biomater. 2013 Feb;101(2):375-86. doi: 10.1002/jbm.b.32848. Epub 2012

Nov 19. PubMed PMID: 23165821.

411: Chen T, Fu J. An intelligent anticorrosion coating based on pH-responsive

supramolecular nanocontainers. Nanotechnology. 2012 Dec 21;23(50):505705. doi:

10.1088/0957-4484/23/50/505705. Epub 2012 Nov 19. PubMed PMID: 23165151.

412: Liu J, Guo S, Han L, Ren W, Liu Y, Wang E. Multiple pH-responsive graphene

composites by non-covalent modification with chitosan. Talanta. 2012 Nov

15;101:151-6. doi: 10.1016/j.talanta.2012.09.013. Epub 2012 Sep 18. PubMed PMID:

23158305.

413: Liang YH, Liu CH, Liao SH, Lin YY, Tang HW, Liu SY, Lai IR, Wu KC.

Cosynthesis of cargo-loaded hydroxyapatite/alginate core-shell nanoparticles

(HAP@Alg) as pH-responsive nanovehicles by a pre-gel method. ACS Appl Mater

Interfaces. 2012 Dec;4(12):6720-7. doi: 10.1021/am301895u. Epub 2012 Dec 10.

PubMed PMID: 23151216.

414: Chen Z, Li Z, Lin Y, Yin M, Ren J, Qu X. Biomineralization inspired surface

engineering of nanocarriers for pH-responsive, targeted drug delivery.

Biomaterials. 2013 Jan;34(4):1364-71. doi: 10.1016/j.biomaterials.2012.10.060.

Epub 2012 Nov 9. PubMed PMID: 23140999.

415: Chen YH, Chang SH, Wang TJ, Wang IJ, Young TH. Cell fractionation on

pH-responsive chitosan surface. Biomaterials. 2013 Jan;34(4):854-63. doi:

10.1016/j.biomaterials.2012.10.014. Epub 2012 Nov 9. PubMed PMID: 23140996.

416: Nam J, Nam H, Jung S, Hwang S, Wang T, Hur J, Im K, Park N, Kim KH, Kim S.

Unique photothermal response and sustained photothermal effect of pH-responsive

gold-nanoparticle aggregates. Chemphyschem. 2012 Dec 21;13(18):4105-9. doi:

10.1002/cphc.201200720. Epub 2012 Nov 6. PubMed PMID: 23132778.

417: Bian Q, Xiao Y, Zhou C, Lang M. Synthesis, self-assembly, and pH-responsive

behavior of (photo-crosslinked) star amphiphilic triblock copolymer. J Colloid

Interface Sci. 2013 Feb 15;392:141-50. doi: 10.1016/j.jcis.2012.08.076. Epub 2012

Oct 16. PubMed PMID: 23127872.

418: Krannig KS, Schlaad H. pH-responsive bioactive glycopolypeptides with

enhanced helicity and solubility in aqueous solution. J Am Chem Soc. 2012 Nov

14;134(45):18542-5. doi: 10.1021/ja308772d. Epub 2012 Oct 31. PubMed PMID:

23102491.

419: Daniels CR, Tauzin LJ, Foster E, Advincula RC, Landes CF. On the

pH-responsive, charge-selective, polymer-brush-mediated transport probed by

traditional and scanning fluorescence correlation spectroscopy. J Phys Chem B.

2013 Apr 25;117(16):4284-90. doi: 10.1021/jp3053828. Epub 2012 Nov 9. PubMed

PMID: 23092304; PubMed Central PMCID: PMC3671586.

420: Schoener CA, Hutson HN, Peppas NA. pH-Responsive Hydrogels with Dispersed

Hydrophobic Nanoparticles for the Delivery of Hydrophobic Therapeutic Agents.

Polym Int. 2012 Jun 1;61(6):874-879. Epub 2012 Apr 11. PubMed PMID: 23087546;

PubMed Central PMCID: PMC3474376.

421: Longo DL, Busato A, Lanzardo S, Antico F, Aime S. Imaging the pH evolution

of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive

contrast agent. Magn Reson Med. 2013 Sep;70(3):859-64. doi: 10.1002/mrm.24513.

Epub 2012 Oct 11. PubMed PMID: 23059893.

422: Ke CJ, Chiang WL, Liao ZX, Chen HL, Lai PS, Sun JS, Sung HW. Real-time

visualization of pH-responsive PLGA hollow particles containing a gas-generating

agent targeted for acidic organelles for overcoming multi-drug resistance.

Biomaterials. 2013 Jan;34(1):1-10. doi: 10.1016/j.biomaterials.2012.09.023. Epub

2012 Oct 6. PubMed PMID: 23044041.

423: Zhou T, Chen P, Niu L, Jin J, Liang D, Li Z, Yang Z, Liu D. pH-responsive

size-tunable self-assembled DNA dendrimers. Angew Chem Int Ed Engl. 2012 Nov

5;51(45):11271-4. doi: 10.1002/anie.201205862. Epub 2012 Oct 4. PubMed PMID:

23037637.

424: Jiang T, Zhang Z, Zhang Y, Lv H, Zhou J, Li C, Hou L, Zhang Q.

Dual-functional liposomes based on pH-responsive cell-penetrating peptide and

hyaluronic acid for tumor-targeted anticancer drug delivery. Biomaterials. 2012

Dec;33(36):9246-58. doi: 10.1016/j.biomaterials.2012.09.027. Epub 2012 Sep 29.

PubMed PMID: 23031530.

425: Li WM, Chen SY, Liu DM. In situ doxorubicin-CaP shell formation on

amphiphilic gelatin-iron oxide core as a multifunctional drug delivery system

with improved cytocompatibility, pH-responsive drug release and MR imaging. Acta

Biomater. 2013 Feb;9(2):5360-8. doi: 10.1016/j.actbio.2012.09.023. Epub 2012 Sep

26. PubMed PMID: 23022876.

426: Dadsetan M, Taylor KE, Yong C, Bajzer Z, Lu L, Yaszemski MJ. Controlled

release of doxorubicin from pH-responsive microgels. Acta Biomater. 2013

Mar;9(3):5438-46. doi: 10.1016/j.actbio.2012.09.019. Epub 2012 Sep 25. PubMed

PMID: 23022545; PubMed Central PMCID: PMC3970914.

427: Gummadi L, Taylor L, Curthoys NP. Concurrent binding and modifications of

AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate

carboxykinase mRNA in kidney cells. Am J Physiol Renal Physiol. 2012 Dec

1;303(11):F1545-54. doi: 10.1152/ajprenal.00400.2012. Epub 2012 Sep 26. PubMed

PMID: 23019227; PubMed Central PMCID: PMC3532484.

428: Shalviri A, Chan HK, Raval G, Abdekhodaie MJ, Liu Q, Heerklotz H, Wu XY.

Design of pH-responsive nanoparticles of terpolymer of poly(methacrylic acid),

polysorbate 80 and starch for delivery of doxorubicin. Colloids Surf B

Biointerfaces. 2013 Jan 1;101:405-13. doi: 10.1016/j.colsurfb.2012.07.015. Epub

2012 Jul 20. PubMed PMID: 23010048.

429: Luo GF, Xu XD, Zhang J, Yang J, Gong YH, Lei Q, Jia HZ, Li C, Zhuo RX, Zhang

XZ. Encapsulation of an adamantane-doxorubicin prodrug in pH-responsive

polysaccharide capsules for controlled release. ACS Appl Mater Interfaces. 2012

Oct 24;4(10):5317-24. doi: 10.1021/am301258a. Epub 2012 Oct 5. PubMed PMID:

23009157.

430: Xing L, Zheng H, Cao Y, Che S. Coordination polymer coated mesoporous silica

nanoparticles for pH-responsive drug release. Adv Mater. 2012 Dec

18;24(48):6433-7. doi: 10.1002/adma.201201742. Epub 2012 Sep 24. PubMed PMID:

23001882.

431: Du L, Jin Y, Yang J, Wang S, Wang X. A functionalized poly(amidoamine)

nanocarrier-loading 5-fluorouracil: pH-responsive drug release and enhanced

anticancer effect. Anticancer Drugs. 2013 Feb;24(2):172-80. doi:

10.1097/CAD.0b013e32835920fa. PubMed PMID: 22990130.

432: Li L, He F, Wang X, Ma N, Li L. Reversible pH-responsive fluorescence of

water-soluble polyfluorenes and their application in metal ion detection. ACS

Appl Mater Interfaces. 2012 Sep 26;4(9):4927-33. Epub 2012 Sep 17. PubMed PMID:

22956652.

433: Truman LK, Comby S, Gunnlaugsson T. pH-responsive luminescent

lanthanide-functionalized gold nanoparticles with "on-off" ytterbium switchable

near-infrared emission. Angew Chem Int Ed Engl. 2012 Sep 17;51(38):9624-7. doi:

10.1002/anie.201200887. Epub 2012 Aug 29. PubMed PMID: 22930485.

434: Brickman TJ, Armstrong SK. Iron and pH-responsive FtrABCD ferrous iron

utilization system of Bordetella species. Mol Microbiol. 2012 Nov;86(3):580-93.

doi: 10.1111/mmi.12003. Epub 2012 Sep 11. PubMed PMID: 22924881; PubMed Central

PMCID: PMC3805130.

435: Ke MR, Ng DK, Lo PC. A pH-responsive fluorescent probe and photosensitiser

based on a self-quenched phthalocyanine dimer. Chem Commun (Camb). 2012 Sep

18;48(72):9065-7. doi: 10.1039/c2cc34327d. Epub 2012 Aug 3. PubMed PMID:

22864462.

436: Bai Y, Zhang Z, Zhang A, Chen L, He C, Zhuang X, Chen X. Novel thermo- and

pH-responsive hydroxypropyl cellulose- and poly (L-glutamic acid)-based microgels

for oral insulin controlled release. Carbohydr Polym. 2012 Aug 1;89(4):1207-14.

doi: 10.1016/j.carbpol.2012.03.095. Epub 2012 Apr 6. PubMed PMID: 24750933.

437: Smith DG, McMahon BK, Pal R, Parker D. Live cell imaging of lysosomal pH

changes with pH responsive ratiometric lanthanide probes. Chem Commun (Camb).

2012 Sep 4;48(68):8520-2. doi: 10.1039/c2cc34267g. Epub 2012 Jul 23. PubMed PMID:

22820610.

438: Morse AJ, Dupin D, Thompson KL, Armes SP, Ouzineb K, Mills P, Swart R. Novel

Pickering emulsifiers based on pH-responsive poly(tert-butylaminoethyl

methacrylate) latexes. Langmuir. 2012 Aug 14;28(32):11733-44. doi:

10.1021/la301936k. Epub 2012 Aug 1. PubMed PMID: 22794126.

439: Barea MJ, Jenkins MJ, Lee YS, Johnson P, Bridson RH. Encapsulation of

Liposomes within pH Responsive Microspheres for Oral Colonic Drug Delivery. Int J

Biomater. 2012;2012:458712. doi: 10.1155/2012/458712. Epub 2012 Jun 27. PubMed

PMID: 22792110; PubMed Central PMCID: PMC3391899.

440: Chen Y, Yin Q, Ji X, Zhang S, Chen H, Zheng Y, Sun Y, Qu H, Wang Z, Li Y,

Wang X, Zhang K, Zhang L, Shi J. Manganese oxide-based multifunctionalized

mesoporous silica nanoparticles for pH-responsive MRI, ultrasonography and

circumvention of MDR in cancer cells. Biomaterials. 2012 Oct;33(29):7126-37. doi:

10.1016/j.biomaterials.2012.06.059. Epub 2012 Jul 11. PubMed PMID: 22789722.

441: Muser SE, Paukstelis PJ. Three-dimensional DNA crystals with pH-responsive

noncanonical junctions. J Am Chem Soc. 2012 Aug 1;134(30):12557-64. doi:

10.1021/ja3025033. Epub 2012 Jul 18. PubMed PMID: 22768973.

442: Huang X, Jiang X, Zhuo R. Microwave-assisted solid-phase synthesis of

pH-responsive polyaspartamide derivatives. Carbohydr Polym. 2012 Jul

1;89(3):788-94. doi: 10.1016/j.carbpol.2012.04.012. Epub 2012 Apr 13. PubMed

PMID: 24750863.

443: Shin JY, Yang Y, Heo P, Lee JC, Kong B, Cho JY, Yoon K, Shin CS, Seo JH, Kim

SG, Kweon DH. pH-responsive high-density lipoprotein-like nanoparticles to

release paclitaxel at acidic pH in cancer chemotherapy. Int J Nanomedicine.

2012;7:2805-16. doi: 10.2147/IJN.S29817. Epub 2012 Jun 6. PubMed PMID: 22745543;

PubMed Central PMCID: PMC3383266.

444: Shi P, Qu K, Wang J, Li M, Ren J, Qu X. pH-responsive NIR enhanced drug

release from gold nanocages possesses high potency against cancer cells. Chem

Commun (Camb). 2012 Aug 7;48(61):7640-2. doi: 10.1039/c2cc33543c. Epub 2012 Jun

27. PubMed PMID: 22735385.

445: Ban T, Yamagami T, Furumichi Y. Transient pore dynamics in pH-responsive

liquid membrane. Langmuir. 2012 Jul 24;28(29):10682-7. doi: 10.1021/la301481p.

Epub 2012 Jul 10. PubMed PMID: 22726226.

446: Gianolio E, Porto S, Napolitano R, Baroni S, Giovenzana GB, Aime S.

Relaxometric investigations and MRI evaluation of a liposome-loaded pH-responsive

gadolinium(III) complex. Inorg Chem. 2012 Jul 2;51(13):7210-7. doi:

10.1021/ic300447n. Epub 2012 Jun 20. PubMed PMID: 22716284.

447: Li C, Mezzenga R. Functionalization of multiwalled carbon nanotubes and

their pH-responsive hydrogels with amyloid fibrils. Langmuir. 2012 Jul

10;28(27):10142-6. doi: 10.1021/la301541d. Epub 2012 Jun 25. PubMed PMID:

22712696.

448: Zhang CY, Yang YQ, Huang TX, Zhao B, Guo XD, Wang JF, Zhang LJ.

Self-assembled pH-responsive MPEG-b-(PLA-co-PAE) block copolymer micelles for

anticancer drug delivery. Biomaterials. 2012 Sep;33(26):6273-83. doi:

10.1016/j.biomaterials.2012.05.025. Epub 2012 Jun 12. PubMed PMID: 22695069.

449: Li S, Meng F, Wang Z, Zhong Y, Zheng M, Liu H, Zhong Z. Biodegradable

polymersomes with an ionizable membrane: facile preparation, superior protein

loading, and endosomal pH-responsive protein release. Eur J Pharm Biopharm. 2012

Sep;82(1):103-11. doi: 10.1016/j.ejpb.2012.05.009. Epub 2012 Jun 9. PubMed PMID:

22691417.

450: Mo R, Sun Q, Xue J, Li N, Li W, Zhang C, Ping Q. Multistage pH-responsive

liposomes for mitochondrial-targeted anticancer drug delivery. Adv Mater. 2012

Jul 17;24(27):3659-65. doi: 10.1002/adma.201201498. Epub 2012 Jun 8. PubMed PMID:

22678851.

451: Dalmolin RJ, Gelain DP, Klamt F, Castro MA, Moreira JC. Transcriptomic

analysis reveals pH-responsive antioxidant gene networks. Front Biosci (Schol

Ed). 2012 Jun 1;4:1556-67. Review. PubMed PMID: 22652892.

452: Bonde JS, Bülow L. Use of human amelogenin in molecular encapsulation for

the design of pH responsive microparticles. BMC Biotechnol. 2012 May 25;12:25.

doi: 10.1186/1472-6750-12-25. PubMed PMID: 22630169; PubMed Central PMCID:

PMC3403901.

453: Chen T, Fu J. pH-responsive nanovalves based on hollow mesoporous silica

spheres for controlled release of corrosion inhibitor. Nanotechnology. 2012 Jun

15;23(23):235605. doi: 10.1088/0957-4484/23/23/235605. Epub 2012 May 17. PubMed

PMID: 22595678.

454: Lin BF, Missirlis D, Krogstad DV, Tirrell M. Structural effects and lipid

membrane interactions of the pH-responsive GALA peptide with fatty acid

acylation. Biochemistry. 2012 Jun 12;51(23):4658-68. doi: 10.1021/bi300314h. Epub

2012 May 31. PubMed PMID: 22591394.

455: Xing L, Cao Y, Che S. Synthesis of core-shell coordination polymer

nanoparticles (CPNs) for pH-responsive controlled drug release. Chem Commun

(Camb). 2012 May 10. [Epub ahead of print] PubMed PMID: 22576702.

456: Kamimura M, Kim JO, Kabanov AV, Bronich TK, Nagasaki Y. Block ionomer

complexes of PEG-block-poly(4-vinylbenzylphosphonate) and cationic surfactants as

highly stable, pH responsive drug delivery system. J Control Release. 2012 Jun

28;160(3):486-94. doi: 10.1016/j.jconrel.2012.04.027. Epub 2012 Apr 23. PubMed

PMID: 22546682.

457: Xu GK, Feng XQ, Li B, Gao H. Controlled release and assembly of drug

nanoparticles via pH-responsive polymeric micelles: a theoretical study. J Phys

Chem B. 2012 May 24;116(20):6003-9. doi: 10.1021/jp3007816. Epub 2012 May 10.

PubMed PMID: 22546144.

458: Walsh CL, Nguyen J, Szoka FC. Synthesis and characterization of novel

zwitterionic lipids with pH-responsive biophysical properties. Chem Commun

(Camb). 2012 Jun 7;48(45):5575-7. doi: 10.1039/c2cc31710a. Epub 2012 Apr 26.

PubMed PMID: 22538384.

459: Wang X, Wu G, Lu C, Zhao W, Wang Y, Fan Y, Gao H, Ma J. A novel delivery

system of doxorubicin with high load and pH-responsive release from the

nanoparticles of poly (α,β-aspartic acid) derivative. Eur J Pharm Sci. 2012 Aug

30;47(1):256-64. doi: 10.1016/j.ejps.2012.04.007. Epub 2012 Apr 13. PubMed PMID:

22522116.

460: Jiang Z, Li X, Yang G, Cheng L, Cai B, Yang Y, Dong J. pH-responsive surface

activity and solubilization with novel pyrrolidone-based Gemini surfactants.

Langmuir. 2012 May 8;28(18):7174-81. doi: 10.1021/la3008156. Epub 2012 Apr 23.

PubMed PMID: 22502732.

461: Palpant NJ, Houang EM, Sham YY, Metzger JM. pH-responsive titratable

inotropic performance of histidine-modified cardiac troponin I. Biophys J. 2012

Apr 4;102(7):1570-9. doi: 10.1016/j.bpj.2012.01.024. Epub 2012 Apr 3. PubMed

PMID: 22500757; PubMed Central PMCID: PMC3318134.

462: Ji X, Zhu K, Yan X, Ma Y, Li J, Hu B, Yu Y, Huang F. pH-responsive

supramolecular polymerization in aqueous media driven by electrostatic

attraction-enhanced crown ether-based molecular recognition. Macromol Rapid

Commun. 2012 Jul 26;33(14):1197-202. doi: 10.1002/marc.201200117. Epub 2012 Apr

12. PubMed PMID: 22495805.

463: Qiu L, Zheng C, Zhao Q. Mechanisms of drug resistance reversal in

Dox-resistant MCF-7 cells by pH-responsive amphiphilic polyphosphazene containing

diisopropylamino side groups. Mol Pharm. 2012 May 7;9(5):1109-17. doi:

10.1021/mp200356w. Epub 2012 Apr 25. PubMed PMID: 22494535.

464: Drachuk I, Shchepelina O, Lisunova M, Harbaugh S, Kelley-Loughnane N, Stone

M, Tsukruk VV. pH-responsive layer-by-layer nanoshells for direct regulation of

cell activity. ACS Nano. 2012 May 22;6(5):4266-78. doi: 10.1021/nn3008355. Epub

2012 Apr 17. PubMed PMID: 22489604.

465: Ke CJ, Lin YJ, Hu YC, Chiang WL, Chen KJ, Yang WC, Liu HL, Fu CC, Sung HW.

Multidrug release based on microneedle arrays filled with pH-responsive PLGA

hollow microspheres. Biomaterials. 2012 Jul;33(20):5156-65. doi:

10.1016/j.biomaterials.2012.03.056. Epub 2012 Apr 7. PubMed PMID: 22484044.

466: Shishmanova IK, Bastiaansen CW, Schenning AP, Broer DJ. Two-dimensional

pH-responsive printable smectic hydrogels. Chem Commun (Camb). 2012 May

14;48(38):4555-7. doi: 10.1039/c2cc16873a. Epub 2012 Mar 30. PubMed PMID:

22468264.

467: Jiang T, Zukoski CF. Synthesis of pH-responsive particles with shape

anisotropy. Langmuir. 2012 May 1;28(17):6760-8. doi: 10.1021/la300376r. Epub 2012

Apr 18. PubMed PMID: 22462482.

468: Saito Y, Miyamoto S, Suzuki A, Matsumoto K, Ishihara T, Saito I. Fluorescent

nucleosides with 'on-off' switching function, pH-responsive fluorescent uridine

derivatives. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2753-6. doi:

10.1016/j.bmcl.2012.02.092. Epub 2012 Mar 3. PubMed PMID: 22444678.

469: Uesaka A, Ueda M, Makino A, Imai T, Sugiyama J, Kimura S. Self-assemblies of

triskelion A2B-type amphiphilic polypeptide showing pH-responsive morphology

transformation. Langmuir. 2012 Apr 10;28(14):6006-12. doi: 10.1021/la3004867.

Epub 2012 Mar 30. PubMed PMID: 22440231.

470: Yan Y, Li J, Zheng J, Pan Y, Wang J, He X, Zhang L, Liu D.

Poly(L-lysine)-based star-block copolymers as pH-responsive nanocarriers for

anionic drugs. Colloids Surf B Biointerfaces. 2012 Jun 15;95:137-43. doi:

10.1016/j.colsurfb.2012.02.034. Epub 2012 Mar 3. PubMed PMID: 22424829.

471: Chen JK, Pai PC, Chang JY, Fan SK. pH-responsive one-dimensional periodic

relief grating of polymer brush-gold nanoassemblies on silicon surface. ACS Appl

Mater Interfaces. 2012 Apr;4(4):1935-47. doi: 10.1021/am201632e. Epub 2012 Mar

27. PubMed PMID: 22423620.

472: Lee S, Saito K, Lee HR, Lee MJ, Shibasaki Y, Oishi Y, Kim BS. Hyperbranched

double hydrophilic block copolymer micelles of poly(ethylene oxide) and

polyglycerol for pH-responsive drug delivery. Biomacromolecules. 2012 Apr

9;13(4):1190-6. doi: 10.1021/bm300151m. Epub 2012 Mar 27. PubMed PMID: 22414172.

473: Khoee S, Rahmatolahzadeh R. Synthesis and characterization of pH-responsive

and folated nanoparticles based on self-assembled brush-like PLGA/PEG/AEMA

copolymer with targeted cancer therapy properties: A comprehensive kinetic study.

Eur J Med Chem. 2012 Apr;50:416-27. doi: 10.1016/j.ejmech.2012.02.027. Epub 2012

Feb 22. PubMed PMID: 22397922.

474: Zheng H, Huang Z, Che S. Mesostructured chitosan-silica hybrid as a

biodegradable carrier for a pH-responsive drug delivery system. Dalton Trans.

2012 Apr 28;41(16):5038-44. doi: 10.1039/c2dt12347a. Epub 2012 Mar 1. PubMed

PMID: 22378252.

475: Yan Y, Wei D, Li J, Zheng J, Shi G, Luo W, Pan Y, Wang J, Zhang L, He X, Liu

D. A poly(L-lysine)-based hydrophilic star block co-polymer as a protein

nanocarrier with facile encapsulation and pH-responsive release. Acta Biomater.

2012 Jul;8(6):2113-20. doi: 10.1016/j.actbio.2012.02.016. Epub 2012 Feb 25.

PubMed PMID: 22373818.

476: Li C, Xing L, Che S. Coordination bonding based pH-responsive albumin

nanoparticles for anticancer drug delivery. Dalton Trans. 2012 Apr

7;41(13):3714-9. doi: 10.1039/c2dt30226h. Epub 2012 Feb 27. PubMed PMID:

22370556.

477: Kim JH, Li Y, Kim MS, Kang SW, Jeong JH, Lee DS. Synthesis and evaluation of

biotin-conjugated pH-responsive polymeric micelles as drug carriers. Int J Pharm.

2012 May 10;427(2):435-42. doi: 10.1016/j.ijpharm.2012.01.034. Epub 2012 Feb 7.

PubMed PMID: 22342467.

478: Manchun S, Dass CR, Sriamornsak P. Targeted therapy for cancer using

pH-responsive nanocarrier systems. Life Sci. 2012 Mar 10;90(11-12):381-7. doi:

10.1016/j.lfs.2012.01.008. Epub 2012 Feb 1. Review. PubMed PMID: 22326503.

479: Zhang H, Wang C, Chen B, Wang X. Daunorubicin-TiO2 nanocomposites as a

"smart" pH-responsive drug delivery system. Int J Nanomedicine. 2012;7:235-42.

doi: 10.2147/IJN.S27722. Epub 2012 Jan 12. PubMed PMID: 22275838; PubMed Central

PMCID: PMC3263415.

480: Fares MM, Al-Shboul AM. Stimuli pH-responsive (N-vinyl

imidazole-co-acryloylmorpholine) hydrogels; mesoporous and nanoporous scaffolds.

J Biomed Mater Res A. 2012 Apr;100(4):863-71. doi: 10.1002/jbm.a.33304. Epub 2012

Jan 24. PubMed PMID: 22275305.

481: Wang HF, Jia HZ, Cheng SX, Feng J, Zhang XZ, Zhuo RX. PEG-stabilized

micellar system with positively charged polyester core for fast pH-responsive

drug release. Pharm Res. 2012 Jun;29(6):1582-94. doi: 10.1007/s11095-012-0669-9.

Epub 2012 Jan 21. PubMed PMID: 22271048.

482: Snead CM, Smith SM, Sadeghein N, Lacruz RS, Hu P, Kurtz I, Paine ML.

Identification of a pH-responsive DNA region upstream of the transcription start

site of human NBCe1-B. Eur J Oral Sci. 2011 Dec;119 Suppl 1:136-41. doi:

10.1111/j.1600-0722.2011.00867.x. PubMed PMID: 22243239; PubMed Central PMCID:

PMC3374727.

483: Curcio A, Marotta R, Riedinger A, Palumberi D, Falqui A, Pellegrino T.

Magnetic pH-responsive nanogels as multifunctional delivery tools for small

interfering RNA (siRNA) molecules and iron oxide nanoparticles (IONPs). Chem

Commun (Camb). 2012 Feb 28;48(18):2400-2. doi: 10.1039/c2cc17223b. Epub 2012 Jan

23. PubMed PMID: 22266784.

484: Sung HW, Sonaje K, Liao ZX, Hsu LW, Chuang EY. pH-responsive nanoparticles

shelled with chitosan for oral delivery of insulin: from mechanism to therapeutic

applications. Acc Chem Res. 2012 Apr 17;45(4):619-29. doi: 10.1021/ar200234q.

Epub 2012 Jan 11. Review. PubMed PMID: 22236133.

485: Iacobucci V, Di Giuseppe F, Bui TT, Vermeer LS, Patel J, Scherman D, Kichler

A, Drake AF, Mason AJ. Control of pH responsive peptide self-association during

endocytosis is required for effective gene transfer. Biochim Biophys Acta. 2012

May;1818(5):1332-41. doi: 10.1016/j.bbamem.2011.12.018. Epub 2011 Dec 29. PubMed

PMID: 22226847; PubMed Central PMCID: PMC3378503.

486: Okada S, Mizukami S, Kikuchi K. Switchable MRI contrast agents based on

morphological changes of pH-responsive polymers. Bioorg Med Chem. 2012 Jan

15;20(2):769-74. doi: 10.1016/j.bmc.2011.12.005. Epub 2011 Dec 8. PubMed PMID:

22206870.

487: Zhao BX, Zhao Y, Huang Y, Luo LM, Song P, Wang X, Chen S, Yu KF, Zhang X,

Zhang Q. The efficiency of tumor-specific pH-responsive peptide-modified

polymeric micelles containing paclitaxel. Biomaterials. 2012 Mar;33(8):2508-20.

doi: 10.1016/j.biomaterials.2011.11.078. Epub 2011 Dec 23. PubMed PMID: 22197569.

488: Dai Y, Zhang C, Cheng Z, Ma P, Li C, Kang X, Yang D, Lin J. pH-responsive

drug delivery system based on luminescent CaF(2):Ce(3+)/Tb(3+)-poly(acrylic acid)

hybrid microspheres. Biomaterials. 2012 Mar;33(8):2583-92. doi:

10.1016/j.biomaterials.2011.12.014. Epub 2011 Dec 21. PubMed PMID: 22196902.

489: Chen W, Meng F, Cheng R, Zhong Z. Rapidly pH-responsive degradable

polymersomes for triggered release of hydrophilic and hydrophobic anticancer

drugs. J Control Release. 2011 Nov 30;152 Suppl 1:e7-9. doi:

10.1016/j.jconrel.2011.08.088. PubMed PMID: 22195934.

490: Chen D, Li N, Xia X, Xu Q, Ge J, Li Y, Lu J, Gu H. pH-responsive

polymeric-cargo encapsulated magnetic nanoparticles for selective release and

imaging. J Control Release. 2011 Nov 30;152 Suppl 1:e67-8. doi:

10.1016/j.jconrel.2011.08.127. PubMed PMID: 22195932.

491: Yan Y, Liao L, Liu D. Poly(L-glutamic acid)-based star-block copolymers as

pH-responsive release systems. J Control Release. 2011 Nov 30;152 Suppl 1:e60-1.

doi: 10.1016/j.jconrel.2011.08.122. PubMed PMID: 22195927.

492: He J, Shao H, Zhang M, Ni P. Novel pH-responsive polyphosphoester-based

hydrogels with fast gelation. J Control Release. 2011 Nov 30;152 Suppl 1:e232-3.

doi: 10.1016/j.jconrel.2011.09.030. PubMed PMID: 22195877.

493: Boylan NJ, Kim AJ, Suk JS, Adstamongkonkul P, Simons BW, Lai SK, Cooper MJ,

Hanes J. Enhancement of airway gene transfer by DNA nanoparticles using a

pH-responsive block copolymer of polyethylene glycol and poly-L-lysine.

Biomaterials. 2012 Mar;33(7):2361-71. doi: 10.1016/j.biomaterials.2011.11.080.

Epub 2011 Dec 17. PubMed PMID: 22182747; PubMed Central PMCID: PMC3259202.

494: Ouadahi K, Sbargoud K, Allard E, Larpent C. FRET-mediated pH-responsive dual

fluorescent nanoparticles prepared via click chemistry. Nanoscale. 2012 Feb

7;4(3):727-32. doi: 10.1039/c2nr11413e. Epub 2011 Dec 16. PubMed PMID: 22179667.

495: El Malah T, Ciesielski A, Piot L, Troyanov SI, Mueller U, Weidner S, Samorì

P, Hecht S. Conformationally pre-organized and pH-responsive flat dendrons:

synthesis and self-assembly at the liquid-solid interface. Nanoscale. 2012 Jan

21;4(2):467-72. doi: 10.1039/c1nr11434d. Epub 2011 Dec 2. PubMed PMID: 22139437.

496: Lam JK, Liang W, Lan Y, Chaudhuri P, Chow MY, Witt K, Kudsiova L, Mason AJ.

Effective endogenous gene silencing mediated by pH responsive peptides proceeds

via multiple pathways. J Control Release. 2012 Mar 10;158(2):293-303. doi:

10.1016/j.jconrel.2011.11.024. Epub 2011 Nov 26. PubMed PMID: 22138072; PubMed

Central PMCID: PMC3309421.

497: Nogueira DR, Mitjans M, Morán MC, Pérez L, Vinardell MP.

Membrane-destabilizing activity of pH-responsive cationic lysine-based

surfactants: role of charge position and alkyl chain length. Amino Acids. 2012

Sep;43(3):1203-15. doi: 10.1007/s00726-011-1176-8. Epub 2011 Dec 2. PubMed PMID:

22134583.

498: Banerjee I, Mishra D, Das T, Maiti TK. Wound pH-responsive sustained release

of therapeutics from a poly(NIPAAm-co-AAc) hydrogel. J Biomater Sci Polym Ed.

2012;23(1-4):111-32. doi: 10.1163/092050610X545049. PubMed PMID: 22133349.

499: Gu YJ, Cheng J, Jin J, Cheng SH, Wong WT. Development and evaluation of

pH-responsive single-walled carbon nanotube-doxorubicin complexes in cancer

cells. Int J Nanomedicine. 2011;6:2889-98. doi: 10.2147/IJN.S25162. Epub 2011 Nov

17. PubMed PMID: 22131835; PubMed Central PMCID: PMC3224716.

500: Amali AJ, Singh S, Rangaraj N, Patra D, Rana RK. Poly(L-Lysine)-pyranine-3

coacervate mediated nanoparticle-assembly: fabrication of dynamic pH-responsive

containers. Chem Commun (Camb). 2012 Jan 21;48(6):856-8. doi: 10.1039/c1cc15209b.

Epub 2011 Nov 28. PubMed PMID: 22124198.

501: Rao N V, Mane SR, Kishore A, Das Sarma J, Shunmugam R. Norbornene derived

doxorubicin copolymers as drug carriers with pH responsive hydrazone linker.

Biomacromolecules. 2012 Jan 9;13(1):221-30. doi: 10.1021/bm201478k. Epub 2011 Dec

6. PubMed PMID: 22107051.

502: Dan K, Ghosh S. pH-Responsive Aggregation of Amphiphilic Glyco-Homopolymer.

Macromol Rapid Commun. 2012 Jan;33(2):127-32. doi: 10.1002/marc.201100645. Epub

2011 Nov 16. PubMed PMID: 22086837.

503: Chen YH, Chung YC, Wang IJ, Young TH. Control of cell attachment on

pH-responsive chitosan surface by precise adjustment of medium pH. Biomaterials.

2012 Feb;33(5):1336-42. doi: 10.1016/j.biomaterials.2011.10.048. Epub 2011 Nov

10. PubMed PMID: 22078808.

504: Duan C, Gao J, Zhang D, Jia L, Liu Y, Zheng D, Liu G, Tian X, Wang F, Zhang

Q. Galactose-decorated pH-responsive nanogels for hepatoma-targeted delivery of

oridonin. Biomacromolecules. 2011 Dec 12;12(12):4335-43. doi: 10.1021/bm201270m.

Epub 2011 Nov 16. PubMed PMID: 22077387.

505: Huang WC, Chiang WH, Huang YF, Lin SC, Shih ZF, Chern CS, Chiang CS, Chiu

HC. Nano-scaled pH-responsive polymeric vesicles for intracellular release of

doxorubicin. J Drug Target. 2011 Dec;19(10):944-53. doi:

10.3109/1061186X.2011.632012. Epub 2011 Nov 3. PubMed PMID: 22050402.

506: Kulkarni RV, Boppana R, Krishna Mohan G, Mutalik S, Kalyane NV.

pH-responsive interpenetrating network hydrogel beads of

poly(acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug

delivery: synthesis, in vitro and in vivo evaluation. J Colloid Interface Sci.

2012 Feb 1;367(1):509-17. doi: 10.1016/j.jcis.2011.10.025. Epub 2011 Oct 19.

PubMed PMID: 22047923.

507: Yu H, Zou Y, Wang Y, Huang X, Huang G, Sumer BD, Boothman DA, Gao J.

Overcoming endosomal barrier by amphotericin B-loaded dual pH-responsive

PDMA-b-PDPA micelleplexes for siRNA delivery. ACS Nano. 2011 Nov

22;5(11):9246-55. doi: 10.1021/nn203503h. Epub 2011 Nov 1. PubMed PMID: 22011045.

508: Hu H, Yu J, Li Y, Zhao J, Dong H. Engineering of a novel pluronic

F127/graphene nanohybrid for pH responsive drug delivery. J Biomed Mater Res A.

2012 Jan;100(1):141-8. doi: 10.1002/jbm.a.33252. Epub 2011 Oct 14. PubMed PMID:

21997951.

509: Mohajeri SA, Malaekeh-Nikouei B, Sadegh H. Development of a pH-responsive

imprinted polymer for diclofenac and study of its binding properties in organic

and aqueous media. Drug Dev Ind Pharm. 2012 May;38(5):616-22. doi:

10.3109/03639045.2011.621126. Epub 2011 Oct 6. PubMed PMID: 21978326.

510: Chen D, Liu W, Shen Y, Mu H, Zhang Y, Liang R, Wang A, Sun K, Fu F. Effects

of a novel pH-sensitive liposome with cleavable esterase-catalyzed and

pH-responsive double smart mPEG lipid derivative on ABC phenomenon. Int J

Nanomedicine. 2011;6:2053-61. doi: 10.2147/IJN.S24344. Epub 2011 Sep 20. PubMed

PMID: 21976980; PubMed Central PMCID: PMC3181064.

511: Capurso NA, Fahmy TM. Development of a pH-responsive particulate drug

delivery vehicle for localized biologic therapy in inflammatory bowel disease.

Yale J Biol Med. 2011 Sep;84(3):285-8. PubMed PMID: 21966047; PubMed Central

PMCID: PMC3178859.

512: Xiang G, Wu D, He J, Wang X. Acquired pH-responsive and reversible

enrichment of organic dyes by peroxide modified ultrathin TiO2 nanosheets. Chem

Commun (Camb). 2011 Nov 7;47(41):11456-8. doi: 10.1039/c1cc15127d. Epub 2011 Sep

26. PubMed PMID: 21952751.

513: Kim T, Cho EJ, Chae Y, Kim M, Oh A, Jin J, Lee ES, Baik H, Haam S, Suh JS,

Huh YM, Lee K. Urchin-shaped manganese oxide nanoparticles as pH-responsive

activatable T1 contrast agents for magnetic resonance imaging. Angew Chem Int Ed

Engl. 2011 Nov 4;50(45):10589-93. doi: 10.1002/anie.201103108. Epub 2011 Sep 16.

PubMed PMID: 21928456.

514: Jin Y, Ren X, Wang W, Ke L, Ning E, Du L, Bradshaw J. A

5-fluorouracil-loaded pH-responsive dendrimer nanocarrier for tumor targeting.

Int J Pharm. 2011 Nov 28;420(2):378-84. doi: 10.1016/j.ijpharm.2011.08.053. Epub

2011 Sep 8. PubMed PMID: 21925254.

515: Fujii S, Mochizuki M, Aono K, Hamasaki S, Murakami R, Nakamura Y.

pH-responsive aqueous foams stabilized by hairy latex particles. Langmuir. 2011

Nov 1;27(21):12902-9. doi: 10.1021/la203062b. Epub 2011 Sep 29. PubMed PMID:

21910465.

516: Yi JW, Park J, Kim KS, Kim BH. pH-responsive self-duplex of

(Py)A-substituted oligodeoxyadenylate in graphene oxide solution as a molecular

switch. Org Biomol Chem. 2011 Nov 7;9(21):7434-8. doi: 10.1039/c1ob06037f. Epub

2011 Sep 8. PubMed PMID: 21904727.

517: Jiang S, Yao Y, Nie Y, Yang J, Yang J. Investigation of pH-responsive

properties of polymeric micelles with a core-forming block having pendant cyclic

ketal groups. J Colloid Interface Sci. 2011 Dec 1;364(1):264-71. doi:

10.1016/j.jcis.2011.08.013. Epub 2011 Aug 12. PubMed PMID: 21889164.

518: Mahalingam A, Jay JI, Langheinrich K, Shukair S, McRaven MD, Rohan LC,

Herold BC, Hope TJ, Kiser PF. Inhibition of the transport of HIV in vitro using a

pH-responsive synthetic mucin-like polymer system. Biomaterials. 2011

Nov;32(33):8343-55. doi: 10.1016/j.biomaterials.2011.05.001. Epub 2011 Aug 27.

PubMed PMID: 21875751; PubMed Central PMCID: PMC3183097.

519: Khan W, Choi JH, Kim GM, Park SY. Microfluidic formation of pH responsive

5CB droplets decorated with PAA-b-LCP. Lab Chip. 2011 Oct 21;11(20):3493-8. doi:

10.1039/c1lc20402e. Epub 2011 Aug 26. PubMed PMID: 21874196.

520: Xia Y, Wang Y, Wang Y, Tu C, Qiu F, Zhu L, Su Y, Yan D, Zhu B, Zhu X. A

tumor pH-responsive complex: carboxyl-modified hyperbranched polyether and

cis-dichlorodiammineplatinum(II). Colloids Surf B Biointerfaces. 2011 Dec

1;88(2):674-81. doi: 10.1016/j.colsurfb.2011.07.059. Epub 2011 Aug 7. PubMed

PMID: 21872454.

521: Paek K, Chung S, Cho CH, Kim BJ. Fluorescent and pH-responsive diblock

copolymer-coated core-shell CdSe/ZnS particles for a color-displaying,

ratiometric pH sensor. Chem Commun (Camb). 2011 Oct 7;47(37):10272-4. doi:

10.1039/c1cc13848k. Epub 2011 Aug 19. PubMed PMID: 21858291.

522: Zhu X, Lu W, Zhang Y, Reed A, Newton B, Fan Z, Yu H, Ray PC, Gao R.

Imidazole-modified porphyrin as a pH-responsive sensitizer for cancer

photodynamic therapy. Chem Commun (Camb). 2011 Oct 7;47(37):10311-3. doi:

10.1039/c1cc13328d. Epub 2011 Aug 19. PubMed PMID: 21853198.

523: Rizi K, Green RJ, Khutoryanskaya O, Donaldson M, Williams AC. Mechanisms of

burst release from pH-responsive polymeric microparticles. J Pharm Pharmacol.

2011 Sep;63(9):1141-55. doi: 10.1111/j.2042-7158.2011.01322.x. Epub 2011 Jul 6.

PubMed PMID: 21827486.

524: Saha UC, Dhara K, Chattopadhyay B, Mandal SK, Mondal S, Sen S, Mukherjee M,

van Smaalen S, Chattopadhyay P. A new half-condensed Schiff base compound: highly

selective and sensitive pH-responsive fluorescent sensor. Org Lett. 2011 Sep

2;13(17):4510-3. doi: 10.1021/ol201652r. Epub 2011 Aug 9. PubMed PMID: 21827136.

525: Zheng LS, Yang YQ, Guo XD, Sun Y, Qian Y, Zhang LJ. Mesoscopic simulations

on the aggregation behavior of pH-responsive polymeric micelles for drug

delivery. J Colloid Interface Sci. 2011 Nov 1;363(1):114-21. doi:

10.1016/j.jcis.2011.07.040. Epub 2011 Jul 22. PubMed PMID: 21824624.

526: Chang Y, Meng X, Zhao Y, Li K, Zhao B, Zhu M, Li Y, Chen X, Wang J. Novel

water-soluble and pH-responsive anticancer drug nanocarriers: doxorubicin-PAMAM

dendrimer conjugates attached to superparamagnetic iron oxide nanoparticles

(IONPs). J Colloid Interface Sci. 2011 Nov 1;363(1):403-9. doi:

10.1016/j.jcis.2011.06.086. Epub 2011 Jul 23. PubMed PMID: 21821262.

527: He Q, Gao Y, Zhang L, Zhang Z, Gao F, Ji X, Li Y, Shi J. A pH-responsive

mesoporous silica nanoparticles-based multi-drug delivery system for overcoming

multi-drug resistance. Biomaterials. 2011 Oct;32(30):7711-20. doi:

10.1016/j.biomaterials.2011.06.066. Epub 2011 Aug 4. PubMed PMID: 21816467.

528: Yoshitomi T, Hirayama A, Nagasaki Y. The ROS scavenging and renal protective

effects of pH-responsive nitroxide radical-containing nanoparticles.

Biomaterials. 2011 Nov;32(31):8021-8. doi: 10.1016/j.biomaterials.2011.07.014.

Epub 2011 Aug 3. PubMed PMID: 21816462.

529: Yan X, Zhang M, Wei P, Zheng B, Chi X, Ji X, Huang F. pH-responsive assembly

and disassembly of a supramolecular cryptand-based pseudorotaxane driven by π-π

stacking interaction. Chem Commun (Camb). 2011 Sep 21;47(35):9840-2. doi:

10.1039/c1cc13472h. Epub 2011 Aug 2. PubMed PMID: 21808783.

530: Ding D, Pu KY, Li K, Liu B. Conjugated oligoelectrolyte-polyhedral

oligomeric silsesquioxane loaded pH-responsive nanoparticles for targeted

fluorescence imaging of cancer cell nucleus. Chem Commun (Camb). 2011 Sep

21;47(35):9837-9. doi: 10.1039/c1cc13237g. Epub 2011 Aug 2. PubMed PMID:

21808781.

531: Peng T, Lim S. Trimer-based design of pH-responsive protein cage results in

soluble disassembled structures. Biomacromolecules. 2011 Sep 12;12(9):3131-8.

doi: 10.1021/bm2005438. Epub 2011 Jul 28. PubMed PMID: 21797220.

532: Mufti J, Hajarnis S, Shepardson K, Gummadi L, Taylor L, Curthoys NP. Role of

AUF1 and HuR in the pH-responsive stabilization of phosphoenolpyruvate

carboxykinase mRNA in LLC-PK₁-F⁺ cells. Am J Physiol Renal Physiol. 2011

Nov;301(5):F1066-77. doi: 10.1152/ajprenal.00303.2011. Epub 2011 Jul 27. PubMed

PMID: 21795643; PubMed Central PMCID: PMC3213904.

533: Wagdare NA, Marcelis AT, Boom RM, van Rijn CJ. Microcapsules with a pH

responsive polymer: influence of the encapsulated oil on the capsule morphology.

Colloids Surf B Biointerfaces. 2011 Nov 1;88(1):175-80. doi:

10.1016/j.colsurfb.2011.06.028. Epub 2011 Jun 29. PubMed PMID: 21764268.

534: Su J, Chen F, Cryns VL, Messersmith PB. Catechol polymers for pH-responsive,

targeted drug delivery to cancer cells. J Am Chem Soc. 2011 Aug

10;133(31):11850-3. doi: 10.1021/ja203077x. Epub 2011 Jul 19. PubMed PMID:

21751810; PubMed Central PMCID: PMC3149454.

535: Qu K, Ren J, Qu X. pH-responsive, DNA-directed reversible assembly of

graphene oxide. Mol Biosyst. 2011 Sep;7(9):2681-7. doi: 10.1039/c1mb05121k. Epub

2011 Jul 12. PubMed PMID: 21748191.

536: Zhang T, Sturgis TF, Youan BB. pH-responsive nanoparticles releasing

tenofovir intended for the prevention of HIV transmission. Eur J Pharm Biopharm.

2011 Nov;79(3):526-36. doi: 10.1016/j.ejpb.2011.06.007. Epub 2011 Jun 26. PubMed

PMID: 21736940; PubMed Central PMCID: PMC3375322.

537: Popescu MT, Mourtas S, Pampalakis G, Antimisiaris SG, Tsitsilianis C.

pH-responsive hydrogel/liposome soft nanocomposites for tuning drug release.

Biomacromolecules. 2011 Aug 8;12(8):3023-30. doi: 10.1021/bm2006483. Epub 2011

Jul 15. PubMed PMID: 21728314.

538: Liu Q, Yu B, Ye W, Zhou F. Highly selective uptake and release of charged

molecules by pH-responsive polydopamine microcapsules. Macromol Biosci. 2011 Sep

9;11(9):1227-34. doi: 10.1002/mabi.201100061. Epub 2011 Jun 30. PubMed PMID:

21721126.

539: Ge C, Orosz KS, Armstrong NR, Saavedra SS. Poly(aniline) nanowires in

sol-gel coated ITO: a pH-responsive substrate for planar supported lipid

bilayers. ACS Appl Mater Interfaces. 2011 Jul;3(7):2677-85. doi:

10.1021/am2004637. Epub 2011 Jun 27. PubMed PMID: 21707069; PubMed Central PMCID:

PMC3145051.

540: Riedinger A, Pernia Leal M, Deka SR, George C, Franchini IR, Falqui A,

Cingolani R, Pellegrino T. "Nanohybrids" based on pH-responsive hydrogels and

inorganic nanoparticles for drug delivery and sensor applications. Nano Lett.

2011 Aug 10;11(8):3136-41. doi: 10.1021/nl2011627. Epub 2011 Jul 1. PubMed PMID:

21692456.

541: Schlossbauer A, Dohmen C, Schaffert D, Wagner E, Bein T. pH-responsive

release of acetal-linked melittin from SBA-15 mesoporous silica. Angew Chem Int

Ed Engl. 2011 Jul 18;50(30):6828-30. doi: 10.1002/anie.201005120. Epub 2011 Jun

17. PubMed PMID: 21688354.

542: Safaei Nikouei N, Lavasanifar A. Characterization of the thermo- and

pH-responsive assembly of triblock copolymers based on poly(ethylene glycol) and

functionalized poly(ε-caprolactone). Acta Biomater. 2011 Oct;7(10):3708-18. doi:

10.1016/j.actbio.2011.05.035. Epub 2011 Jun 6. PubMed PMID: 21672641.

543: Zhang S, Nelson A, Coldrick Z, Chen R. The effects of substituent grafting

on the interaction of pH-responsive polymers with phospholipid monolayers.

Langmuir. 2011 Jul 5;27(13):8530-9. doi: 10.1021/la105125d. Epub 2011 Jun 9.

PubMed PMID: 21657216.

544: Fujii S, Suzaki M, Armes SP, Dupin D, Hamasaki S, Aono K, Nakamura Y. Liquid

marbles prepared from pH-responsive sterically stabilized latex particles.

Langmuir. 2011 Jul 5;27(13):8067-74. doi: 10.1021/la201317b. Epub 2011 Jun 2.

PubMed PMID: 21631122.

545: He L, Fullenkamp DE, Rivera JG, Messersmith PB. pH responsive self-healing

hydrogels formed by boronate-catechol complexation. Chem Commun (Camb). 2011 Jul

14;47(26):7497-9. doi: 10.1039/c1cc11928a. Epub 2011 Jun 1. PubMed PMID:

21629956; PubMed Central PMCID: PMC4526106.

546: Palanca-Wessels MC, Convertine AJ, Cutler-Strom R, Booth GC, Lee F, Berguig

GY, Stayton PS, Press OW. Anti-CD22 antibody targeting of pH-responsive micelles

enhances small interfering RNA delivery and gene silencing in lymphoma cells. Mol

Ther. 2011 Aug;19(8):1529-37. doi: 10.1038/mt.2011.104. Epub 2011 May 31. PubMed

PMID: 21629223; PubMed Central PMCID: PMC3149160.

547: Giannotti MI, Esteban O, Oliva M, García-Parajo MF, Sanz F. pH-responsive

polysaccharide-based polyelectrolyte complexes as nanocarriers for lysosomal

delivery of therapeutic proteins. Biomacromolecules. 2011 Jul 11;12(7):2524-33.

doi: 10.1021/bm2003384. Epub 2011 Jun 6. PubMed PMID: 21604696.

548: VanBlarcom DS, Peppas NA. Microcantilever sensing arrays from biodegradable,

pH-responsive hydrogels. Biomed Microdevices. 2011 Oct;13(5):829-36. doi:

10.1007/s10544-011-9553-3. PubMed PMID: 21603961.

549: Wang W, Li L, Jin C, Niu Y, Li S, Ma J, Li L, Liu Y, Cai L, Zhao W, Wang PG.

Enzymatic synthesis of a 6-sialyl lactose analogue using a pH-responsive

water-soluble polymer support. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5041-4.

doi: 10.1016/j.bmcl.2011.04.076. Epub 2011 Apr 24. PubMed PMID: 21601456.

550: Park IK, Singha K, Arote RB, Choi YJ, Kim WJ, Cho CS. pH-Responsive Polymers

as Gene Carriers. Macromol Rapid Commun. 2010 Jul 1;31(13):1122-33. doi:

10.1002/marc.200900867. Epub 2010 May 4. PubMed PMID: 21590865.

551: Xing L, Zheng H, Che S. A pH-responsive cleavage route based on a

metal-organic coordination bond. Chemistry. 2011 Jun 20;17(26):7271-5. doi:

10.1002/chem.201003005. Epub 2011 May 12. PubMed PMID: 21567490.

552: Naik SS, Ray JG, Savin DA. Temperature- and pH-responsive self-assembly of

poly(propylene oxide)-b-poly(lysine) block copolymers in aqueous solution.

Langmuir. 2011 Jun 7;27(11):7231-40. doi: 10.1021/la200882f. Epub 2011 May 12.

PubMed PMID: 21563804.

553: Zhao C, He P, Xiao C, Gao X, Zhuang X, Chen X. Synthesis of temperature and

pH-responsive crosslinked micelles from polypeptide-based graft copolymer. J

Colloid Interface Sci. 2011 Jul 15;359(2):436-42. doi:

10.1016/j.jcis.2011.04.037. Epub 2011 Apr 18. PubMed PMID: 21531426.

554: Nunes SP, Behzad AR, Hooghan B, Sougrat R, Karunakaran M, Pradeep N, Vainio

U, Peinemann KV. Switchable pH-responsive polymeric membranes prepared via block

copolymer micelle assembly. ACS Nano. 2011 May 24;5(5):3516-22. doi:

10.1021/nn200484v. Epub 2011 Apr 25. PubMed PMID: 21504167.

555: Kashiwada A, Tsuboi M, Takamura N, Brandenburg E, Matsuda K, Koksch B.

Design and characterization of endosomal-pH-responsive coiled coils for

constructing an artificial membrane fusion system. Chemistry. 2011 May

23;17(22):6179-86. doi: 10.1002/chem.201003392. Epub 2011 Apr 18. PubMed PMID:

21503987.

556: El-Khouri RJ, Bricarello DA, Watkins EB, Kim CY, Miller CE, Patten TE,

Parikh AN, Kuhl TL. pH responsive polymer cushions for probing membrane

environment interactions. Nano Lett. 2011 May 11;11(5):2169-72. doi:

10.1021/nl200832c. Epub 2011 Apr 18. PubMed PMID: 21500840.

557: Albarran B, Hoffman AS, Stayton PS. Efficient Intracellular Delivery of a

Pro-Apoptotic Peptide With A pH-Responsive Carrier. React Funct Polym. 2011 Mar

1;71(3):261-265. PubMed PMID: 21499545; PubMed Central PMCID: PMC3076797.

558: Oberoi HS, Laquer FC, Marky LA, Kabanov AV, Bronich TK. Core cross-linked

block ionomer micelles as pH-responsive carriers for

cis-diamminedichloroplatinum(II). J Control Release. 2011 Jul 15;153(1):64-72.

doi: 10.1016/j.jconrel.2011.03.028. Epub 2011 Apr 8. PubMed PMID: 21497174;

PubMed Central PMCID: PMC3134139.

559: Zhou K, Wang Y, Huang X, Luby-Phelps K, Sumer BD, Gao J. Tunable,

ultrasensitive pH-responsive nanoparticles targeting specific endocytic

organelles in living cells. Angew Chem Int Ed Engl. 2011 Jun 27;50(27):6109-14.

doi: 10.1002/anie.201100884. Epub 2011 Apr 14. PubMed PMID: 21495146; PubMed

Central PMCID: PMC3438661.

560: Tetsch L, Koller C, Dönhöfer A, Jung K. Detection and function of an

intramolecular disulfide bond in the pH-responsive CadC of Escherichia coli. BMC

Microbiol. 2011 Apr 12;11:74. doi: 10.1186/1471-2180-11-74. PubMed PMID:

21486484; PubMed Central PMCID: PMC3096576.

561: Lien le TN, Shiraki T, Dawn A, Tsuchiya Y, Tokunaga D, Tamaru S, Enomoto N,

Hojo J, Shinkai S. A pH-responsive carboxylic β-1,3-glucan polysaccharide for

complexation with polymeric guests. Org Biomol Chem. 2011 Jun 7;9(11):4266-75.

doi: 10.1039/c1ob05114h. Epub 2011 Apr 11. PubMed PMID: 21483941.

562: Iatridi Z, Tsitsilianis C. pH responsive self assemblies from an

A(n)-core-(B-b-C)n heteroarm star block terpolymer bearing oppositely charged

segments. Chem Commun (Camb). 2011 May 21;47(19):5560-2. doi: 10.1039/c0cc05507g.

Epub 2011 Apr 4. PubMed PMID: 21461436.

563: Ren D, Kratz F, Wang SW. Protein nanocapsules containing doxorubicin as a

pH-responsive delivery system. Small. 2011 Apr 18;7(8):1051-60. doi:

10.1002/smll.201002242. Epub 2011 Mar 29. PubMed PMID: 21456086; PubMed Central

PMCID: PMC3118673.

564: Negrini R, Mezzenga R. pH-responsive lyotropic liquid crystals for

controlled drug delivery. Langmuir. 2011 May 3;27(9):5296-303. doi:

10.1021/la200591u. Epub 2011 Mar 31. PubMed PMID: 21452814.

565: Wang L, He X, Guo Y, Xu J, Shao S. pH-Responsive chromogenic-sensing

molecule based on bis(indolyl)methene for the highly selective recognition of

aspartate and glutamate. Beilstein J Org Chem. 2011 Feb 16;7:218-21. doi:

10.3762/bjoc.7.29. PubMed PMID: 21448262; PubMed Central PMCID: PMC3063074.

566: Kar S, Drew MG, Pramanik A. Formation of vesicles through solvent assisted

self-assembly of hydrophobic pentapeptides: encapsulation and pH responsive

release of dyes by the vesicles. Protein Pept Lett. 2011 Sep;18(9):886-97. PubMed

PMID: 21443496.

567: Alhnan MA, Kidia E, Basit AW. Spray-drying enteric polymers from aqueous

solutions: a novel, economic, and environmentally friendly approach to produce

pH-responsive microparticles. Eur J Pharm Biopharm. 2011 Oct;79(2):432-9. doi:

10.1016/j.ejpb.2011.03.015. Epub 2011 Mar 23. PubMed PMID: 21439376.

568: Lynch AL, Chen R, Slater NK. pH-responsive polymers for trehalose loading

and desiccation protection of human red blood cells. Biomaterials. 2011

Jul;32(19):4443-9. doi: 10.1016/j.biomaterials.2011.02.062. Epub 2011 Mar 21.

PubMed PMID: 21421265.

569: Ghosh S, Dey J. Interaction of sodium N-lauroylsarcosinate with

N-alkylpyridinium chloride surfactants: spontaneous formation of pH-responsive,

stable vesicles in aqueous mixtures. J Colloid Interface Sci. 2011 Jun

1;358(1):208-16. doi: 10.1016/j.jcis.2011.02.054. Epub 2011 Mar 1. PubMed PMID:

21420688.

570: Su X, Fricke J, Kavanagh DG, Irvine DJ. In vitro and in vivo mRNA delivery

using lipid-enveloped pH-responsive polymer nanoparticles. Mol Pharm. 2011 Jun

6;8(3):774-87. doi: 10.1021/mp100390w. Epub 2011 Apr 1. PubMed PMID: 21417235;

PubMed Central PMCID: PMC3354687.

571: Yung KY, Schadock-Hewitt AJ, Hunter NP, Bright FV, Baker GA. 'Liquid

litmus': chemosensory pH-responsive photonic ionic liquids. Chem Commun (Camb).

2011 Apr 28;47(16):4775-7. doi: 10.1039/c1cc00065a. Epub 2011 Mar 14. PubMed

PMID: 21399813.

572: Minehara H, Naka K, Tanaka K, Narita A, Chujo Y. Arsonic acid-presenting

superparamagnetic iron oxide for pH-responsive aggregation under slightly acidic

conditions. Bioorg Med Chem. 2011 Apr 1;19(7):2282-6. doi:

10.1016/j.bmc.2011.02.027. Epub 2011 Feb 18. PubMed PMID: 21393003.

573: Mouffouk F, da Costa AM, Martins J, Zourob M, Abu-Salah KM, Alrokayan SA.

Development of a highly sensitive bacteria detection assay using fluorescent

pH-responsive polymeric micelles. Biosens Bioelectron. 2011 Apr 15;26(8):3517-23.

doi: 10.1016/j.bios.2011.01.037. Epub 2011 Mar 5. PubMed PMID: 21382708.

574: He H, Ng DK. A ratiometric near-infrared pH-responsive fluorescent dye based

on distyryl BODIPY. Org Biomol Chem. 2011 Apr 21;9(8):2610-3. doi:

10.1039/c0ob01252a. Epub 2011 Mar 2. PubMed PMID: 21365103.

575: Wei J, Ju XJ, Xie R, Mou CL, Lin X, Chu LY. Novel cationic pH-responsive

poly(N,N-dimethylaminoethyl methacrylate) microcapsules prepared by a

microfluidic technique. J Colloid Interface Sci. 2011 May 1;357(1):101-8. doi:

10.1016/j.jcis.2011.01.105. Epub 2011 Feb 3. PubMed PMID: 21345438.

576: Wang C, Wang G, Wang Z, Zhang X. A pH-responsive superamphiphile based on

dynamic covalent bonds. Chemistry. 2011 Mar 14;17(12):3322-5. doi:

10.1002/chem.201003502. Epub 2011 Feb 21. PubMed PMID: 21341334.

577: Knežević NŽ, Trewyn BG, Lin VS. Light- and pH-responsive release of

doxorubicin from a mesoporous silica-based nanocarrier. Chemistry. 2011 Mar

14;17(12):3338-42. doi: 10.1002/chem.201002960. Epub 2011 Feb 17. PubMed PMID:

21337435.

578: Lee BR, Oh KT, Oh YT, Baik HJ, Park SY, Youn YS, Lee ES. A novel

pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)2 peptide

delivery. Chem Commun (Camb). 2011 Apr 7;47(13):3852-4. doi: 10.1039/c0cc03590d.

Epub 2011 Feb 14. PubMed PMID: 21321691.

579: Lay CL, Tan HR, Lu X, Liu Y. pH-responsive poly(methacrylic acid)-grafted

hollow silica vesicles. Chemistry. 2011 Feb 18;17(8):2504-9. doi:

10.1002/chem.201001403. Epub 2011 Jan 17. PubMed PMID: 21319241.

580: Ye S, Chen S, Wang H, Lu Y. pH-responsive luminescent properties of Ag@PPy

nanoparticles. Phys Chem Chem Phys. 2011 Mar 14;13(10):4668-73. doi:

10.1039/c0cp02184a. Epub 2011 Jan 31. PubMed PMID: 21279225.

581: Ho VH, Slater NK, Chen R. pH-responsive endosomolytic pseudo-peptides for

drug delivery to multicellular spheroids tumour models. Biomaterials. 2011

Apr;32(11):2953-8. doi: 10.1016/j.biomaterials.2011.01.010. Epub 2011 Jan 26.

PubMed PMID: 21272931.

582: Chen KJ, Chiu YL, Chen YM, Ho YC, Sung HW. Intracellularly

monitoring/imaging the release of doxorubicin from pH-responsive nanoparticles

using Förster resonance energy transfer. Biomaterials. 2011 Apr;32(10):2586-92.

doi: 10.1016/j.biomaterials.2010.11.069. Epub 2011 Jan 19. PubMed PMID: 21251711.

583: Verdejo B, Rodríguez-Llansola F, Escuder B, Miravet JF, Ballester P. Sodium

and pH responsive hydrogel formation by the supramolecular system calix[4]pyrrole

derivative/tetramethylammonium cation. Chem Commun (Camb). 2011 Feb

21;47(7):2017-9. doi: 10.1039/c0cc04051g. Epub 2011 Jan 7. PubMed PMID: 21218218.

584: Haneburger I, Eichinger A, Skerra A, Jung K. New insights into the signaling

mechanism of the pH-responsive, membrane-integrated transcriptional activator

CadC of Escherichia coli. J Biol Chem. 2011 Mar 25;286(12):10681-9. doi:

10.1074/jbc.M110.196923. Epub 2011 Jan 7. PubMed PMID: 21216950; PubMed Central

PMCID: PMC3060519.

585: Bradley M, Garcia-Risueño BS. Symmetric and asymmetric adsorption of

pH-responsive gold nanoparticles onto microgel particles and dispersion

characterisation. J Colloid Interface Sci. 2011 Mar 15;355(2):321-7. doi:

10.1016/j.jcis.2010.12.027. Epub 2010 Dec 15. PubMed PMID: 21215415.

586: Erel I, Zhu Z, Zhuk A, Sukhishvili SA. Hydrogen-bonded layer-by-layer films

of block copolymer micelles with pH-responsive cores. J Colloid Interface Sci.

2011 Mar 1;355(1):61-9. doi: 10.1016/j.jcis.2010.11.083. Epub 2010 Dec 5. PubMed

PMID: 21194703.

587: Garbern JC, Minami E, Stayton PS, Murry CE. Delivery of basic fibroblast

growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis

in infarcted myocardium. Biomaterials. 2011 Mar;32(9):2407-16. doi:

10.1016/j.biomaterials.2010.11.075. Epub 2010 Dec 24. PubMed PMID: 21186056;

PubMed Central PMCID: PMC3026890.

588: Kallberg K, Becker K, Bülow L. Application of a pH responsive multimodal

hydrophobic interaction chromatography medium for the analysis of glycosylated

proteins. J Chromatogr A. 2011 Feb 4;1218(5):678-83. doi:

10.1016/j.chroma.2010.11.080. Epub 2010 Dec 7. PubMed PMID: 21185570.

589: Bird R, Freemont TJ, Saunders BR. Hollow polymer particles that are

pH-responsive and redox sensitive: two simple steps to triggered particle

swelling, gelation and disassembly. Chem Commun (Camb). 2011 Feb 7;47(5):1443-5.

doi: 10.1039/c0cc04657d. Epub 2010 Dec 21. PubMed PMID: 21180719.

590: Dan K, Pan R, Ghosh S. Aggregation and pH responsive disassembly of a new

acid-labile surfactant synthesized by thiol-acrylate Michael addition reaction.

Langmuir. 2011 Jan 18;27(2):612-7. doi: 10.1021/la104445h. Epub 2010 Dec 15.

PubMed PMID: 21158399.

591: Gan Q, Lu X, Yuan Y, Qian J, Zhou H, Lu X, Shi J, Liu C. A magnetic,

reversible pH-responsive nanogated ensemble based on Fe3O4 nanoparticles-capped

mesoporous silica. Biomaterials. 2011 Mar;32(7):1932-42. doi:

10.1016/j.biomaterials.2010.11.020. Epub 2010 Dec 4. PubMed PMID: 21131045.

592: Shera JN, Takahashi D, Herrera AI, Prakash O, Sun XS. Morphology and

structural properties of pH-responsive amphiphilic peptides. J Nanosci

Nanotechnol. 2010 Dec;10(12):7981-7. PubMed PMID: 21121287.

593: Broaders KE, Pastine SJ, Grandhe S, Fréchet JM. Acid-degradable solid-walled

microcapsules for pH-responsive burst-release drug delivery. Chem Commun (Camb).

2011 Jan 14;47(2):665-7. doi: 10.1039/c0cc04190d. Epub 2010 Nov 26. PubMed PMID:

21113530.

594: Lee SM, Song Y, Hong BJ, MacRenaris KW, Mastarone DJ, O'Halloran TV, Meade

TJ, Nguyen ST. Modular polymer-caged nanobins as a theranostic platform with

enhanced magnetic resonance relaxivity and pH-responsive drug release. Angew Chem

Int Ed Engl. 2010 Dec 17;49(51):9960-4. doi: 10.1002/anie.201004867. PubMed PMID:

21082634; PubMed Central PMCID: PMC3096927.

595: Jia Y, Fei J, Cui Y, Yang Y, Gao L, Li J. pH-responsive polysaccharide

microcapsules through covalent bonding assembly. Chem Commun (Camb). 2011 Jan

28;47(4):1175-7. doi: 10.1039/c0cc03578e. Epub 2010 Nov 12. PubMed PMID:

21072426.

596: Guo M, Que C, Wang C, Liu X, Yan H, Liu K. Multifunctional superparamagnetic

nanocarriers with folate-mediated and pH-responsive targeting properties for

anticancer drug delivery. Biomaterials. 2011 Jan;32(1):185-94. doi:

10.1016/j.biomaterials.2010.09.077. Epub 2010 Nov 9. PubMed PMID: 21067808.

597: Kashiwada A, Tsuboi M, Matsuda K. Target-selective one-way membrane fusion

system based on a pH-responsive coiled coil assembly at the interface of

liposomal vesicles. Langmuir. 2011 Feb 15;27(4):1403-8. doi: 10.1021/la103908u.

Epub 2010 Nov 8. PubMed PMID: 21058731.

598: Yuan W, Li CM. Exponentially growing layer-by-layer assembly to fabricate

pH-responsive hierarchical nanoporous polymeric film and its superior controlled

release performance. Chem Commun (Camb). 2010 Dec 28;46(48):9161-3. doi:

10.1039/c0cc03267k. Epub 2010 Nov 1. PubMed PMID: 21042599.

599: Chen Y, Su YH, Zheng LM, Xia XH. A pH responsive electrochemical switch

sensor based on Fe(notpH3) [notpH6 =

1,4,7-triazacyclononane-1,4,7-triyl-tris(methylene-phosphonic acid)]. Talanta.

2010 Nov 15;83(1):145-8. doi: 10.1016/j.talanta.2010.08.053. Epub 2010 Sep 24.

PubMed PMID: 21035655.

600: Leng W, Zhou S, You B, Wu L. Formation of sulfonated aromatic ketone

chromophores within styrene-acrylic acid copolymers and their pH-responsive color

change. Langmuir. 2010 Dec 7;26(23):17836-9. doi: 10.1021/la103833x. Epub 2010

Oct 29. PubMed PMID: 21033731.

601: Yang X, Grailer JJ, Rowland IJ, Javadi A, Hurley SA, Matson VZ, Steeber DA,

Gong S. Multifunctional stable and pH-responsive polymer vesicles formed by

heterofunctional triblock copolymer for targeted anticancer drug delivery and

ultrasensitive MR imaging. ACS Nano. 2010 Nov 23;4(11):6805-17. doi:

10.1021/nn101670k. Epub 2010 Oct 19. PubMed PMID: 20958084.

602: Fang M, Long J, Zhao W, Wang L, Chen G. pH-Responsive chitosan-mediated

graphene dispersions. Langmuir. 2010 Nov 16;26(22):16771-4. doi:

10.1021/la102703b. Epub 2010 Oct 11. PubMed PMID: 20936800.

603: Mackay JA, Callahan DJ, Fitzgerald KN, Chilkoti A. Quantitative model of the

phase behavior of recombinant pH-responsive elastin-like polypeptides.

Biomacromolecules. 2010 Nov 8;11(11):2873-9. doi: 10.1021/bm100571j. Epub 2010

Oct 6. PubMed PMID: 20925333; PubMed Central PMCID: PMC3032028.

604: Barea MJ, Jenkins MJ, Gaber MH, Bridson RH. Evaluation of liposomes coated

with a pH responsive polymer. Int J Pharm. 2010 Dec 15;402(1-2):89-94. doi:

10.1016/j.ijpharm.2010.09.028. Epub 2010 Oct 1. PubMed PMID: 20888403.

605: Convertine AJ, Diab C, Prieve M, Paschal A, Hoffman AS, Johnson PH, Stayton

PS. pH-responsive polymeric micelle carriers for siRNA drugs. Biomacromolecules.

2010 Nov 8;11(11):2904-11. doi: 10.1021/bm100652w. Epub 2010 Oct 1. PubMed PMID:

20886830; PubMed Central PMCID: PMC3026907.

606: Rodríguez-Llansola F, Escuder B, Miravet JF, Hermida-Merino D, Hamley IW,

Cardin CJ, Hayes W. Selective and highly efficient dye scavenging by a

pH-responsive molecular hydrogelator. Chem Commun (Camb). 2010 Nov

14;46(42):7960-2. doi: 10.1039/c0cc02338h. Epub 2010 Sep 27. PubMed PMID:

20871912.

607: Lee CH, Cheng SH, Huang IP, Souris JS, Yang CS, Mou CY, Lo LW. Intracellular

pH-responsive mesoporous silica nanoparticles for the controlled release of

anticancer chemotherapeutics. Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8214-9.

doi: 10.1002/anie.201002639. PubMed PMID: 20865709.

608: Gao GH, Lee JW, Nguyen MK, Im GH, Yang J, Heo H, Jeon P, Park TG, Lee JH,

Lee DS. pH-responsive polymeric micelle based on PEG-poly(β-amino ester)/(amido

amine) as intelligent vehicle for magnetic resonance imaging in detection of

cerebral ischemic area. J Control Release. 2011 Oct 10;155(1):11-7. doi:

10.1016/j.jconrel.2010.09.012. Epub 2010 Sep 18. PubMed PMID: 20854855.

609: Lotlikar V, Kedar U, Shidhaye S, Kadam V. pH-responsive dual pulse

multiparticulate dosage form for treatment of rheumatoid arthritis. Drug Dev Ind

Pharm. 2010 Nov;36(11):1295-302. doi: 10.3109/03639041003786185. PubMed PMID:

20849346.

610: Gao W, Chan JM, Farokhzad OC. pH-Responsive nanoparticles for drug delivery.

Mol Pharm. 2010 Dec 6;7(6):1913-20. doi: 10.1021/mp100253e. Epub 2010 Oct 27.

Review. PubMed PMID: 20836539; PubMed Central PMCID: PMC3379544.

611: Martínez-Otero A, Busqué F, Hernando J, Ruiz-Molina D. Structuration of

pH-responsive fluorescent molecules on surfaces by soft lithographic techniques.

Nanoscale. 2010 Sep;2(9):1781-8. doi: 10.1039/c0nr00169d. Epub 2010 Jul 14.

PubMed PMID: 20820710.

612: Rizi K, Green RJ, Donaldson M, Williams AC. Production of pH-responsive

microparticles by spray drying: investigation of experimental parameter effects

on morphological and release properties. J Pharm Sci. 2011 Feb;100(2):566-79.

doi: 10.1002/jps.22291. Epub 2010 Aug 26. PubMed PMID: 20799364.

613: Howard SC, Craig VS, FitzGerald PA, Wanless EJ. Swelling and collapse of an

adsorbed pH-responsive film-forming microgel measured by optical reflectometry

and QCM. Langmuir. 2010 Sep 21;26(18):14615-23. doi: 10.1021/la1023218. PubMed

PMID: 20795665.

614: Lee SM, Ahn RW, Chen F, Fought AJ, O'Halloran TV, Cryns VL, Nguyen ST.

Biological evaluation of pH-responsive polymer-caged nanobins for breast cancer

therapy. ACS Nano. 2010 Sep 28;4(9):4971-8. doi: 10.1021/nn100560p. PubMed PMID:

20738118; PubMed Central PMCID: PMC3650137.

615: Matsuura K, Hayashi H, Murasato K, Kimizuka N. Trigonal tryptophane zipper

as a novel building block for pH-responsive peptide nano-assemblies. Chem Commun

(Camb). 2011 Jan 7;47(1):265-7. doi: 10.1039/c0cc01324b. Epub 2010 Aug 20. PubMed

PMID: 20730134.

616: Jorge AF, Dias RS, Pereira JC, Pais AA. DNA condensation by pH-responsive

polycations. Biomacromolecules. 2010 Sep 13;11(9):2399-406. doi:

10.1021/bm100565r. PubMed PMID: 20718482.

617: El-Sherbiny IM, Smyth HD. Poly(ethylene glycol)-carboxymethyl chitosan-based

pH-responsive hydrogels: photo-induced synthesis, characterization, swelling, and

in vitro evaluation as potential drug carriers. Carbohydr Res. 2010 Sep

23;345(14):2004-12. doi: 10.1016/j.carres.2010.07.026. Epub 2010 Jul 21. PubMed

PMID: 20708174.

618: Ren L, Liu T, Guo J, Guo S, Wang X, Wang W. A smart pH responsive

graphene/polyacrylamide complex via noncovalent interaction. Nanotechnology. 2010

Aug 20;21(33):335701. doi: 10.1088/0957-4484/21/33/335701. Epub 2010 Jul 26.

PubMed PMID: 20657039.

619: Guo M, Yan Y, Liu X, Yan H, Liu K, Zhang H, Cao Y. Multilayer nanoparticles

with a magnetite core and a polycation inner shell as pH-responsive carriers for

drug delivery. Nanoscale. 2010 Mar;2(3):434-41. doi: 10.1039/b9nr00244h. Epub

2009 Dec 21. PubMed PMID: 20644829.

620: Frutos G, Prior-Cabanillas A, París R, Quijada-Garrido I. A novel controlled

drug delivery system based on pH-responsive hydrogels included in soft gelatin

capsules. Acta Biomater. 2010 Dec;6(12):4650-6. doi:

10.1016/j.actbio.2010.07.018. Epub 2010 Jul 17. PubMed PMID: 20643229.

621: Lee E, Kim K, Choi M, Lee Y, Park JW, Kim B. Development of smart delivery

system for ascorbic acid using pH-responsive P(MAA-co-EGMA) hydrogel

microparticles. Drug Deliv. 2010 Nov;17(8):573-80. doi:

10.3109/10717544.2010.500636. PubMed PMID: 20626233.

622: Koo H, Lee H, Lee S, Min KH, Kim MS, Lee DS, Choi Y, Kwon IC, Kim K, Jeong

SY. In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive

polymeric micelles. Chem Commun (Camb). 2010 Aug 21;46(31):5668-70. doi:

10.1039/c0cc01413c. Epub 2010 Jul 9. PubMed PMID: 20623050.

623: Sonaje K, Lin KJ, Wey SP, Lin CK, Yeh TH, Nguyen HN, Hsu CW, Yen TC, Juang

JH, Sung HW. Biodistribution, pharmacodynamics and pharmacokinetics of insulin

analogues in a rat model: Oral delivery using pH-responsive nanoparticles vs.

subcutaneous injection. Biomaterials. 2010 Sep;31(26):6849-58. doi:

10.1016/j.biomaterials.2010.05.042. Epub 2010 Jun 17. PubMed PMID: 20619787.

624: Guo W, Wang J, Lee SJ, Dong F, Park SS, Ha CS. A general pH-responsive

supramolecular nanovalve based on mesoporous organosilica hollow nanospheres.

Chemistry. 2010 Aug 2;16(29):8641-6. doi: 10.1002/chem.201000980. PubMed PMID:

20593447.

625: Moglianetti M, Webster JR, Edmondson S, Armes SP, Titmuss S. Neutron

reflectivity study of the structure of pH-responsive polymer brushes grown from a

macroinitiator at the sapphire-water interface. Langmuir. 2010 Aug

3;26(15):12684-9. doi: 10.1021/la101550w. PubMed PMID: 20583764.

626: Guan B, Zou F, Zhi J. Nanodiamond as the pH-responsive vehicle for an

anticancer drug. Small. 2010 Jul 19;6(14):1514-9. doi: 10.1002/smll.200902305.

PubMed PMID: 20568258.

627: Cheng Z, Chen AK, Lee HY, Tsourkas A. Examination of folate-targeted

liposomes with encapsulated poly(2-propylacrylic acid) as a pH-responsive

nanoplatform for cytosolic drug delivery. Small. 2010 Jul 5;6(13):1398-401. doi:

10.1002/smll.201000347. PubMed PMID: 20564486.

628: Lee M, Gubernator NG, Sulzer D, Sames D. Development of pH-responsive

fluorescent false neurotransmitters. J Am Chem Soc. 2010 Jul 7;132(26):8828-30.

doi: 10.1021/ja101740k. PubMed PMID: 20540519; PubMed Central PMCID: PMC2923472.

629: Leblond J, Gao H, Petitjean A, Leroux JC. pH-Responsive molecular tweezers.

J Am Chem Soc. 2010 Jun 30;132(25):8544-5. doi: 10.1021/ja103153t. PubMed PMID:

20524610.

630: Chen X, Chen S, Wang J. A pH-responsive

poly(N-isopropylacrylamide-co-acrylic acid) hydrogel for the selective isolation

of hemoglobin from human blood. Analyst. 2010 Jul;135(7):1736-41. doi:

10.1039/c000465k. Epub 2010 May 17. PubMed PMID: 20480063.

631: Mahkam M, Vakhshouri L. Colon-specific drug delivery behavior of

pH-responsive PMAA/perlite composite. Int J Mol Sci. 2010 Apr 12;11(4):1546-56.

doi: 10.3390/ijms11041546. PubMed PMID: 20480034; PubMed Central PMCID:

PMC2871130.

632: Gao GH, Im GH, Kim MS, Lee JW, Yang J, Jeon H, Lee JH, Lee DS.

Magnetite-nanoparticle-encapsulated pH-responsive polymeric micelle as an MRI

probe for detecting acidic pathologic areas. Small. 2010 Jun 6;6(11):1201-4. doi:

10.1002/smll.200902317. PubMed PMID: 20449849.

633: Adams ML, Rao VM, Thakur A, Hussain MA. Colloidal phase behavior of

pH-responsive, amphiphilic PEGylated poly(carboxylic acid)s and effect on kinetic

solubility under acidic conditions. Pharm Dev Technol. 2010 Jun;15(3):266-75.

doi: 10.3109/10837450903170772. PubMed PMID: 22716467.

634: Jiang XJ, Lo PC, Yeung SL, Fong WP, Ng DK. A pH-responsive fluorescence

probe and photosensitiser based on a tetraamino silicon(IV) phthalocyanine. Chem

Commun (Camb). 2010 May 14;46(18):3188-90. doi: 10.1039/c000605j. Epub 2010 Mar

16. PubMed PMID: 20424769.

635: Wang D, Chen L. Temperature and pH-responsive "smart" carbon nanotube

dispersions. Methods Mol Biol. 2010;625:27-38. doi: 10.1007/978-1-60761-579-8_4.

PubMed PMID: 20422379.

636: Swann JM, Bras W, Topham PD, Howse JR, Ryan AJ. Effect of the Hofmeister

anions upon the swelling of a self-assembled pH-responsive hydrogel. Langmuir.

2010 Jun 15;26(12):10191-7. doi: 10.1021/la100339f. PubMed PMID: 20394380.

637: Deka SR, Quarta A, Di Corato R, Falqui A, Manna L, Cingolani R, Pellegrino

T. Acidic pH-responsive nanogels as smart cargo systems for the simultaneous

loading and release of short oligonucleotides and magnetic nanoparticles.

Langmuir. 2010 Jun 15;26(12):10315-24. doi: 10.1021/la1004819. PubMed PMID:

20355740.

638: Wu Y, Chakrabortty S, Gropeanu RA, Wilhelmi J, Xu Y, Er KS, Kuan SL, Koynov

K, Chan Y, Weil T. pH-Responsive quantum dots via an albumin polymer surface

coating. J Am Chem Soc. 2010 Apr 14;132(14):5012-4. doi: 10.1021/ja909570v.

PubMed PMID: 20302298.

639: Truong MY, Dutta NK, Choudhury NR, Kim M, Elvin CM, Hill AJ, Thierry B,

Vasilev K. A pH-responsive interface derived from resilin-mimetic protein

Rec1-resilin. Biomaterials. 2010 May;31(15):4434-46. doi:

10.1016/j.biomaterials.2010.02.019. PubMed PMID: 20223516.

640: Li W, Gandra N, Ellis ED, Courtney S, Li S, Butler E, Gao R. pH-responsive,

TiO2-attached porphyrin for singlet oxygen production in an aqueous solution. ACS

Appl Mater Interfaces. 2009 Aug;1(8):1778-84. doi: 10.1021/am9003039. PubMed

PMID: 20209036; PubMed Central PMCID: PMC2832330.

641: Boysen JH, Subramanian S, Mitchell AP. Intervention of Bro1 in pH-responsive

Rim20 localization in Saccharomyces cerevisiae. Eukaryot Cell. 2010

Apr;9(4):532-8. doi: 10.1128/EC.00027-10. Epub 2010 Feb 26. PubMed PMID:

20190076; PubMed Central PMCID: PMC2863415.

642: Min KH, Kim JH, Bae SM, Shin H, Kim MS, Park S, Lee H, Park RW, Kim IS, Kim

K, Kwon IC, Jeong SY, Lee DS. Tumoral acidic pH-responsive MPEG-poly(beta-amino

ester) polymeric micelles for cancer targeting therapy. J Control Release. 2010

Jun 1;144(2):259-66. doi: 10.1016/j.jconrel.2010.02.024. Epub 2010 Feb 24. PubMed

PMID: 20188131.

643: Li Z, Wang J, Chen J, Lei W, Wang X, Zhang B. pH-responsive silica

nanoparticles for controllable 1O2 generation. Nanotechnology. 2010 Mar

19;21(11):115102. doi: 10.1088/0957-4484/21/11/115102. Epub 2010 Feb 22. PubMed

PMID: 20173245.

644: Yang X, Grailer JJ, Pilla S, Steeber DA, Gong S. Tumor-targeting,

pH-responsive, and stable unimolecular micelles as drug nanocarriers for targeted

cancer therapy. Bioconjug Chem. 2010 Mar 17;21(3):496-504. doi:

10.1021/bc900422j. Epub 2010 Feb 17. PubMed PMID: 20163170.

645: Cervantes-Chávez JA, Ortiz-Castellanos L, Tejeda-Sartorius M, Gold S,

Ruiz-Herrera J. Functional analysis of the pH responsive pathway Pal/Rim in the

phytopathogenic basidiomycete Ustilago maydis. Fungal Genet Biol. 2010

May;47(5):446-57. doi: 10.1016/j.fgb.2010.02.004. Epub 2010 Feb 12. PubMed PMID:

20153837.

646: O'Lenick TG, Jiang X, Zhao B. Thermosensitive aqueous gels with tunable

sol-gel transition temperatures from thermo- and pH-responsive hydrophilic ABA

triblock copolymer. Langmuir. 2010 Jun 1;26(11):8787-96. doi: 10.1021/la9045308.

PubMed PMID: 20099880.

647: Liu R, Zhang Y, Zhao X, Agarwal A, Mueller LJ, Feng P. pH-responsive

nanogated ensemble based on gold-capped mesoporous silica through an acid-labile

acetal linker. J Am Chem Soc. 2010 Feb 10;132(5):1500-1. doi: 10.1021/ja907838s.

PubMed PMID: 20085351.

648: Benoit DS, Henry SM, Shubin AD, Hoffman AS, Stayton PS. pH-responsive

polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to

doxorubicin via knockdown of polo-like kinase 1. Mol Pharm. 2010 Apr

5;7(2):442-55. doi: 10.1021/mp9002255. PubMed PMID: 20073508; PubMed Central

PMCID: PMC2920053.

649: Wu XL, Kim JH, Koo H, Bae SM, Shin H, Kim MS, Lee BH, Park RW, Kim IS, Choi

K, Kwon IC, Kim K, Lee DS. Tumor-targeting peptide conjugated pH-responsive

micelles as a potential drug carrier for cancer therapy. Bioconjug Chem. 2010 Feb

17;21(2):208-13. doi: 10.1021/bc9005283. PubMed PMID: 20073455.

650: Mi L, Bernards MT, Cheng G, Yu Q, Jiang S. pH responsive properties of

non-fouling mixed-charge polymer brushes based on quaternary amine and carboxylic

acid monomers. Biomaterials. 2010 Apr;31(10):2919-25. doi:

10.1016/j.biomaterials.2009.12.038. Epub 2010 Jan 4. PubMed PMID: 20045182.

651: Zhu X, Liu Y, Huang J, Li G. A pH-responsive gate fabricated with

nanochannels and nanoparticles. Chemistry. 2010 Feb 1;16(5):1441-4. doi:

10.1002/chem.200902783. PubMed PMID: 20039351.

652: Imoto T, Kida T, Matsusaki M, Akashi M. Preparation and unique pH-responsive

properties of novel biodegradable nanocapsules composed of poly(gamma-glutamic

acid) and chitosan as weak polyelectrolytes. Macromol Biosci. 2010 Mar

10;10(3):271-7. doi: 10.1002/mabi.200900272. PubMed PMID: 19998357.

653: Dehousse V, Garbacki N, Colige A, Evrard B. Development of pH-responsive

nanocarriers using trimethylchitosans and methacrylic acid copolymer for siRNA

delivery. Biomaterials. 2010 Mar;31(7):1839-49. doi:

10.1016/j.biomaterials.2009.11.028. Epub 2009 Nov 30. PubMed PMID: 19948356.

654: Xu JX, Tang JB, Zhao LH, Shen YQ. [Advances in the study of tumor

pH-responsive polymeric micelles for cancer drug targeting delivery]. Yao Xue Xue

Bao. 2009 Dec;44(12):1328-35. Review. Chinese. PubMed PMID: 21351464.

655: Nechooshtan G, Elgrably-Weiss M, Sheaffer A, Westhof E, Altuvia S. A

pH-responsive riboregulator. Genes Dev. 2009 Nov 15;23(22):2650-62. doi:

10.1101/gad.552209. PubMed PMID: 19933154; PubMed Central PMCID: PMC2779765.

656: Jorge AF, Sarraguça JM, Dias RS, Pais AA. Polyelectrolyte compaction by

pH-responsive agents. Phys Chem Chem Phys. 2009 Dec 14;11(46):10890-8. doi:

10.1039/b914159f. Epub 2009 Oct 13. PubMed PMID: 19924323.

657: Murtagh J, Frimannsson DO, O'Shea DF. Azide conjugatable and pH responsive

near-infrared fluorescent imaging probes. Org Lett. 2009 Dec 3;11(23):5386-9.

doi: 10.1021/ol902140v. PubMed PMID: 19883098.

658: Tauk L, Schröder AP, Decher G, Giuseppone N. Hierarchical functional

gradients of pH-responsive self-assembled monolayers using dynamic covalent

chemistry on surfaces. Nat Chem. 2009 Nov;1(8):649-56. doi: 10.1038/nchem.400.

Epub 2009 Oct 23. PubMed PMID: 21378957.

659: Obata Y, Tajima S, Takeoka S. Evaluation of pH-responsive liposomes

containing amino acid-based zwitterionic lipids for improving intracellular drug

delivery in vitro and in vivo. J Control Release. 2010 Mar 3;142(2):267-76. doi:

10.1016/j.jconrel.2009.10.023. Epub 2009 Oct 25. PubMed PMID: 19861141.

660: Suedee R, Jantarat C, Lindner W, Viernstein H, Songkro S, Srichana T.

Development of a pH-responsive drug delivery system for

enantioselective-controlled delivery of racemic drugs. J Control Release. 2010

Feb 25;142(1):122-31. doi: 10.1016/j.jconrel.2009.10.011. Epub 2009 Oct 23.

PubMed PMID: 19857533.

661: Hua X, Yuan X, Wilhelmus KR. A fungal pH-responsive signaling pathway

regulating Aspergillus adaptation and invasion into the cornea. Invest Ophthalmol

Vis Sci. 2010 Mar;51(3):1517-23. doi: 10.1167/iovs.09-4348. Epub 2009 Oct 22.

PubMed PMID: 19850840; PubMed Central PMCID: PMC2868430.

662: Chen Q, Lv Y, Zhang D, Zhang G, Liu C, Zhu D. Cysteine and pH-responsive

hydrogel based on a saccharide derivative with an aldehyde group. Langmuir. 2010

Mar 2;26(5):3165-8. doi: 10.1021/la903102z. PubMed PMID: 19842630.

663: Liechty WB, Chen R, Farzaneh F, Tavassoli M, Slater NK. Synthetic

pH-Responsive Polymers for Protein Transduction. Adv Mater. 2009 Oct

19;21(38-39):3910-3914. PubMed PMID: 22427722; PubMed Central PMCID: PMC3303159.

664: Akamatsu K, Shimada M, Tsuruoka T, Nawafune H, Fujii S, Nakamura Y.

Synthesis of pH-responsive nanocomposite microgels with size-controlled gold

nanoparticles from ion-doped, lightly cross-linked poly(vinylpyridine). Langmuir.

2010 Jan 19;26(2):1254-9. doi: 10.1021/la902450c. PubMed PMID: 19817404.

665: Khashab NM, Belowich ME, Trabolsi A, Friedman DC, Valente C, Lau Y, Khatib

HA, Zink JI, Stoddart JF. pH-responsive mechanised nanoparticles gated by

semirotaxanes. Chem Commun (Camb). 2009 Sep 28;(36):5371-3. doi:

10.1039/b910431c. Epub 2009 Aug 18. PubMed PMID: 19724788.

666: Pan H, Zimmerman T, Zakhaleva J, Abrahams JM, Jiang H, Chen W. Embolization

of a common carotid aneurysm with rhVEGF coupled to a pH-responsive chitosan in a

rat model. J Neurosurg. 2010 Mar;112(3):658-65. doi: 10.3171/2009.1.JNS08411.

PubMed PMID: 19698048.

667: Chen J, Chu M, Koulajian K, Wu XY, Giacca A, Sun Y. A monolithic polymeric

microdevice for pH-responsive drug delivery. Biomed Microdevices. 2009

Dec;11(6):1251-7. doi: 10.1007/s10544-009-9344-2. PubMed PMID: 19672717.

668: Kobayashi H, Nishikawa M, Sakamoto C, Nishio T, Kanazawa H, Okano T. Dual

temperature- and pH-responsive fluorescence molecular probe for cellular imaging

utilizing a PNIPAAm-fluorescein copolymer. Anal Sci. 2009 Aug;25(8):1043-7.

PubMed PMID: 19667485.

669: Chan AW, Neufeld RJ. Modeling the controllable pH-responsive swelling and

pore size of networked alginate based biomaterials. Biomaterials. 2009

Oct;30(30):6119-29. doi: 10.1016/j.biomaterials.2009.07.034. Epub 2009 Aug 5.

PubMed PMID: 19660810.

670: Shera JN, Sun XS. Effect of peptide sequence on surface properties and

self-assembly of an amphiphilic pH-responsive peptide. Biomacromolecules. 2009

Sep 14;10(9):2446-50. doi: 10.1021/bm900388b. PubMed PMID: 19642669.

671: Chen R, Khormaee S, Eccleston ME, Slater NK. Effect of L-leucine graft

content on aqueous solution behavior and membrane-lytic activity of a

pH-responsive pseudopeptide. Biomacromolecules. 2009 Sep 14;10(9):2601-8. doi:

10.1021/bm900534j. PubMed PMID: 19642668.

672: Zhao L, Nakayama T, Tomimoto H, Shingaya Y, Huang Q. Functionalization of

carbon nanotubes with a pH-responsive molecule to produce a pH sensor.

Nanotechnology. 2009 Aug 12;20(32):325501. doi: 10.1088/0957-4484/20/32/325501.

Epub 2009 Jul 21. PubMed PMID: 19620767.

673: Schmidt V, Borsali R, Giacomelli C. Aggregation of a versatile triblock

copolymer into pH-responsive cross-linkable nanostructures in both organic and

aqueous media. Langmuir. 2009 Dec 1;25(23):13361-7. doi: 10.1021/la901937p.

PubMed PMID: 19606885.

674: Chia KK, Rubner MF, Cohen RE. pH-responsive reversibly swellable nanotube

arrays. Langmuir. 2009 Dec 15;25(24):14044-52. doi: 10.1021/la9015959. PubMed

PMID: 19588941.

675: Kim BS, Lee HI, Min Y, Poon Z, Hammond PT. Hydrogen-bonded multilayer of

pH-responsive polymeric micelles with tannic acid for surface drug delivery. Chem

Commun (Camb). 2009 Jul 28;(28):4194-6. doi: 10.1039/b908688a. Epub 2009 Jun 16.

PubMed PMID: 19585018; PubMed Central PMCID: PMC3965301.

676: Wei X, Qi L, Yang G, Wang F. Preparation and characterization of monolithic

column by grafting pH-responsive polymer. Talanta. 2009 Aug 15;79(3):739-45. doi:

10.1016/j.talanta.2009.04.062. Epub 2009 May 7. PubMed PMID: 19576439.

677: Hinrichs K, Aulich D, Ionov L, Esser N, Eichhorn KJ, Motornov M, Stamm M,

Minko S. Chemical and structural changes in a pH-responsive mixed polyelectrolyte

brush studied by infrared ellipsometry. Langmuir. 2009 Sep 15;25(18):10987-91.

doi: 10.1021/la901219f. PubMed PMID: 19572506.

678: Betancourt T, Pardo J, Soo K, Peppas NA. Characterization of pH-responsive

hydrogels of poly(itaconic acid-g-ethylene glycol) prepared by UV-initiated free

radical polymerization as biomaterials for oral delivery of bioactive agents. J

Biomed Mater Res A. 2010 Apr;93(1):175-88. doi: 10.1002/jbm.a.32510. PubMed PMID:

19536838; PubMed Central PMCID: PMC2826507.

679: Tan BH, Gudipati CS, Hussain H, He C, Liu Y, Davis TP. Synthesis and

Self-Assembly of pH-Responsive Amphiphilic Poly(dimethylaminoethyl

methacrylate)-block-Poly(pentafluorostyrene) Block Copolymer in Aqueous Solution.

Macromol Rapid Commun. 2009 Jun 17;30(12):1002-8. doi: 10.1002/marc.200800799.

Epub 2009 Apr 21. PubMed PMID: 21706562.

680: Nilkumhang S, Basit AW. The robustness and flexibility of an emulsion

solvent evaporation method to prepare pH-responsive microparticles. Int J Pharm.

2009 Jul 30;377(1-2):135-41. doi: 10.1016/j.ijpharm.2009.03.024. Epub 2009 Apr 1.

PubMed PMID: 19515519.

681: Kendall RA, Alhnan MA, Nilkumhang S, Murdan S, Basit AW. Fabrication and in

vivo evaluation of highly pH-responsive acrylic microparticles for targeted

gastrointestinal delivery. Eur J Pharm Sci. 2009 Jun 28;37(3-4):284-90. doi:

10.1016/j.ejps.2009.02.015. Epub 2009 Mar 6. PubMed PMID: 19491017.

682: Sun G, Chang Y, Li S, Li Q, Xu R, Gu J, Wang E. pH-responsive controlled

release of antitumour-active polyoxometalate from mesoporous silica materials.

Dalton Trans. 2009 Jun 21;(23):4481-7. doi: 10.1039/b901133a. Epub 2009 Apr 1.

PubMed PMID: 19488446.

683: Chen W, Meng F, Li F, Ji SJ, Zhong Z. pH-responsive biodegradable micelles

based on acid-labile polycarbonate hydrophobe: synthesis and triggered drug

release. Biomacromolecules. 2009 Jul 13;10(7):1727-35. doi: 10.1021/bm900074d.

Epub 2009 May 26. PubMed PMID: 19469499.

684: Criscione JM, Le BL, Stern E, Brennan M, Rahner C, Papademetris X, Fahmy TM.

Self-assembly of pH-responsive fluorinated dendrimer-based particulates for drug

delivery and noninvasive imaging. Biomaterials. 2009 Aug;30(23-24):3946-55. doi:

10.1016/j.biomaterials.2009.04.014. Epub 2009 May 13. PubMed PMID: 19443028.

685: Liu C, Hillmyer MA, Lodge TP. Multicompartment micelles from pH-responsive

miktoarm star block terpolymers. Langmuir. 2009 Dec 15;25(24):13718-25. doi:

10.1021/la900845u. PubMed PMID: 19438177.

686: Fujii S, Dupin D, Araki T, Armes SP, Ade H. First direct imaging of

electrolyte-induced deswelling behavior of pH-responsive microgels in aqueous

media using scanning transmission X-ray microscopy. Langmuir. 2009 Mar

3;25(5):2588-92. doi: 10.1021/la804212y. PubMed PMID: 19437683.

687: Lin JJ, Hsu YC. Temperature and pH-responsive properties of

poly(styrene-co-maleic anhydride)-grafting poly(oxypropylene)-amines. J Colloid

Interface Sci. 2009 Aug 1;336(1):82-9. doi: 10.1016/j.jcis.2009.03.064. Epub 2009

Apr 7. PubMed PMID: 19398109.

688: Dowling MB, Lee JH, Raghavan SR. pH-responsive jello: gelatin gels

containing fatty acid vesicles. Langmuir. 2009 Aug 4;25(15):8519-25. doi:

10.1021/la804159g. PubMed PMID: 19317424.

689: Lin YH, Chang CH, Wu YS, Hsu YM, Chiou SF, Chen YJ. Development of

pH-responsive chitosan/heparin nanoparticles for stomach-specific

anti-Helicobacter pylori therapy. Biomaterials. 2009 Jul;30(19):3332-42. doi:

10.1016/j.biomaterials.2009.02.036. Epub 2009 Mar 18. PubMed PMID: 19299008.

690: Yusa S, Sugahara M, Endo T, Morishima Y. Preparation and characterization of

a pH-responsive nanogel based on a photo-cross-linked micelle formed from block

copolymers with controlled structure. Langmuir. 2009 May 5;25(9):5258-65. doi:

10.1021/la803878s. PubMed PMID: 19292434.

691: Benetti EM, Chung HJ, Vancso GJ. pH Responsive Polymeric Brush

Nanostructures: Preparation and Characterization by Scanning Probe Oxidation and

Surface Initiated Polymerization. Macromol Rapid Commun. 2009 Mar 19;30(6):411-7.

doi: 10.1002/marc.200800628. Epub 2009 Jan 20. PubMed PMID: 21706617.

692: Ghosh A, Dey J. pH-responsive and thermoreversible hydrogels of

N-(2-hydroxyalkyl)-L-valine amphiphiles. Langmuir. 2009 Aug 4;25(15):8466-72.

doi: 10.1021/la803959j. PubMed PMID: 19290657.

693: He E, Yue CY, Tam KC. Association behavior of star-shaped pH-responsive

block copolymer: four-arm poly(ethylene oxide)-b-poly(methacrylic acid) in

aqueous medium. Langmuir. 2009 May 5;25(9):4892-9. doi: 10.1021/la804056p. PubMed

PMID: 19290652.

694: Riley JM, Aggeli A, Koopmans RJ, McPherson MJ. Bioproduction and

characterization of a pH responsive self-assembling peptide. Biotechnol Bioeng.

2009 Jun 1;103(2):241-51. doi: 10.1002/bit.22274. PubMed PMID: 19266471.

695: Hu Y, Atukorale PU, Lu JJ, Moon JJ, Um SH, Cho EC, Wang Y, Chen J, Irvine

DJ. Cytosolic delivery mediated via electrostatic surface binding of protein,

virus, or siRNA cargos to pH-responsive core-shell gel particles.

Biomacromolecules. 2009 Apr 13;10(4):756-65. doi: 10.1021/bm801199z. PubMed PMID:

19239276; PubMed Central PMCID: PMC2769516.

696: Liu H, Li C, Liu H, Liu S. pH-responsive supramolecular self-assembly of

well-defined zwitterionic ABC miktoarm star terpolymers. Langmuir. 2009 Apr

21;25(8):4724-34. doi: 10.1021/la803813r. PubMed PMID: 19239225.

697: Rafati H, Talebpour Z, Adlnasab L, Ebrahimi SN. Quality by design:

optimization of a liquid filled pH-responsive macroparticles using Draper-Lin

composite design. J Pharm Sci. 2009 Jul;98(7):2401-11. doi: 10.1002/jps.21625.

PubMed PMID: 19226624.

698: Liu Y, Bryantsev VS, Diallo MS, Goddard WA 3rd. PAMAM dendrimers undergo pH

responsive conformational changes without swelling. J Am Chem Soc. 2009 Mar

4;131(8):2798-9. doi: 10.1021/ja8100227. PubMed PMID: 19199433.

699: Wang Y, Zhang J, Zhang W, Zhang M. Pd-catalyzed C-C cross-coupling reactions

within a thermoresponsive and pH-responsive and chelating polymeric hydrogel. J

Org Chem. 2009 Mar 6;74(5):1923-31. doi: 10.1021/jo802427k. PubMed PMID:

19173610.

700: Li Y, Zamble DB. pH-responsive DNA-binding activity of Helicobacter pylori

NikR. Biochemistry. 2009 Mar 24;48(11):2486-96. doi: 10.1021/bi801742r. PubMed

PMID: 19170600.

701: Chen R, Khormaee S, Eccleston ME, Slater NK. The role of hydrophobic amino

acid grafts in the enhancement of membrane-disruptive activity of pH-responsive

pseudo-peptides. Biomaterials. 2009 Apr;30(10):1954-61. doi:

10.1016/j.biomaterials.2008.12.036. Epub 2009 Jan 12. PubMed PMID: 19138797;

PubMed Central PMCID: PMC3038271.

702: Xu S, Luo Y, Graeser R, Warnecke A, Kratz F, Hauff P, Licha K, Haag R.

Development of pH-responsive core-shell nanocarriers for delivery of therapeutic

and diagnostic agents. Bioorg Med Chem Lett. 2009 Feb 1;19(3):1030-4. doi:

10.1016/j.bmcl.2008.01.043. Epub 2008 Jan 18. PubMed PMID: 19097889.

703: Farmer TG Jr, Edgar TF, Peppas NA. In Vivo Simulations of the Intravenous

Dynamics of Submicron Particles of pH-Responsive Cationic Hydrogels in Diabetic

Patients. Ind Eng Chem Res. 2008 Dec 17;47(24):10053-10063. PubMed PMID:

20428328; PubMed Central PMCID: PMC2860336.

704: Lin Y, Han X, Huang J, Fu H, Yu C. A facile route to design pH-responsive

viscoelastic wormlike micelles: Smart use of hydrotropes. J Colloid Interface

Sci. 2009 Feb 15;330(2):449-55. doi: 10.1016/j.jcis.2008.10.071. Epub 2008 Dec 6.

PubMed PMID: 19059596.

705: Martínez-Otero A, Hernando J, Ruiz-Molina D, Maspoch D. pH-responsive

fluorescent nanoarrays fabricated by direct-write parallel dip-pen

nanolithography. Small. 2008 Dec;4(12):2131-5. doi: 10.1002/smll.200800481.

PubMed PMID: 19003822.

706: Wang Y, Wang Y, Wu G, Fan Y, Ma J. pH-responsive self-assembly and

conformational transition of partially propyl-esterified

poly(alpha,beta-L-aspartic acid) as amphiphilic biodegradable polyanion. Colloids

Surf B Biointerfaces. 2009 Jan 1;68(1):13-9. doi: 10.1016/j.colsurfb.2008.08.026.

Epub 2008 Sep 16. PubMed PMID: 18990548.

707: Wen Y, Feng J, Scott DR, Marcus EA, Sachs G. The pH-responsive regulon of

HP0244 (FlgS), the cytoplasmic histidine kinase of Helicobacter pylori. J

Bacteriol. 2009 Jan;191(2):449-60. doi: 10.1128/JB.01219-08. Epub 2008 Oct 31.

PubMed PMID: 18978046; PubMed Central PMCID: PMC2620809.

708: Li J, Stöver HD. Doubly pH-responsive pickering emulsion. Langmuir. 2008 Dec

2;24(23):13237-40. doi: 10.1021/la802619m. PubMed PMID: 18973315.

709: Ma Q, Chen M, Yin HR, Shi ZG, Feng YQ. Preparation of pH-responsive

stationary phase for reversed-phase liquid chromatography and hydrophilic

interaction chromatography. J Chromatogr A. 2008 Nov 28;1212(1-2):61-7. doi:

10.1016/j.chroma.2008.10.007. Epub 2008 Oct 10. PubMed PMID: 18950778.

710: Balof SL, P'pool SJ, Berger NJ, Valente EJ, Shiller AM, Schanz HJ. Olefin

metathesis catalysts bearing a pH-responsive NHC ligand: a feasible approach to

catalyst separation from RCM products. Dalton Trans. 2008 Nov 14;(42):5791-9.

doi: 10.1039/b809793c. Epub 2008 Sep 12. PubMed PMID: 18941667.

711: Orts Gil G, Losik M, Schlaad H, Drechsler M, Hellweg T. Properties of

pH-responsive mixed aggregates of polystyrene-block-poly(L-lysine) and nonionic

surfactant in solution and adsorbed at a solid surface. Langmuir. 2008 Nov

18;24(22):12823-8. doi: 10.1021/la8017562. Epub 2008 Oct 17. PubMed PMID:

18925753.

712: Lin YH, Sonaje K, Lin KM, Juang JH, Mi FL, Yang HW, Sung HW.

Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral

delivery of protein drugs. J Control Release. 2008 Dec 8;132(2):141-9. doi:

10.1016/j.jconrel.2008.08.020. Epub 2008 Sep 9. PubMed PMID: 18817821.

713: Tekade RK, Dutta T, Gajbhiye V, Jain NK. Exploring dendrimer towards dual

drug delivery: pH responsive simultaneous drug-release kinetics. J Microencapsul.

2009 Jun;26(4):287-96. doi: 10.1080/02652040802312572. PubMed PMID: 18791906.

714: Schellekens RC, Stellaard F, Mitrovic D, Stuurman FE, Kosterink JG, Frijlink

HW. Pulsatile drug delivery to ileo-colonic segments by structured incorporation

of disintegrants in pH-responsive polymer coatings. J Control Release. 2008 Dec

8;132(2):91-8. doi: 10.1016/j.jconrel.2008.08.008. Epub 2008 Aug 23. PubMed PMID:

18775755.

715: Chen R, Yue Z, Eccleston ME, Slater NK. Aqueous solution behaviour and

membrane disruptive activity of pH-responsive PEGylated pseudo-peptides and their

intracellular distribution. Biomaterials. 2008 Nov;29(32):4333-40. doi:

10.1016/j.biomaterials.2008.07.040. Epub 2008 Aug 15. PubMed PMID: 18708250.

716: Brock Thomas J, Tingsanchali JH, Rosales AM, Creecy CM, McGinity JW, Peppas

NA. Dynamics of Poly(ethylene glycol)-Tethered, pH Responsive Networks. Polymer

(Guildf). 2007 Aug 10;48(17):5042-5048. PubMed PMID: 18690288; PubMed Central

PMCID: PMC2000848.

717: Filippov S, Hrubý M, Konák C, Macková H, Spírková M, Stepánek P. Novel

pH-responsive nanoparticles. Langmuir. 2008 Sep 2;24(17):9295-301. doi:

10.1021/la801472x. Epub 2008 Aug 8. PubMed PMID: 18686981.

718: Chan AW, Whitney RA, Neufeld RJ. Kinetic controlled synthesis of

pH-responsive network alginate. Biomacromolecules. 2008 Sep;9(9):2536-45. doi:

10.1021/bm800594f. Epub 2008 Jul 31. PubMed PMID: 18666793.

719: Ibekwe VC, Khela MK, Evans DF, Basit AW. A new concept in colonic drug

targeting: a combined pH-responsive and bacterially-triggered drug delivery

technology. Aliment Pharmacol Ther. 2008 Oct 1;28(7):911-6. doi:

10.1111/j.1365-2036.2008.03810.x. Epub 2008 Jul 19. PubMed PMID: 18647282.

720: Mu QS, Zhao XB, Lu JR, Armes SP, Lewis AL, Thomas RK. pH-responsive

nanoaggregation of diblock phosphorylcholine copolymers. J Phys Chem B. 2008 Aug

14;112(32):9652-9. doi: 10.1021/jp710365u. Epub 2008 Jul 19. PubMed PMID:

18637682.

721: Kashiwada A, Matsuda K, Mizuno T, Tanaka T. Construction of a pH-responsive

artificial membrane fusion system by using designed coiled-coil polypeptides.

Chemistry. 2008;14(24):7343-50. doi: 10.1002/chem.200701726. PubMed PMID:

18626873.

722: Li G, Liu G, Kang ET, Neoh KG, Yang X. pH-Responsive hollow polymeric

microspheres and concentric hollow silica microspheres from silica-polymer

core-shell microspheres. Langmuir. 2008 Aug 19;24(16):9050-5. doi:

10.1021/la8010579. Epub 2008 Jul 8. PubMed PMID: 18605745.

723: Ali MM, Woods M, Caravan P, Opina AC, Spiller M, Fettinger JC, Sherry AD.

Synthesis and relaxometric studies of a dendrimer-based pH-responsive MRI

contrast agent. Chemistry. 2008;14(24):7250-8. doi: 10.1002/chem.200800402.

PubMed PMID: 18601236; PubMed Central PMCID: PMC2758099.

724: Dunér G, Anderson H, Myrskog A, Hedlund M, Aastrup T, Ramström O.

Surface-confined photopolymerization of pH-responsive acrylamide/acrylate brushes

on polymer thin films. Langmuir. 2008 Jul 15;24(14):7559-64. doi:

10.1021/la800700h. Epub 2008 Jun 19. PubMed PMID: 18563922.

725: Basnar B, Schartner S, Austerer M, Andrews AM, Roch T, Schrenk W, Strasser

G. Reversible switching of quantum cascade laser-modes using a pH-responsive

polymeric cladding as transducer. Opt Express. 2008 Jun 9;16(12):8557-69. PubMed

PMID: 18545569.

726: Zhao Y, Yokoi H, Tanaka M, Kinoshita T, Tan T. Self-assembled pH-responsive

hydrogels composed of the RATEA16 peptide. Biomacromolecules. 2008

Jun;9(6):1511-8. doi: 10.1021/bm701143g. Epub 2008 May 23. PubMed PMID: 18498190.

727: Ibekwe VC, Fadda HM, McConnell EL, Khela MK, Evans DF, Basit AW. Interplay

between intestinal pH, transit time and feed status on the in vivo performance of

pH responsive ileo-colonic release systems. Pharm Res. 2008 Aug;25(8):1828-35.

doi: 10.1007/s11095-008-9580-9. Epub 2008 May 9. PubMed PMID: 18465212.

728: Pérez-Mayoral E, Negri V, Soler-Padrós J, Cerdán S, Ballesteros P. Chemistry

of paramagnetic and diamagnetic contrast agents for Magnetic Resonance Imaging

and Spectroscopy pH responsive contrast agents. Eur J Radiol. 2008

Sep;67(3):453-8. doi: 10.1016/j.ejrad.2008.02.048. Epub 2008 May 1. Review.

PubMed PMID: 18455343.

729: Renner L, Osaki T, Chiantia S, Schwille P, Pompe T, Werner C. Supported

lipid bilayers on spacious and pH-responsive polymer cushions with varied

hydrophilicity. J Phys Chem B. 2008 May 22;112(20):6373-8. doi:

10.1021/jp711479f. Epub 2008 Apr 22. PubMed PMID: 18426235.

730: Casali M, Banta S, Zambonelli C, Megeed Z, Yarmush ML. Site-directed

mutagenesis of the hinge peptide from the hemagglutinin protein: enhancement of

the pH-responsive conformational change. Protein Eng Des Sel. 2008

Jun;21(6):395-404. doi: 10.1093/protein/gzn018. Epub 2008 Apr 14. PubMed PMID:

18411225.

731: Shen Y, Tang H, Radosz M, Van Kirk E, Murdoch WJ. pH-responsive

nanoparticles for cancer drug delivery. Methods Mol Biol. 2008;437:183-216. doi:

10.1007/978-1-59745-210-6_10. Review. PubMed PMID: 18369970.

732: Tan JP, Zeng AQ, Chang CC, Tam KC. Release kinetics of procaine

hydrochloride (PrHy) from pH-responsive nanogels: theory and experiments. Int J

Pharm. 2008 Jun 5;357(1-2):305-13. doi: 10.1016/j.ijpharm.2008.01.058. Epub 2008

Feb 8. PubMed PMID: 18358651.

733: Pinprayoon O, Groves R, Saunders BR. A study of poly(butadiene/methacrylic

acid) dispersions: from pH-responsive behaviour to the effects of added Ca2+. J

Colloid Interface Sci. 2008 May 15;321(2):315-22. doi:

10.1016/j.jcis.2008.02.037. Epub 2008 Feb 29. PubMed PMID: 18355833.

734: Shome A, Debnath S, Das PK. Head group modulated pH-responsive hydrogel of

amino acid-based amphiphiles: entrapment and release of cytochrome c and vitamin

B12. Langmuir. 2008 Apr 15;24(8):4280-8. doi: 10.1021/la704024p. Epub 2008 Mar 7.

PubMed PMID: 18324868.

735: Zhang Q, Xia F, Sun T, Song W, Zhao T, Liu M, Jiang L. Wettability switching

between high hydrophilicity at low pH and high hydrophobicity at high pH on

surface based on pH-responsive polymer. Chem Commun (Camb). 2008 Mar

14;(10):1199-201. doi: 10.1039/b716681h. Epub 2008 Jan 16. PubMed PMID: 18309416.

736: Dalmont H, Pinprayoon O, Saunders BR. Study of pH-responsive microgels

containing methacrylic acid: effects of particle composition and added calcium.

Langmuir. 2008 Mar 18;24(6):2834-40. doi: 10.1021/la703597a. Epub 2008 Feb 22.

PubMed PMID: 18290684.

737: Meyer M, Philipp A, Oskuee R, Schmidt C, Wagner E. Breathing life into

polycations: functionalization with pH-responsive endosomolytic peptides and

polyethylene glycol enables siRNA delivery. J Am Chem Soc. 2008 Mar

19;130(11):3272-3. doi: 10.1021/ja710344v. Epub 2008 Feb 21. PubMed PMID:

18288843.

738: Angelos S, Yang YW, Patel K, Stoddart JF, Zink JI. pH-responsive

supramolecular nanovalves based on cucurbit[6]uril pseudorotaxanes. Angew Chem

Int Ed Engl. 2008;47(12):2222-6. doi: 10.1002/anie.200705211. PubMed PMID:

18275057.

739: Chiu HC, Lin YW, Huang YF, Chuang CK, Chern CS. Polymer vesicles containing

small vesicles within interior aqueous compartments and pH-responsive

transmembrane channels. Angew Chem Int Ed Engl. 2008;47(10):1875-8. doi:

10.1002/anie.200704078. PubMed PMID: 18176922.

740: Lee SM, Chen H, Dettmer CM, O'Halloran TV, Nguyen ST. Polymer-caged

lipsomes: a pH-responsive delivery system with high stability. J Am Chem Soc.

2007 Dec 12;129(49):15096-7. Epub 2007 Nov 14. PubMed PMID: 17999499.

741: Tan JP, Goh CH, Tam KC. Comparative drug release studies of two cationic

drugs from pH-responsive nanogels. Eur J Pharm Sci. 2007 Dec;32(4-5):340-8. Epub

2007 Sep 7. PubMed PMID: 17950583.

742: Zhang X, Li J, Li W, Zhang A. Synthesis and characterization of thermo- and

pH-responsive double-hydrophilic diblock copolypeptides. Biomacromolecules. 2007

Nov;8(11):3557-67. Epub 2007 Oct 5. PubMed PMID: 17918895.

743: Horkay F, Han MH, Han IS, Bang IS, Magda JJ. Separation of the effects of pH

and polymer concentration on the swelling pressure and elastic modulus of a

pH-responsive hydrogel. Polymer (Guildf). 2006 Oct 4;47(21):7335-7338. PubMed

PMID: 17917687; PubMed Central PMCID: PMC1827201.

744: Ko J, Park K, Kim YS, Kim MS, Han JK, Kim K, Park RW, Kim IS, Song HK, Lee

DS, Kwon IC. Tumoral acidic extracellular pH targeting of pH-responsive

MPEG-poly(beta-amino ester) block copolymer micelles for cancer therapy. J

Control Release. 2007 Nov 6;123(2):109-15. Epub 2007 Aug 8. PubMed PMID:

17894942.

745: Hu Y, Litwin T, Nagaraja AR, Kwong B, Katz J, Watson N, Irvine DJ. Cytosolic

delivery of membrane-impermeable molecules in dendritic cells using pH-responsive

core-shell nanoparticles. Nano Lett. 2007 Oct;7(10):3056-64. Epub 2007 Sep 21.

PubMed PMID: 17887715.

746: You BJ, Choquer M, Chung KR. The Colletotrichum acutatum gene encoding a

putative pH-responsive transcription regulator is a key virulence determinant

during fungal pathogenesis on citrus. Mol Plant Microbe Interact. 2007

Sep;20(9):1149-60. PubMed PMID: 17849717.

747: Lee ES, Oh KT, Kim D, Youn YS, Bae YH. Tumor pH-responsive flower-like

micelles of poly(L-lactic acid)-b-poly(ethylene glycol)-b-poly(L-histidine). J

Control Release. 2007 Oct 18;123(1):19-26. Epub 2007 Aug 16. PubMed PMID:

17826863; PubMed Central PMCID: PMC2196406.

748: Tan BH, Tam KC. Review on the dynamics and micro-structure of pH-responsive

nano-colloidal systems. Adv Colloid Interface Sci. 2008 Jan 15;136(1-2):25-44.

Epub 2007 Jul 13. Review. PubMed PMID: 17707760.

749: Namkung S, Chu CC. Partially biodegradable temperature- and pH-responsive

poly(N-isopropylacrylamide)/dextran-maleic acid hydrogels: formulation and

controlled drug delivery of doxorubicin. J Biomater Sci Polym Ed.

2007;18(7):901-24. PubMed PMID: 17688747.

750: Xu S, Luo Y, Haag R. Water-soluble pH-responsive dendritic core-shell

nanocarriers for polar dyes based on poly(ethylene imine). Macromol Biosci. 2007

Aug 7;7(8):968-74. PubMed PMID: 17665413.

751: Binks BP, Murakami R, Armes SP, Fujii S, Schmid A. pH-responsive aqueous

foams stabilized by ionizable latex particles. Langmuir. 2007 Aug

14;23(17):8691-4. Epub 2007 Jul 21. PubMed PMID: 17658859.

752: Sakai K, Smith EG, Webber GB, Baker M, Wanless EJ, Bütün V, Armes SP, Biggs

S. pH-responsive behavior of selectively quaternized diblock copolymers adsorbed

at the silica/aqueous solution interface. J Colloid Interface Sci. 2007 Oct

15;314(2):381-8. Epub 2007 Jun 16. PubMed PMID: 17610891.

753: Hilderbrand SA, Weissleder R. Optimized pH-responsive cyanine fluorochromes

for detection of acidic environments. Chem Commun (Camb). 2007 Jul

14;(26):2747-9. Epub 2007 Apr 20. PubMed PMID: 17594041.

754: Xiong MP, Bae Y, Fukushima S, Forrest ML, Nishiyama N, Kataoka K, Kwon GS.

pH-responsive Multi-PEGylated dual cationic nanoparticles enable charge

modulations for safe gene delivery. ChemMedChem. 2007 Sep;2(9):1321-7. PubMed

PMID: 17579918.

755: Wang D, Chen L. Temperature and pH-responsive single-walled carbon nanotube

dispersions. Nano Lett. 2007 Jun;7(6):1480-4. Epub 2007 May 8. PubMed PMID:

17488048.

756: Zhou J, Wang L, Yang Q, Liu Q, Yu H, Zhao Z. Novel thermoresponsive and

pH-responsive aggregates from self-assembly of triblock copolymer

PSMA-b-PNIPAAm-b-PSMA. J Phys Chem B. 2007 May 24;111(20):5573-80. Epub 2007 May

2. PubMed PMID: 17472366.

757: Sanjuan S, Perrin P, Pantoustier N, Tran Y. Synthesis and swelling behavior

of pH-responsive polybase brushes. Langmuir. 2007 May 8;23(10):5769-78. Epub 2007

Apr 11. PubMed PMID: 17425342.

758: Palioura D, Armes SP, Anastasiadis SH, Vamvakaki M. Metal nanocrystals

incorporated within pH-responsive microgel particles. Langmuir. 2007 May

8;23(10):5761-8. Epub 2007 Apr 5. PubMed PMID: 17408293.

759: Hu L, Chu LY, Yang M, Wang HD, Hui Niu C. Preparation and characterization

of novel cationic pH-responsive poly(N,N'-dimethylamino ethyl methacrylate)

microgels. J Colloid Interface Sci. 2007 Jul 1;311(1):110-7. Epub 2007 Feb 24.

PubMed PMID: 17397857.

760: Lan Q, Liu C, Yang F, Liu S, Xu J, Sun D. Synthesis of bilayer oleic

acid-coated Fe3O4 nanoparticles and their application in pH-responsive Pickering

emulsions. J Colloid Interface Sci. 2007 Jun 1;310(1):260-9. Epub 2007 Feb 2.

PubMed PMID: 17382339.

761: Pflock M, Müller S, Beier D. The CrdRS (HP1365-HP1364) two-component system

is not involved in ph-responsive gene regulation in the Helicobacter pylori

Strains 26695 and G27. Curr Microbiol. 2007 Apr;54(4):320-4. Epub 2007 Mar 12.

PubMed PMID: 17375361.

762: Karanikolopoulos N, Pitsikalis M, Hadjichristidis N, Georgikopoulou K,

Calogeropoulou T, Dunlap JR. pH-responsive aggregates from double hydrophilic

block copolymers carrying zwitterionic groups. Encapsulation of antiparasitic

compounds for the treatment of leishmaniasis. Langmuir. 2007 Apr

10;23(8):4214-24. Epub 2007 Mar 16. PubMed PMID: 17362035.

763: Dong W, Zhou Y, Yan D, Li H, Liu Y. pH-responsive self-assembly of

carboxyl-terminated hyperbranched polymers. Phys Chem Chem Phys. 2007 Mar

14;9(10):1255-62. Epub 2007 Jan 23. PubMed PMID: 17325772.

764: Tan BH, Ravi P, Tan LN, Tam KC. Synthesis and aqueous solution properties of

sterically stabilized pH-responsive polyampholyte microgels. J Colloid Interface

Sci. 2007 May 15;309(2):453-63. Epub 2007 Feb 16. PubMed PMID: 17307196.

765: Karppi J, Akerman S, Akerman K, Sundell A, Nyyssönen K, Penttilä I.

Adsorption of drugs onto a pH responsive poly(N,N-dimethyl aminoethyl

methacrylate) grafted anion-exchange membrane in vitro. Int J Pharm. 2007 Jun

29;338(1-2):7-14. Epub 2007 Jan 19. PubMed PMID: 17289313.

766: Tan JP, Tam KC. Application of drug selective electrode in the drug release

study of pH-responsive microgels. J Control Release. 2007 Mar 12;118(1):87-94.

Epub 2006 Nov 25. PubMed PMID: 17250922.

767: Park C, Oh K, Lee SC, Kim C. Controlled release of guest molecules from

mesoporous silica particles based on a pH-responsive polypseudorotaxane motif.

Angew Chem Int Ed Engl. 2007;46(9):1455-7. PubMed PMID: 17221893.

768: Morgan SE, Jones P, Lamont AS, Heidenreich A, McCormick CL. Layer-by-layer

assembly of pH-responsive, compositionally controlled (co)polyelectrolytes

synthesized via RAFT. Langmuir. 2007 Jan 2;23(1):230-40. PubMed PMID: 17190509.

769: Garcia A, Marquez M, Cai T, Rosario R, Hu Z, Gust D, Hayes M, Vail SA, Park

CD. Photo-, thermally, and pH-responsive microgels. Langmuir. 2007 Jan

2;23(1):224-9. PubMed PMID: 17190508.

770: Wang F, Bazan GC. Aggregation-mediated optical properties of pH-responsive

anionic conjugated polyelectrolytes. J Am Chem Soc. 2006 Dec 13;128(49):15786-92.

PubMed PMID: 17147388.

771: Schmaljohann D. Thermo- and pH-responsive polymers in drug delivery. Adv

Drug Deliv Rev. 2006 Dec 30;58(15):1655-70. Epub 2006 Oct 18. Review. PubMed

PMID: 17125884.

772: Satturwar P, Eddine MN, Ravenelle F, Leroux JC. pH-responsive polymeric

micelles of poly(ethylene glycol)-b-poly(alkyl(meth)acrylate-co-methacrylic

acid): influence of the copolymer composition on self-assembling properties and

release of candesartan cilexetil. Eur J Pharm Biopharm. 2007 Mar;65(3):379-87.

Epub 2006 Oct 7. PubMed PMID: 17123802.

773: Determan MD, Cox JP, Mallapragada SK. Drug release from pH-responsive

thermogelling pentablock copolymers. J Biomed Mater Res A. 2007 May;81(2):326-33.

PubMed PMID: 17120218.

774: Wei H, Zhang XZ, Cheng H, Chen WQ, Cheng SX, Zhuo RX. Self-assembled thermo-

and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide)

for drug delivery. J Control Release. 2006 Dec 1;116(3):266-74. Epub 2006 Sep 1.

PubMed PMID: 17097179.

775: Xu S, Krämer M, Haag R. pH-Responsive dendritic core-shell architectures as

amphiphilic nanocarriers for polar drugs. J Drug Target. 2006 Jul;14(6):367-74.

PubMed PMID: 17092837.

776: Saito H, Taguchi T, Aoki H, Murabayashi S, Mitamura Y, Tanaka J, Tateishi T.

pH-responsive swelling behavior of collagen gels prepared by novel crosslinkers

based on naturally derived di- or tricarboxylic acids. Acta Biomater. 2007

Jan;3(1):89-94. Epub 2006 Oct 20. PubMed PMID: 17055791.

777: Zheng P, Jiang X, Zhang X, Zhang W, Shi L. Formation of gold@polymer

core-shell particles and gold particle clusters on a template of thermoresponsive

and pH-responsive coordination triblock copolymer. Langmuir. 2006 Oct

24;22(22):9393-6. PubMed PMID: 17042559.

778: Varga I, Szalai I, Mészaros R, Gilanyi T. Pulsating pH-responsive nanogels.

J Phys Chem B. 2006 Oct 19;110(41):20297-301. PubMed PMID: 17034210.

779: Sakai K, Smith EG, Webber GB, Baker M, Wanless EJ, Bütün V, Armes SP, Biggs

S. Characterizing the pH-responsive behavior of thin films of diblock copolymer

micelles at the silica/aqueous solution interface. Langmuir. 2006 Sep

26;22(20):8435-42. PubMed PMID: 16981760.

780: Shahalom S, Tong T, Emmett S, Saunders BR. Poly(DEAEMa-co-PEGMa): a new

pH-responsive comb copolymer stabilizer for emulsions and dispersions. Langmuir.

2006 Sep 26;22(20):8311-7. PubMed PMID: 16981742.

781: Alexander C. Temperature- and pH-responsive smart polymers for gene

delivery. Expert Opin Drug Deliv. 2006 Sep;3(5):573-81. Review. PubMed PMID:

16948554.

782: Meyer M, Wagner E. pH-responsive shielding of non-viral gene vectors. Expert

Opin Drug Deliv. 2006 Sep;3(5):563-71. Review. PubMed PMID: 16948553.

783: Aime S, Fedeli F, Sanino A, Terreno E. A R2/R1 ratiometric procedure for a

concentration-independent, pH-responsive, Gd(III)-based MRI agent. J Am Chem Soc.

2006 Sep 6;128(35):11326-7. PubMed PMID: 16939235.

784: Sakai K, Smith EG, Webber GB, Wanless EJ, Bütün V, Armes SP, Biggs S.

Effects of copolymer concentration and chain length on the pH-responsive behavior

of diblock copolymer micellar films. J Colloid Interface Sci. 2006 Nov

15;303(2):372-9. Epub 2006 Aug 2. PubMed PMID: 16930613.

785: Dong J, Qian W. Dye/gelled colloidal photonic crystal composites and their

reversible pH-responsive optical behaviors. J Phys Chem B. 2006 Aug

31;110(34):16823-6. PubMed PMID: 16927969.

786: Ibekwe VC, Liu F, Fadda HM, Khela MK, Evans DF, Parsons GE, Basit AW. An

investigation into the in vivo performance variability of pH responsive polymers

for ileo-colonic drug delivery using gamma scintigraphy in humans. J Pharm Sci.

2006 Dec;95(12):2760-6. PubMed PMID: 16917845.

787: Henry SM, El-Sayed ME, Pirie CM, Hoffman AS, Stayton PS. pH-responsive

poly(styrene-alt-maleic anhydride) alkylamide copolymers for intracellular drug

delivery. Biomacromolecules. 2006 Aug;7(8):2407-14. PubMed PMID: 16903689.

788: Chécot F, Rodríguez-Hernández J, Gnanou Y, Lecommandoux S. pH-responsive

micelles and vesicles nanocapsules based on polypeptide diblock copolymers.

Biomol Eng. 2007 Feb;24(1):81-5. Epub 2006 Jun 3. PubMed PMID: 16870504.

789: Sakai K, Smith EG, Webber GB, Schatz C, Wanless EJ, Bütün V, Armes SP, Biggs

S. pH-responsive diblock copolymer micelles at the silica/aqueous solution

interface: Adsorption kinetics and equilibrium studies. J Phys Chem B. 2006 Aug

3;110(30):14744-53. PubMed PMID: 16869582.

790: Sawant RM, Hurley JP, Salmaso S, Kale A, Tolcheva E, Levchenko TS, Torchilin

VP. "SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical

nanocarriers. Bioconjug Chem. 2006 Jul-Aug;17(4):943-9. PubMed PMID: 16848401;

PubMed Central PMCID: PMC2538444.

791: Ooya T, Inoue D, Choi HS, Kobayashi Y, Loethen S, Thompson DH, Ko YH, Kim K,

Yui N. pH-responsive movement of cucurbit[7]uril in a diblock polypseudorotaxane

containing dimethyl beta-cyclodextrin and cucurbit[7]uril. Org Lett. 2006 Jul

20;8(15):3159-62. PubMed PMID: 16836355.

792: Zimenkov Y, Dublin SN, Ni R, Tu RS, Breedveld V, Apkarian RP, Conticello VP.

Rational design of a reversible pH-responsive switch for peptide self-assembly. J

Am Chem Soc. 2006 May 31;128(21):6770-1. PubMed PMID: 16719440.

793: Oishi M, Kataoka K, Nagasaki Y. pH-responsive three-layered PEGylated

polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable

and endosome-disruptive nonviral gene vector. Bioconjug Chem. 2006

May-Jun;17(3):677-88. PubMed PMID: 16704205.

794: Madihally SV, Pantelogianis A, Toner M. Antiproteolytic action of orally

delivered insulin using pH-responsive hydrogels in a rat burn model. J Surg Res.

2006 Sep;135(1):187-94. Epub 2006 Apr 17. PubMed PMID: 16616764.

795: Ono SS, Decher G. Preparation of ultrathin self-standing polyelectrolyte

multilayer membranes at physiological conditions using pH-responsive film

segments as sacrificial layers. Nano Lett. 2006 Apr;6(4):592-8. PubMed PMID:

16608250.

796: Jiang Y, Wang Z, Xu H, Chen H, Zhang X, Smet M, Dehaen W, Hirano Y, Ozaki Y.

Investigation into pH-responsive self-assembled monolayers of acylated

anthranilate-terminated alkanethiol on a gold surface. Langmuir. 2006 Apr

11;22(8):3715-20. PubMed PMID: 16584247.

797: Dupin D, Fujii S, Armes SP, Reeve P, Baxter SM. Efficient synthesis of

sterically stabilized pH-responsive microgels of controllable particle diameter

by emulsion polymerization. Langmuir. 2006 Mar 28;22(7):3381-7. PubMed PMID:

16548605.

798: Xu P, Van Kirk EA, Murdoch WJ, Zhan Y, Isaak DD, Radosz M, Shen Y.

Anticancer efficacies of cisplatin-releasing pH-responsive nanoparticles.

Biomacromolecules. 2006 Mar;7(3):829-35. PubMed PMID: 16529420; PubMed Central

PMCID: PMC2533846.

799: Giacomelli C, Le Men L, Borsali R, Lai-Kee-Him J, Brisson A, Armes SP, Lewis

AL. Phosphorylcholine-based pH-responsive diblock copolymer micelles as drug

delivery vehicles: light scattering, electron microscopy, and fluorescence

experiments. Biomacromolecules. 2006 Mar;7(3):817-28. PubMed PMID: 16529419.

800: Sui Z, Schlenoff JB. Phase separations in pH-responsive polyelectrolyte

multilayers: charge extrusion versus charge expulsion. Langmuir. 2004 Jul

6;20(14):6026-31. PubMed PMID: 16459626.

801: Higashi N, Shosu T, Koga T, Niwa M, Tanigawa T. pH-responsive,

self-assembling nanoparticle from a fullerene-tagged poly(L-glutamic acid) and

its superoxide dismutase mimetic property. J Colloid Interface Sci. 2006 Jun

1;298(1):118-23. Epub 2006 Jan 10. PubMed PMID: 16412454.

802: Sethuraman VA, Na K, Bae YH. pH-responsive sulfonamide/PEI system for tumor

specific gene delivery: an in vitro study. Biomacromolecules. 2006

Jan;7(1):64-70. PubMed PMID: 16398499.

803: Ibekwe VC, Fadda HM, Parsons GE, Basit AW. A comparative in vitro assessment

of the drug release performance of pH-responsive polymers for ileo-colonic

delivery. Int J Pharm. 2006 Feb 3;308(1-2):52-60. Epub 2005 Dec 13. PubMed PMID:

16356670.

804: Kwon YJ, James E, Shastri N, Fréchet JM. In vivo targeting of dendritic

cells for activation of cellular immunity using vaccine carriers based on

pH-responsive microparticles. Proc Natl Acad Sci U S A. 2005 Dec

20;102(51):18264-8. Epub 2005 Dec 12. PubMed PMID: 16344458; PubMed Central

PMCID: PMC1317987.

805: Liu YY, Fan XD, Wei BR, Si QF, Chen WX, Sun L. pH-responsive amphiphilic

hydrogel networks with IPN structure: a strategy for controlled drug release. Int

J Pharm. 2006 Feb 3;308(1-2):205-9. PubMed PMID: 16321489.

806: O'Hayre M, Taylor L, Andratsch M, Feifel E, Gstraunthaler G, Curthoys NP.

Effects of constitutively active and dominant negative MAPK kinase (MKK) 3 and

MKK6 on the pH-responsive increase in phosphoenolpyruvate carboxykinase mRNA. J

Biol Chem. 2006 Feb 3;281(5):2982-8. Epub 2005 Nov 30. PubMed PMID: 16319064.

807: Bai D, Habersberger BM, Jennings GK. pH-responsive copolymer films by

surface-catalyzed growth. J Am Chem Soc. 2005 Nov 30;127(47):16486-93. PubMed

PMID: 16305235.

808: Duan H, Kuang M, Zhang G, Wang D, Kurth DG, Möhwald H. pH-responsive

capsules derived from nanocrystal templating. Langmuir. 2005 Nov

22;21(24):11495-9. PubMed PMID: 16285832.

809: Hayashi M, Fukuzawa T, Sorimachi H, Maeda T. Constitutive activation of the

pH-responsive Rim101 pathway in yeast mutants defective in late steps of the

MVB/ESCRT pathway. Mol Cell Biol. 2005 Nov;25(21):9478-90. PubMed PMID: 16227598;

PubMed Central PMCID: PMC1265799.

810: Schroeder JM, Ibrahim H, Taylor L, Curthoys NP. Role of deadenylation and

AUF1 binding in the pH-responsive stabilization of glutaminase mRNA. Am J Physiol

Renal Physiol. 2006 Mar;290(3):F733-40. Epub 2005 Oct 11. PubMed PMID: 16219914.

811: Taira S, Du YZ, Kodaka M. Trap and release of oligonucleotide using

pH-responsive amphoteric particle prepared by interfacial polymerization in W/O

miniemulsion system. Biotechnol Bioeng. 2006 Feb 5;93(2):396-400. PubMed PMID:

16189820.

812: Wang CH, Wang CH, Hsiue GH. Polymeric micelles with a pH-responsive

structure as intracellular drug carriers. J Control Release. 2005 Nov

2;108(1):140-9. Epub 2005 Sep 22. PubMed PMID: 16182401.

813: Yenush L, Merchan S, Holmes J, Serrano R. pH-Responsive, posttranslational

regulation of the Trk1 potassium transporter by the type 1-related Ppz1

phosphatase. Mol Cell Biol. 2005 Oct;25(19):8683-92. PubMed PMID: 16166647;

PubMed Central PMCID: PMC1265754.

814: Du J, Armes SP. pH-responsive vesicles based on a hydrolytically

self-cross-linkable copolymer. J Am Chem Soc. 2005 Sep 21;127(37):12800-1. PubMed

PMID: 16159264.

815: Chen R, Yue Z, Eccleston ME, Williams S, Slater NK. Modulation of cell

membrane disruption by pH-responsive pseudo-peptides through grafting with

hydrophilic side chains. J Control Release. 2005 Nov 2;108(1):63-72. Epub 2005

Sep 2. PubMed PMID: 16139914.

816: Sajeesh S, Sharma CP. Novel pH responsive polymethacrylic

acid-chitosan-polyethylene glycol nanoparticles for oral peptide delivery. J

Biomed Mater Res B Appl Biomater. 2006 Feb;76(2):298-305. PubMed PMID: 16130147.

817: Christman KL, Maynard HD. Protein micropatterns using a pH-responsive

polymer and light. Langmuir. 2005 Aug 30;21(18):8389-93. PubMed PMID: 16114947.

818: Houillot L, Nicolas J, Save M, Charleux B, Li Y, Armes SP. Miniemulsion

polymerization of styrene using a pH-responsive cationic diblock macromonomer and

its nonreactive diblock copolymer counterpart as stabilizers. Langmuir. 2005 Jul

19;21(15):6726-33. PubMed PMID: 16008381.

819: Liu Y, Chen GS, Chen Y, Ding F, Chen J. Cyclodextrins as carriers for

cinchona alkaloids: a pH-responsive selective binding system. Org Biomol Chem.

2005 Jul 21;3(14):2519-23. Epub 2005 Jun 22. PubMed PMID: 15999183.

820: El-Sayed ME, Hoffman AS, Stayton PS. Rational design of composition and

activity correlations for pH-responsive and glutathione-reactive polymer

therapeutics. J Control Release. 2005 May 18;104(2):417-27. PubMed PMID:

15984055.

821: Castelletto V, Hamley IW, Ma Y, Bories-Azeau X, Armes SP, Lewis AL.

Microstructure and physical properties of a pH-responsive gel based on a novel

biocompatible ABA-type triblock copolymer. Langmuir. 2004 May 11;20(10):4306-9.

PubMed PMID: 15969434.

822: Yue Z, Eccleston ME, Slater NK. Modulation of the pH-responsive properties

of poly(L-lysine iso-phthalamide) grafted with a poly(ethylene glycol) analogue.

Biomaterials. 2005 Nov;26(32):6357-66. PubMed PMID: 15913772.

823: Oms O, van der Lee A, Le Bideau J, Leclercq D. Redox-active pH-responsive

molecules: ferrocenylphosphonic acid, ferrocenylmethylphosphonic acid and

1,1'-ferrocenylbisphosphonic acid. Structural determination of FcPO3Na2.5H2O.

Dalton Trans. 2005 Jun 7;(11):1903-9. Epub 2005 May 3. PubMed PMID: 15909036.

824: Fujii S, Cai Y, Weaver JV, Armes SP. Syntheses of shell cross-linked

micelles using acidic ABC triblock copolymers and their application as

pH-responsive particulate emulsifiers. J Am Chem Soc. 2005 May 25;127(20):7304-5.

PubMed PMID: 15898766.

825: Fang N, Tan WJ, Leong KW, Mao HQ, Chan V. pH responsive adhesion of

phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene

terephthalate) surface. Colloids Surf B Biointerfaces. 2005 May

25;42(3-4):245-52. PubMed PMID: 15893225.

826: Stevens MM, Allen S, Davies MC, Roberts CJ, Sakata JK, Tendler SJ, Tirrell

DA, Williams PM. Molecular level investigations of the inter- and intramolecular

interactions of pH-responsive artificial triblock proteins. Biomacromolecules.

2005 May-Jun;6(3):1266-71. PubMed PMID: 15877341.

827: de Las Heras Alarcón C, Twaites B, Cunliffe D, Smith JR, Alexander C.

Grafted thermo- and pH responsive co-polymers: surface-properties and bacterial

adsorption. Int J Pharm. 2005 May 13;295(1-2):77-91. PubMed PMID: 15847993.

828: Gillies ER, Fréchet JM. pH-Responsive copolymer assemblies for controlled

release of doxorubicin. Bioconjug Chem. 2005 Mar-Apr;16(2):361-8. PubMed PMID:

15769090.

829: Jiang Y, Wang Z, Yu X, Shi F, Xu H, Zhang X, Smet M, Dehaen W.

Self-assembled monolayers of dendron thiols for electrodeposition of gold

nanostructures: toward fabrication of superhydrophobic/superhydrophilic surfaces

and pH-responsive surfaces. Langmuir. 2005 Mar 1;21(5):1986-90. PubMed PMID:

15723499.

830: Rodríguez-Hernández J, Lecommandoux S. Reversible inside-out micellization

of pH-responsive and water-soluble vesicles based on polypeptide diblock

copolymers. J Am Chem Soc. 2005 Feb 23;127(7):2026-7. PubMed PMID: 15713063.

831: Zhang Y, Jiang M, Zhao J, Wang Z, Dou H, Chen D. pH-responsive core-shell

particles and hollow spheres attained by macromolecular self-assembly. Langmuir.

2005 Feb 15;21(4):1531-8. PubMed PMID: 15697304.

832: Bignell E, Negrete-Urtasun S, Calcagno AM, Haynes K, Arst HN Jr, Rogers T.

The Aspergillus pH-responsive transcription factor PacC regulates virulence. Mol

Microbiol. 2005 Feb;55(4):1072-84. PubMed PMID: 15686555.

833: Tóth E, Bolskar RD, Borel A, González G, Helm L, Merbach AE, Sitharaman B,

Wilson LJ. Water-soluble gadofullerenes: toward high-relaxivity, pH-responsive

MRI contrast agents. J Am Chem Soc. 2005 Jan 19;127(2):799-805. PubMed PMID:

15643906.

834: Zhou SL, Matsumoto S, Tian HD, Yamane H, Ojida A, Kiyonaka S, Hamachi I.

pH-Responsive shrinkage/swelling of a supramolecular hydrogel composed of two

small amphiphilic molecules. Chemistry. 2005 Feb 4;11(4):1130-6. PubMed PMID:

15619729.

835: Traitel T, Kost J. pH-responsive hydrogels: swelling model. Adv Exp Med

Biol. 2004;553:29-43. PubMed PMID: 15503445.

836: Veron L, Ganée A, Charreyre MT, Pichot C, Delair T. New hydrolyzable

pH-responsive cationic polymers for gene delivery: a preliminary study. Macromol

Biosci. 2004 Apr 19;4(4):431-44. PubMed PMID: 15468235.

837: Amalvy JI, Wanless EJ, Li Y, Michailidou V, Armes SP, Duccini Y. Synthesis

and characterization of novel pH-responsive microgels based on tertiary amine

methacrylates. Langmuir. 2004 Oct 12;20(21):8992-9. PubMed PMID: 15461478.

838: Wang C, Tam KC, Tan CB. Binding of dodecyltrimethylammonium bromide to

pH-responsive nanocolloids containing cross-linked methacrylic acid-ethyl

acrylate copolymers. Langmuir. 2004 Sep 14;20(19):7933-9. PubMed PMID: 15350055.

839: Read ES, Fujii S, Amalvy JI, Randall DP, Armes SP. Effect of varying the oil

phase on the behavior of pH-responsive latex-based emulsifiers: demulsification

versus transitional phase inversion. Langmuir. 2004 Aug 31;20(18):7422-9. PubMed

PMID: 15323485.

840: Déjugnat C, Sukhorukov GB. pH-responsive properties of hollow

polyelectrolyte microcapsules templated on various cores. Langmuir. 2004 Aug

17;20(17):7265-9. PubMed PMID: 15301514.

841: Woods M, Kiefer GE, Bott S, Castillo-Muzquiz A, Eshelbrenner C, Michaudet L,

McMillan K, Mudigunda SD, Ogrin D, Tircsó G, Zhang S, Zhao P, Sherry AD.

Synthesis, relaxometric and photophysical properties of a new pH-responsive MRI

contrast agent: the effect of other ligating groups on dissociation of a

p-nitrophenolic pendant arm. J Am Chem Soc. 2004 Aug 4;126(30):9248-56. PubMed

PMID: 15281814; PubMed Central PMCID: PMC2741012.

842: Plunkett KN, Moore JS. Patterned dual pH-responsive core-shell hydrogels

with controllable swelling kinetics and volumes. Langmuir. 2004 Aug

3;20(16):6535-7. PubMed PMID: 15274549.

843: Løkling KE, Fossheim SL, Klaveness J, Skurtveit R. Biodistribution of

pH-responsive liposomes for MRI and a novel approach to improve the

pH-responsiveness. J Control Release. 2004 Jul 23;98(1):87-95. PubMed PMID:

15245892.

844: Twaites BR, de las Heras Alarcón C, Cunliffe D, Lavigne M, Pennadam S, Smith

JR, Górecki DC, Alexander C. Thermo and pH responsive polymers as gene delivery

vectors: effect of polymer architecture on DNA complexation in vitro. J Control

Release. 2004 Jul 7;97(3):551-66. PubMed PMID: 15212886.

845: Zhang K, Wu XY. Temperature and pH-responsive polymeric composite membranes

for controlled delivery of proteins and peptides. Biomaterials. 2004

Oct;25(22):5281-91. PubMed PMID: 15110479.

846: Løkling KE, Skurtveit R, Dyrstad K, Klaveness J, Fossheim SL. Tuning the MR

properties of blood-stable pH-responsive paramagnetic liposomes. Int J Pharm.

2004 Apr 15;274(1-2):75-83. Erratum in: Int J Pharm. 2004 Jul 8;278(2):477.

PubMed PMID: 15072784.

847: Li W, Nicol F, Szoka FC Jr. GALA: a designed synthetic pH-responsive

amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv

Rev. 2004 Apr 23;56(7):967-85. Review. PubMed PMID: 15066755.

848: Waziri SM, Abu-Sharkh BF, Ali SA. Protein partitioning in aqueous two-phase

systems composed of a pH-responsive copolymer and poly(ethylene glycol).

Biotechnol Prog. 2004 Mar-Apr;20(2):526-32. PubMed PMID: 15058998.

849: Sakamoto C, Okada Y, Kanazawa H, Ayano E, Nishimura T, Ando M, Kikuchi A,

Okano T. Temperature- and pH-responsive aminopropyl-silica ion-exchange columns

grafted with copolymers of N-isopropylacrylamide. J Chromatogr A. 2004 Mar

19;1030(1-2):247-53. PubMed PMID: 15043276.

850: Roy I, Gupta MN. pH-responsive polymer-assisted refolding of urea- and

organic solvent-denatured alpha-chymotrypsin. Protein Eng. 2003

Dec;16(12):1153-7. PubMed PMID: 14983099.

851: Bulmus V, Woodward M, Lin L, Murthy N, Stayton P, Hoffman A. A new

pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric

carrier for intracellular delivery of biomolecular drugs. J Control Release. 2003

Dec 5;93(2):105-20. PubMed PMID: 14636717.

852: Burke SE, Barrett CJ. pH-responsive properties of multilayered

poly(L-lysine)/hyaluronic acid surfaces. Biomacromolecules. 2003

Nov-Dec;4(6):1773-83. PubMed PMID: 14606908.

853: Gunnlaugsson T, Leonard JP, Sénéchal K, Harte AJ. pH responsive

Eu(III)-phenanthroline supramolecular conjugate: novel "off-on-off" luminescent

signaling in the physiological pH range. J Am Chem Soc. 2003 Oct

8;125(40):12062-3. PubMed PMID: 14518970.

854: Oishi M, Sasaki S, Nagasaki Y, Kataoka K. pH-responsive oligodeoxynucleotide

(ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate

linkage: preparation and polyion complex micelle formation. Biomacromolecules.

2003 Sep-Oct;4(5):1426-32. PubMed PMID: 12959615.

855: Tachibana Y, Kurisawa M, Uyama H, Kobayashi S. Thermo- and pH-responsive

biodegradable poly(alpha-N-substituted gamma-glutamine)s. Biomacromolecules. 2003

Sep-Oct;4(5):1132-4. PubMed PMID: 12959575.

856: Amalvy JI, Armes SP, Binks BP, Rodrigues JA, Unali GF. Use of

sterically-stabilised polystyrene latex particles as a pH-responsive particulate

emulsifier to prepare surfactant-free oil-in-water emulsions. Chem Commun (Camb).

2003 Aug 7;(15):1826-7. PubMed PMID: 12931986.

857: Kanekiyo Y, Naganawa R, Tao H. pH-responsive molecularly imprinted polymers.

Angew Chem Int Ed Engl. 2003 Jul 7;42(26):3014-6. PubMed PMID: 12851958.

858: Woods M, Sherry AD. Synthesis and luminescence studies of aryl substituted

tetraamide complexes of europium(III): a new approach to pH responsive

luminescent europium probes. Inorg Chem. 2003 Jul 14;42(14):4401-8. PubMed PMID:

12844313.

859: Murthy N, Campbell J, Fausto N, Hoffman AS, Stayton PS. Design and synthesis

of pH-responsive polymeric carriers that target uptake and enhance the

intracellular delivery of oligonucleotides. J Control Release. 2003 May

20;89(3):365-74. PubMed PMID: 12737839.

860: Schroeder JM, Liu W, Curthoys NP. pH-responsive stabilization of glutamate

dehydrogenase mRNA in LLC-PK1-F+ cells. Am J Physiol Renal Physiol. 2003

Aug;285(2):F258-65. Epub 2003 Apr 8. PubMed PMID: 12684230.

861: Murthy N, Campbell J, Fausto N, Hoffman AS, Stayton PS. Bioinspired

pH-responsive polymers for the intracellular delivery of biomolecular drugs.

Bioconjug Chem. 2003 Mar-Apr;14(2):412-9. PubMed PMID: 12643752.

862: Jones JW, Bryant WS, Bosman AW, Janssen RA, Meijer EW, Gibson HW. Crowned

dendrimers: pH-responsive pseudorotaxane formation. J Org Chem. 2003 Mar

21;68(6):2385-9. PubMed PMID: 12636406.

863: Le Garrec D, Taillefer J, Van Lier JE, Lenaerts V, Leroux JC. Optimizing

pH-responsive polymeric micelles for drug delivery in a cancer photodynamic

therapy model. J Drug Target. 2002 Aug;10(5):429-37. PubMed PMID: 12442814.

864: Krämer M, Stumbé JF, Türk H, Krause S, Komp A, Delineau L, Prokhorova S,

Kautz H, Haag R. pH-responsive molecular nanocarriers based on dendritic

core-shell architectures. Angew Chem Int Ed Engl. 2002 Nov 15;41(22):4252-6.

PubMed PMID: 12434354.

865: Lackey CA, Press OW, Hoffman AS, Stayton PS. A biomimetic pH-responsive

polymer directs endosomal release and intracellular delivery of an endocytosed

antibody complex. Bioconjug Chem. 2002 Sep-Oct;13(5):996-1001. PubMed PMID:

12236781.

866: Roux E, Stomp R, Giasson S, Pézolet M, Moreau P, Leroux JC. Steric

stabilization of liposomes by pH-responsive N-isopropylacrylamide copolymer. J

Pharm Sci. 2002 Aug;91(8):1795-802. PubMed PMID: 12115806.

867: Gupta P, Vermani K, Garg S. Hydrogels: from controlled release to

pH-responsive drug delivery. Drug Discov Today. 2002 May 15;7(10):569-79. Review.

PubMed PMID: 12047857.

868: Liu S, Armes SP. Polymeric surfactants for the new millennium: a

pH-responsive, zwitterionic, schizophrenic diblock copolymer. Angew Chem Int Ed

Engl. 2002 Apr 15;41(8):1413-6. PubMed PMID: 19750783.

869: Morishita M, Takayama K. [Application of pH-responsive polymers to oral

dosage forms for insulin]. Nihon Rinsho. 2001 Nov;59(11):2255-60. Review.

Japanese. PubMed PMID: 11712416.

870: Lynn DM, Amiji MM, Langer R. pH-Responsive Polymer Microspheres: Rapid

Release of Encapsulated Material within the Range of Intracellular pH Financial

support was provided by the NSF (Cooperative Agreement No. ECC9843342 to the MIT

Biotechnology Process Engineering Center), the NIH (GM26698), and the Department

of the Army (Cooperative Agreement DAMD 17-99-2-9-001 to the Center for

Innovative Minimally Invasive Therapy). D.M.L. wishes to thank the NIH for a

Postdoctoral Fellowship (NRSA Fellowship No. 1 F32 GM20227-01). Scanning electron

microscopy and confocal microscopy images were acquired by William Fowle at the

Northeastern University Center for Electron Microscopy. Dr. David Putnam, David

Ting, and Tommy Thomas are thanked for helpful discussions. . Angew Chem Int Ed

Engl. 2001 May 4;40(9):1707-1710. PubMed PMID: 11353487.

871: Taillefer J, Brasseur N, van Lier JE, Lenaerts V, Le Garrec D, Leroux JC.

In-vitro and in-vivo evaluation of pH-responsive polymeric micelles in a

photodynamic cancer therapy model. J Pharm Pharmacol. 2001 Feb;53(2):155-66.

PubMed PMID: 11273011.

872: Rathgeb F, Reichl D, Herold M, Mader O, Mutschler T, Gauglitz G. Dyeless

optical detection of ammonia in the gaseous phase using a pH-responsive

polymer--characterization of the sorption process. Fresenius J Anal Chem. 2000

Sep-Oct;368(2-3):192-5. PubMed PMID: 11220578.

873: Eccleston ME, Kuiper M, Gilchrist FM, Slater NK. pH-responsive

pseudo-peptides for cell membrane disruption. J Control Release. 2000 Nov

3;69(2):297-307. PubMed PMID: 11064136.

874: Shantha KL, Harding DR. Preparation and in-vitro evaluation of

poly[N-vinyl-2-pyrrolidone-polyethylene glycol diacrylate]-chitosan

interpolymeric pH-responsive hydrogels for oral drug delivery. Int J Pharm. 2000

Oct 10;207(1-2):65-70. PubMed PMID: 11036231.

875: Zhang Q, Liu L, Zhou H, Wu X, Yao KD. pH-responsive swelling behavior of

collagen complex materials. Artif Cells Blood Substit Immobil Biotechnol. 2000

May;28(3):255-62. PubMed PMID: 10852676.

876: Laterza OF, Curthoys NP. Specificity and functional analysis of the

pH-responsive element within renal glutaminase mRNA. Am J Physiol Renal Physiol.

2000 Jun;278(6):F970-7. PubMed PMID: 10836985.

877: Taillefer J, Jones MC, Brasseur N, van Lier JE, Leroux JC. Preparation and

characterization of pH-responsive polymeric micelles for the delivery of

photosensitizing anticancer drugs. J Pharm Sci. 2000 Jan;89(1):52-62. PubMed

PMID: 10664538.

878: Lowman AM, Peppas NA. Solute transport analysis in pH-responsive, complexing

hydrogels of poly(methacrylic acid-g-ethylene glycol). J Biomater Sci Polym Ed.

1999;10(9):999-1009. PubMed PMID: 10574613.

879: Lowman AM, Morishita M, Kajita M, Nagai T, Peppas NA. Oral delivery of

insulin using pH-responsive complexation gels. J Pharm Sci. 1999 Sep;88(9):933-7.

PubMed PMID: 10479357.

880: Lackey CA, Murthy N, Press OW, Tirrell DA, Hoffman AS, Stayton PS. Hemolytic

activity of pH-responsive polymer-streptavidin bioconjugates. Bioconjug Chem.

1999 May-Jun;10(3):401-5. PubMed PMID: 10346870.

881: Pillay V, Fassihi R. In vitro release modulation from crosslinked pellets

for site-specific drug delivery to the gastrointestinal tract. I. Comparison of

pH-responsive drug release and associated kinetics. J Control Release. 1999 May

20;59(2):229-42. PubMed PMID: 10332057.

882: Negishi M, Hiroki A, Horikoshi Y, Miyajima M, Asano M, Katakai R, Yoshida M.

Swelling and ketoprofen release characteristics of thermo- and pH-responsive

copolymer gels. Drug Dev Ind Pharm. 1999 Apr;25(4):437-44. PubMed PMID: 10194598.

883: Caiolfa VR, Gill D, Parola AH. Probing the active site of adenosine

deaminase by a pH responsive fluorescent competitive inhibitor. Biophys Chem.

1998 Jan 1;70(1):41-56. PubMed PMID: 9474762.

884: Laterza OF, Hansen WR, Taylor L, Curthoys NP. Identification of an

mRNA-binding protein and the specific elements that may mediate the pH-responsive

induction of renal glutaminase mRNA. J Biol Chem. 1997 Sep 5;272(36):22481-8.

PubMed PMID: 9278399.

885: Logan M, Cannon G, McCormick CL. pH responsive microdomain formation in a de

novo polypeptide. Biopolymers. 1997 Apr 15;41(5):521-32. PubMed PMID: 9095675.

886: Sheppard NF Jr, Lesho MJ, Tucker RC, Salehi-Had S. Electrical conductivity

of pH-responsive hydrogels. J Biomater Sci Polym Ed. 1997;8(5):349-62. PubMed

PMID: 9105975.

887: Hansen WR, Barsic-Tress N, Taylor L, Curthoys NP. The 3'-nontranslated

region of rat renal glutaminase mRNA contains a pH-responsive stability element.

Am J Physiol. 1996 Jul;271(1 Pt 2):F126-31. PubMed PMID: 8760253.

888: Nishizawa M, Matsue T, Uchida I. Penicillin sensor based on a microarray

electrode coated with pH-responsive polypyrrole. Anal Chem. 1992 Nov

1;64(21):2642-4. PubMed PMID: 1443627.

889: Bates RG, Covington AK. Behavior of the glass electrode and other

pH-responsive electrodes in biological media. Ann N Y Acad Sci. 1968 Feb

1;148(1):67-80. PubMed PMID: 5237649.